Use of Figures in Literature Mining for Biomedical Digital Libraries

2006 ◽  
Author(s):  
Nawei Chen ◽  
H. Shatka ◽  
D. Blostein
Keyword(s):  
Digital Libraries ◽  
Literature Mining

The prospects for IRBIS development: The new product - IRBIS64+

2017 ◽  
pp. 65-74 ◽  
Author(s):  
Alexander Brodovsky ◽  
Konstantin Sboichakov ◽  
Vladimir Sokolovsky
Keyword(s):  
Digital Libraries ◽  
New Product ◽  
Automation System ◽  
Library Automation ◽  
Expanded Access ◽  
Access Right

IRBIS64+ - the new product of IRBIS Library Automation System designed for building and maintaining digital libraries, is introduced. IRBIS64+ new functionality is revealed. New possibilities for users, including those with expanded access right, are described. The IRBIS64+ modules are named.

Digital Libraries

2011 ◽  
Vol 3 (2) ◽  
pp. 161-162
Author(s):  
Amitkumar Lalitbhai Ghoricha ◽  
Keyword(s):  
Digital Libraries

Factors Influencing the Adoption of Electronic Information Resources among Postgraduate Students in Nigerian Universities

Mousaion ◽  
2020 ◽  
Vol 38 (2) ◽  
Author(s):  
Kehinde Abayomi Owolabi ◽  
Basirat.Olubukola Diyaolu ◽  
Nurudeen Adeniyi Aderibigbe ◽  
Mudasiru A Yusuf
Keyword(s):  
Information And Communication Technologies ◽  
Digital Libraries ◽  
Structural Equation ◽  
Information Resources ◽  
Behavioural Intention ◽  
Electronic Information ◽  
Cross Sectional ◽  
Postgraduate Students ◽  
Factors Influencing ◽  
Electronic Information Resources

The advent of information and communication technologies (ICTs) has revolutionised how library resources are made and transmitted to end-users. It has effectively improved the standard of education and research in tertiary institutions worldwide by providing various essential resources, including e-books, journals and databases. However, it has been observed that students still abstain from making the best usage of the digital library, instead using search engines rather than institutional digital libraries. This study investigated the factors influencing the behavioural intention of postgraduate (PG) students to use electronic information resources (EIRs). The Unified Theory of Acceptance of Technology (UTAUT) model was adopted. A cross-sectional research design was used to assess the factors influencing the use of EIRs. A sample of 362 PG students was determined using a Monte Carlo simulation approach. Data were collected from participants via the administration of 400 copies of the questionnaire. Confirmatory Factor Analysis (CFA) and the Covariance-Based Structural Equation Modelling (CB-SEM) were used to analyse data collected. The findings revealed that performance expectancy (PE) and effort expectancy (EE) were the two constructs that influenced PG students’ behavioural intention to use EIRs. In contrast, social influence (SI) and facilitating condition (FC) did not change the PG students’ behavioural plan to use EIRs. The study recommended the need for adequate training for postgraduate (PG) students on the obligation to accept and use EIRs.

Historia leksemu "badylarz" (na marginesie prac nad "Wielkim słownikiem języka polskiego PAN")

Język Polski ◽  
2020 ◽  
Vol 100 (3) ◽  
pp. 100-112
Author(s):  
Jakub Bobrowski
Keyword(s):  
Popular Culture ◽  
19Th Century ◽  
Interwar Period ◽  
Digital Libraries ◽  
Cultural Memory ◽  
Left Wing ◽  
Lexical Unit ◽  
Use Of Data ◽  
Polish Language ◽  
The 19Th Century

The article explores the semantic and pragmatic evolution of the lexical unit "badylarz" (‘vegetable gardener’). The author challenges the generally accepted opinions about its history, making use of data from dictionaries, digital libraries and corpora of the Polish language. It is commonly believed that the word came into existence during the PRL era and belonged to the typical elements of the discourse of communist propaganda. An analysis of the collected data showed that the word "badylarz" existed as far back as the second half of the 19th century. Originally, it was a neutral lexeme, but in the interwar period it became one of the offensive names of class enemies, often used in left-wing newspapers. After the war, negative connotations of the word were disseminated through literature and popular culture. Nowadays, "badylarz" functions as the lexical exponent of cultural memory of communist times.

Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China

2020 ◽  
Vol 21 ◽  
Author(s):  
Xuan Yu ◽  
Zixuan Chu ◽  
Jian Li ◽  
Rongrong He ◽  
Yaya Wang ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Drug Interactions ◽  
Penicillin G ◽  
Literature Mining ◽  
Human Pharmacokinetics ◽  
P450 Enzyme ◽  
Drug Drug Interaction ◽  
Pharmacokinetic Drug ◽  
Sepsis Care

Background: Many antibiotics have a high potential for having an interaction with drugs, as perpetrator and/or victim, in critically ill patients, and particularly in sepsis patients. Methods: The aim of this review is to summarize the pharmacokinetic drug-drug interaction (DDI) of 45 antibiotics commonly used in sepsis care in China. Literature mining was conducted to obtain human pharmacokinetics/dispositions of the antibiotics, their interactions with drug metabolizing enzymes or transporters, and their associated clinical drug interactions. Potential DDI is indicated by a DDI index > 0.1 for inhibition or a treated-cell/untreated-cell ratio of enzyme activity being > 2 for induction. Results: The literature-mined information on human pharmacokinetics of the identified antibiotics and their potential drug interactions is summarized. Conclusion: Antibiotic-perpetrated drug interactions, involving P450 enzyme inhibition, have been reported for four lipophilic antibacterials (ciprofloxacin, erythromycin, trimethoprim, and trimethoprim-sulfamethoxazole) and three lipophilic antifungals (fluconazole, itraconazole, and voriconazole). In addition, seven hydrophilic antibacterials (ceftriaxone, cefamandole, piperacillin, penicillin G, amikacin, metronidazole, and linezolid) inhibit drug transporters in vitro. Despite no reported clinical PK drug interactions with the transporters, caution is advised in the use of these antibacterials. Eight hydrophilic antibacterials (all β-lactams; meropenem, cefotaxime, cefazolin, piperacillin, ticarcillin, penicillin G, ampicillin, and flucloxacillin), are potential victims of drug interactions due to transporter inhibition. Rifampin is reported to perpetrate drug interactions by inducing CYP3A or inhibiting OATP1B; it is also reported to be a victim of drug interactions, due to the dual inhibition of CYP3A4 and OATP1B by indinavir. In addition, three antifungals (caspofungin, itraconazole, and voriconazole) are reported to be victims of drug interactions because of P450 enzyme induction. Reports for other antibiotics acting as victims in drug interactions are scarce.

Preliminary Study on the Mechanism of Carvacrol Regulating Hepatocellular Carcinoma Based on Network Pharmacology

2019 ◽  
Vol 16 (11) ◽  
pp. 1286-1295
Author(s):  
Sha Li ◽  
Haixia Zhao ◽  
Lidao Bao
Keyword(s):  
Hepatocellular Carcinoma ◽  
Western Blot ◽  
Target Prediction ◽  
Network Pharmacology ◽  
Literature Mining ◽  
Active Compounds ◽  
Prediction Server ◽  
Preliminary Study ◽  
Alignment Analysis ◽  
Endogenous Interactions

Objective: To predict and analyze the target of anti-Hepatocellular Carcinoma (HCC) in the active constituents of Safflower by using network pharmacology. Methods: The active compounds of safflower were collected by TCMSP, TCM-PTD database and literature mining methods. The targets of active compounds were predicted by Swiss Target Prediction server, and the target of anti-HCC drugs was collected by DisGeNET database. The target was subjected to an alignment analysis to screen out Carvacrol, a target of safflower against HCC. The mouse HCC model was established and treated with Carvacrol. The anti-HCC target DAPK1 and PPP2R2A were verified by Western blot and co-immunoprecipitation. Results: A total of 21 safflower active ingredients were predicted. Carvacrol was identified as a possible active ingredient according to the five principles of drug-like medicine. According to Carvacrol's possible targets and possible targets of HCC, three co-targets were identified, including cancer- related are DAPK1 and PPP2R2A. After 20 weeks of Carvacrol treated, Carvacrol group significantly increased on DAPK1 levels and decreased PPP2R2A levels in the model mice by Western blot. Immunoprecipitation confirmed the endogenous interaction between DAPK1 and PPP2R2A. Conclusion: Safflower can regulate the development of HCC through its active component Carvacrol, which can affect the expression of DAPK1 and PPP2R2A proteins, and the endogenous interactions of DAPK1 and PPP2R2A proteins.

UNDER-GRADUATE STUDENTS AND THE ROLE OF E- LIBRARIES TO UPLIFT THE QUALITY OF HIGHER EDUCATION

2018 ◽  
Vol 6 (26) ◽  
Author(s):  
Dharambeer Singh
Keyword(s):  
Graduate Students ◽  
Digital Libraries ◽  
Rural Areas ◽  
Multiple Access ◽  
Information Needs ◽  
Quality Of Higher Education ◽  
Brick And Mortar ◽  
Education Status

Digital libraries, designed to serve people and their information needs in the same way as traditional libraries, present distinct advantages over brick and mortar facilities: elimination of physical boundaries, round-the-clock access to information, multiple access points, networking abilities, and extended search functions. As a result, they should be especially well-suited for the disables. However, minorities, those affected by lower income and education status, persons living in rural areas, the physically challanged, and developing countries as a whole consistently suffer from a lack of accessibility to digital libraries. This paper evaluates the effectiveness and relevance of digital libraries currently in place and discusses what could and should be done to improve accessibility to digital libraries for under-graduate students.

Sign in / Sign up

Export Citation Format

Share Document