Enable Communications Between The RSW Control Criteria and SIP Using R2SP

2006 ◽  
Author(s):  
O. Abouabdalla ◽  
R. Sureswaran
Keyword(s):  
Control Criteria

Advances in standardizing and validating research techniques for pathogen monitoring in water

2004 ◽  
Vol 4 (2) ◽  
pp. 23-30
Author(s):  
K. Connell ◽  
M. Pope ◽  
K. Miller ◽  
J. Scheller ◽  
J. Pulz
Keyword(s):  
Validation Studies ◽  
Development Process ◽  
Monitoring Methods ◽  
Microbiological Method ◽  
Validation Process ◽  
Method Performance ◽  
Target Analytes ◽  
Interlaboratory Validation ◽  
Quality Control Criteria ◽  
Control Criteria

Designing and conducting standardized microbiological method interlaboratory validation studies is challenging because most methods are manual, rather than instrument-based, and results from the methods are typically subjective. Determinations of method recovery, in particular, are problematic, due to difficulties in assessing the true spike amount. The standardization and validation process used for the seven most recent USEPA 1600-series pathogen monitoring methods has begun to address these challenges. A staged development process was used to ensure that methods were adequately tested and standardized before resources were dedicated to interlaboratory validation. The interlaboratory validation studies for USEPA Method 1622, for Cryptosporidium, USEPA Method 1601 for coliphage, and USEPA Method 1605 for Aeromonas assessed method performance using different approaches, due the differences in the nature of the target analytes and the data quality needs of each study. However, the use of enumerated spikes in all of the studies allowed method recovery and precision to be assessed, and also provided the data needed to establish quantitative quality control criteria for the methods.

Radar-aided CSO-control-criteria for an ecological approach

1997 ◽  
Vol 36 (8-9) ◽  
pp. 223-228
Author(s):  
A. Petruck ◽  
F. Sperling
Keyword(s):  
Critical Time ◽  
Integrated Approach ◽  
Control Measures ◽  
Real Time Control ◽  
Sewer System ◽  
Time Control ◽  
Physical Measurements ◽  
Combined Sewer ◽  
Receiving Stream ◽  
Control Criteria

The control strategy of a combined sewer system incorporating three stormwater storage tanks with overflows presented here attempts to consider all aspects of acute CSO effects. These are the hydraulic and the composition components as well as the time factor. The result is an integrated approach, which is not based on the classic emission view (i.e. reduction of volume), but on pollution criteria (i.e. possible harm to the biotic community). The aim is to reduce the exceeding of critical peak values of the CSO components at critical time intervals. Control decisions will be based on continuous measurements in the sewer system and in the receiving stream. Furthermore the measurements are carried out to determine the effects (both hydraulic and chemical) of particular CSO discharges in order to evolve the critical values for the project area. The chemical and physical measurements are accompanied by a biological monitoring programme. Macroinvertebrates are sampled upstream and downstream of outfalls and at a reference site. This allows the evaluation of the control measures on an ecological basis, and thus an assessment of the ecological potential of radar-aided real-time control of the combined sewer systems.

Failure of Centers for Disease Control Criteria to Identify Hepatitis B Infection in a Large Municipal Obstetrical Population

1988 ◽  
Vol 43 (6) ◽  
pp. 340-341
Author(s):  
MAUREEN M. JONES ◽  
EUGENE R. SCHIFF ◽  
MARY J. OʼSULLIVAN ◽  
MARIA DE MEDINA ◽  
RAJENDER K. REDDY ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Disease Control ◽  
Hepatitis B Infection ◽  
Centers For Disease Control ◽  
Control Criteria

scholarly journals Assessment of SARS-CoV-2 genome sequencing: quality criteria and low frequency variants

2021 ◽  
Author(s):  
Damien Jacot ◽  
Trestan Pillonel ◽  
Gilbert Greub ◽  
Claire Bertelli
Keyword(s):  
Sample Selection ◽  
Low Frequency ◽  
Pcr Amplification ◽  
Quality Criterion ◽  
Quality Criteria ◽  
Sequencing Errors ◽  
Sequencing Quality ◽  
Quality Control Criteria ◽  
Control Criteria ◽  
Sequence Quality

Although many laboratories worldwide have developed their sequencing capacities in response to the need for SARS-CoV-2 genome-based surveillance of variants, only few reported some quality criteria to ensure sequence quality before lineage assignment and submission to public databases. Hence, we aimed here to provide simple quality control criteria for SARS-CoV-2 sequencing to prevent erroneous interpretation of low quality or contaminated data. We retrospectively investigated 647 SARS-CoV-2 genomes obtained over ten tiled amplicons sequencing runs. We extracted 26 potentially relevant metrics covering the entire workflow from sample selection to bioinformatics analysis. Based on data distribution, critical values were established for eleven selected metrics to prompt further quality investigations for problematic samples, in particular those with a low viral RNA quantity. Low frequency variants (<70% of supporting reads) can result from PCR amplification errors, sample cross contaminations or presence of distinct SARS-CoV2 genomes in the sample sequenced. The number and the prevalence of low frequency variants can be used as a robust quality criterion to identify possible sequencing errors or contaminations. Overall, we propose eleven metrics with fixed cutoff values as a simple tool to evaluate the quality of SARS-CoV-2 genomes, among which cycle thresholds, mean depth, proportion of genome covered at least 10x and the number of low frequency variants combined with mutation prevalence data.

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