Suppressing arrhythmias in cardiac models with overdrive pacing

2002 ◽  
Author(s):  
G.V. Osipov ◽  
A.T. Stamp ◽  
J.J. Collins
Keyword(s):  
Overdrive Pacing ◽  
Cardiac Models

Loperamide Induced Recurrent Torsades de Pointes: A Case Report

2021 ◽  
pp. 089719002110048
Author(s):  
Gregory G. Jackson ◽  
Christine R. Lopez ◽  
Elizabeth S. Bermudez ◽  
Nina E. Hill ◽  
Dan M. Roden ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Torsades De Pointes ◽  
Altered Mental Status ◽  
Spontaneous Circulation ◽  
Prior History ◽  
Common Phenomenon ◽  
Medical Providers ◽  
Return Of Spontaneous Circulation ◽  
History Of ◽  
Overdrive Pacing

Purpose: A case of loperamide-induced recurrent torsades de pointes is reported to raise awareness of an increasingly common phenomenon that could be encountered by medical providers during the current opioid epidemic. Summary: A 40 year-old-man with a prior history of opioid abuse who presented to the emergency department after taking up to 100 tablets of loperamide 2 mg daily for 5 years to blunt opioid withdrawal symptoms and was subsequently admitted to the intensive care unit for altered mental status and hyperthermia. The patient had prolonged QTc and 2 episodes of torsades de pointes (TdP) that resulted in cardiac arrest with return of spontaneous circulation. He was managed with isoproterenol, overdrive pacing, and methylnatrexone with no other events of TdP or cardiac arrest. Conclusion: A 40-year-old male who developed torsades de pointes from loperamide overdose effectively treated with overdrive pacing, isoproterenol, and methylnatrexone.

scholarly journals Advanced Cardiac Models: Considerations for the Bioengineering of Advanced Cardiac In Vitro Models of Myocardial Infarction (Small 15/2021)

Small ◽  
2021 ◽  
Vol 17 (15) ◽  
pp. 2170067
Author(s):  
Poonam Sharma ◽  
Xiaowei Wang ◽  
Clara Liu Chung Ming ◽  
Laura Vettori ◽  
Gemma Figtree ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
In Vitro Models ◽  
Cardiac Models

Importance of parameter control in cardiac models for robust pro-arrhythmic risk prediction

2016 ◽  
Vol 81 ◽  
pp. 361
Author(s):  
Ken Wang ◽  
Mark Davies ◽  
Antonello Caruso ◽  
Gary Mirams ◽  
Denis Noble ◽  
...  
Keyword(s):  
Risk Prediction ◽  
Parameter Control ◽  
Cardiac Models
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