Unveiling Fuzzy Associations Between Breast Cancer Prognostic Factors and Gene Expression Data

Author(s):  
Francisco Javier López Domingo ◽  
Marta Cuadros Celorrio ◽  
Armando Blanco Moron ◽  
Ángel Concha Lopez
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Gaia Griguolo ◽  
Maria Vittoria Dieci ◽  
Laia Paré ◽  
Federica Miglietta ◽  
Daniele Giulio Generali ◽  
...  

AbstractLittle is known regarding the interaction between immune microenvironment and tumor biology in hormone receptor (HR)+/HER2− breast cancer (BC). We here assess pretreatment gene-expression data from 66 HR+/HER2− early BCs from the LETLOB trial and show that non-luminal tumors (HER2-enriched, Basal-like) present higher tumor-infiltrating lymphocyte levels than luminal tumors. Moreover, significant differences in immune infiltrate composition, assessed by CIBERSORT, were observed: non-luminal tumors showed a more proinflammatory antitumor immune infiltrate composition than luminal ones.


Methods ◽  
2020 ◽  
Vol 179 ◽  
pp. 89-100 ◽  
Author(s):  
Kyuri Jo ◽  
Beatriz Santos-Buitrago ◽  
Minsu Kim ◽  
Sungmin Rhee ◽  
Carolyn Talcott ◽  
...  

2013 ◽  
Vol 8 (1) ◽  
Author(s):  
Anirban Bhar ◽  
Martin Haubrock ◽  
Anirban Mukhopadhyay ◽  
Ujjwal Maulik ◽  
Sanghamitra Bandyopadhyay ◽  
...  

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