A Domain Specific Modeling Framework for Secure Network Applications

2006 ◽  
Author(s):  
Hiroshi Wada ◽  
Junichi Suzuki
Keyword(s):  
Modeling Framework ◽  
Network Applications ◽  
Domain Specific ◽  
Domain Specific Modeling ◽  
Secure Network ◽  
Specific Modeling

scholarly journals Accelerated Predictive Healthcare Analytics with Pumas, a High Performance Pharmaceutical Modeling and Simulation Platform

2020 ◽  
Author(s):  
Chris Rackauckas ◽  
Yingbo Ma ◽  
Andreas Noack ◽  
Vaibhav Dixit ◽  
Patrick Kofod Mogensen ◽  
...  
Keyword(s):  
Parameter Estimation ◽  
Automatic Differentiation ◽  
Quantitative Relationship ◽  
Estimation Methods ◽  
Stiff Systems ◽  
Modeling Framework ◽  
Domain Specific ◽  
Wide Range ◽  
Domain Specific Modeling ◽  
Specific Modeling

AbstractPharmacometric modeling establishes causal quantitative relationship between administered dose, tissue exposures, desired and undesired effects and patient’s risk factors. These models are employed to de-risk drug development and guide precision medicine decisions. Recent technological advances rendered collecting real-time and detailed data easy. However, the pharmacometric tools have not been designed to handle heterogeneous, big data and complex models. The estimation methods are outdated to solve modern healthcare challenges. We set out to design a platform that facilitates domain specific modeling and its integration with modern analytics to foster innovation and readiness to data deluge in healthcare.New specialized estimation methodologies have been developed that allow dramatic performance advances in areas that have not seen major improvements in decades. New ODE solver algorithms, such as coefficient-optimized higher order integrators and new automatic stiffness detecting algorithms which are robust to frequent discontinuities, give rise to up to 4x performance improvements across a wide range of stiff and non-stiff systems seen in pharmacometric applications. These methods combine with JIT compiler techniques and further specialize the solution process on the individual systems, allowing statically-sized optimizations and discrete sensitivity analysis via forward-mode automatic differentiation, to further enhance the accuracy and performance of the solving and parameter estimation process. We demonstrate that when all of these techniques are combined with a validated clinical trial dosing mechanism and non-compartmental analysis (NCA) suite, real applications like NLME parameter estimation see run times halved while retaining the same accuracy. Meanwhile in areas with less prior optimization of software, like optimal experimental design, we see orders of magnitude performance enhancements. Together we show a fast and modern domain specific modeling framework which lays a platform for innovation via upcoming integrations with modern analytics.

scholarly journals Modeling for Rapid Systems Prototyping: Hospital Situational Awareness System Design

Systems ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 12
Author(s):  
Avi Shaked
Keyword(s):  
Situational Awareness ◽  
Functional System ◽  
Modeling Framework ◽  
Modeling Tools ◽  
Domain Specific ◽  
Model Based ◽  
Domain Specific Modeling ◽  
System Prototype ◽  
Specific Modeling ◽  
Awareness System

The COVID-19 pandemic caught hospitals unprepared. The need to treat patients remotely and with limited resources led hospitals to identify a gap in their operational situational awareness. During the pandemic, Israeli Aerospace Industries helped hospitals to address the gap by designing a system to support their effective operation, management and decision making. In this paper, we report on the development of a functional, working prototype of the system using model-based engineering approach and tools. Our approach relies on domain-specific modeling, incorporating metamodeling and domain-specific representations based on the problem domain’s ontology. The tools practiced are those embedded into the Eclipse Modeling Framework—specifically, Ecore Tools and Sirius. While these technological tools are typically used to create dedicated, engineering-related modeling tools, in this work, we use them to create a functional system prototype. We discuss the advantages of our approach as well as the challenges with respect to the existing tools and their underlying technology. Based on the reported experience, we encourage practitioners to adopt model-based engineering as an effective way to develop systems. Furthermore, we call researchers and tool developers to improve the state-of-the-art as well as the existing implementations of pertinent tools to support model-based rapid prototyping.

scholarly journals Towards a Domain-Specific Modeling Language for Extracting Event Logs from ERP Systems

2021 ◽  
Vol 11 (12) ◽  
pp. 5476
Author(s):  
Ana Pajić Simović ◽  
Slađan Babarogić ◽  
Ognjen Pantelić ◽  
Stefan Krstović
Keyword(s):  
Process Mining ◽  
Modeling Language ◽  
Sufficient Information ◽  
Event Data ◽  
Erp Systems ◽  
Domain Experts ◽  
Domain Specific ◽  
Event Logs ◽  
Domain Specific Modeling ◽  
Specific Modeling

Enterprise resource planning (ERP) systems are often seen as viable sources of data for process mining analysis. To perform most of the existing process mining techniques, it is necessary to obtain a valid event log that is fully compliant with the eXtensible Event Stream (XES) standard. In ERP systems, such event logs are not available as the concept of business activity is missing. Extracting event data from an ERP database is not a trivial task and requires in-depth knowledge of the business processes and underlying data structure. Therefore, domain experts require proper techniques and tools for extracting event data from ERP databases. In this paper, we present the full specification of a domain-specific modeling language for facilitating the extraction of appropriate event data from transactional databases by domain experts. The modeling language has been developed to support complex ambiguous cases when using ERP systems. We demonstrate its applicability using a case study with real data and show that the language includes constructs that enable a domain expert to easily model data of interest in the log extraction step. The language provides sufficient information to extract and transform data from transactional ERP databases to the XES format.

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