Comparative Study of a DNA Sequence Storage Technique: An Improved Coding Method for Information Storage of DNA from Characters to Numbers

2016 ◽  
Author(s):  
Crystal Cob ◽  
Soo-Yeon Ji
Keyword(s):  
Comparative Study ◽  
Dna Sequence ◽  
Information Storage ◽  
Coding Method ◽  
Sequence Storage ◽  
Storage Technique

scholarly journals Modular non-repeating codes for DNA storage

2016 ◽  
Author(s):  
Ian Holmes
Keyword(s):  
Dna Sequence ◽  
Block Code ◽  
Information Storage ◽  
State Machines ◽  
Sequencing Technologies ◽  
Finite State Transducers ◽  
Dna Storage ◽  
Finite State ◽  
Simulation Results ◽  
Weighted Finite State Transducers

1AbstractWe describe a strategy for constructing codes for DNA-based information storage by serial composition of weighted finite-state transducers. The resulting state machines can integrate correction of substitution errors; synchronization by interleaving watermark and periodic marker signals; conversion from binary to ternary, quaternary or mixed-radix sequences via an efficient block code; encoding into a DNA sequence that avoids homopolymer, dinucleotide, or trinucleotide runs and other short local repeats; and detection/correction of errors (including local duplications, burst deletions, and substitutions) that are characteristic of DNA sequencing technologies. We present software implementing these codes, available at https://github.com/ihh/dnastore, with simulation results demonstrating that the generated DNA is free of short repeats and can be accurately decoded even in the presence of substitutions, short duplications and deletions.

scholarly journals Addition of Degenerate Bases to DNA-based Data Storage for Increased Information Capacity

2018 ◽  
Author(s):  
Yeongjae Choi ◽  
Taehoon Ryu ◽  
Amos C. Lee ◽  
Hansol Choi ◽  
Hansaem Lee ◽  
...  
Keyword(s):  
Dna Sequence ◽  
Data Storage ◽  
Information Storage ◽  
Promising Method ◽  
Information Capacity ◽  
Practical Implementation ◽  
Increasing Demand ◽  
The Cost

Introductory paragraphDNA-based data storage has emerged as a promising method to satisfy the exponentially increasing demand for information storage. However, practical implementation of DNA-based data storage remains a challenge because of the high cost of DNA per unit data. Here, we propose the use of eleven degenerate bases as encoding characters in addition to A, C, G, and T, which increases the information capacity (the amount of data that can be stored per length of DNA sequence designed) and reduce the cost of DNA per unit data. Using the proposed method, we experimentally achieved an information capacity of 3.37 bits/character, which is more than twice when compared to the highest information capacity previously achieved. Finally, the platform was projected to reduce the cost of DNA-based data storage by 50%.

DNA sequence compression using RP/GP2 method with information storage and security

2019 ◽  
Vol 26 (7) ◽  
pp. 2159-2172
Author(s):  
Syed Mahamud Hossein ◽  
Debashis De ◽  
Pradeep Kumar Das Mohapatra
Keyword(s):  
Dna Sequence ◽  
Information Storage ◽  
Dna Sequence Compression ◽  
Sequence Compression
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