Classification of Relapse Ovarian Cancer on MALDI-TOF Mass Spectrometry Data

Author(s):  
Jung Hun Oh ◽  
Animesh Nandi ◽  
Prem Gurnani ◽  
Lynne Knowles ◽  
John Schorge ◽  
...  
2005 ◽  
Vol 4 (12) ◽  
pp. 1990-1999 ◽  
Author(s):  
Timothy W. Randolph ◽  
Bree L. Mitchell ◽  
Dale F. McLerran ◽  
Paul D. Lampe ◽  
Ziding Feng

Author(s):  
D. V. Ul’shina ◽  
D. A. Kovalev ◽  
I. V. Kuznetsova ◽  
O. V. Bobrysheva ◽  
T. L. Krasovskaya ◽  
...  

The effectiveness of differentiation of bacterial pathogens using MALDI-TOF mass spectrometry depends on the quality of sample preparation, compliance with mass spectrometric analysis parameters and statistical approaches used, implemented by various modern software tools. The review provides a brief description of the most known software used in the processing and bioinformation analysis of time-of-flight mass spectrometry data. A list of computer platforms, programs and environments, both commercial and publicly available, is presented. The results of indication and identification of pathogens of particularly dangerous and natural-focal infections by MALDI-TOF mass spectrometry using publicly available software – programming language R, Mass-Up, MicrobeMS, licensed – MatLab, ClinProTools, as well as free web applications, including, Speclust, Ribopeaksare provided. The data on usage of such well-known platforms as MALDI BioTyper, SARAMIS Vitek-MS and Andromas (Andromas SAS, France) for inter- and intra-specific differentiation of closely related species are presented. Results of identification and differentiation of microorganisms applying MALDI-TOF mass spectrometry based on detection of specific proteins for cross-comparison – biomarkers – are given. The analysis shows that the programming language R environment is one of the publicly available universal platforms with an optimal combination of algorithms for processing and interpreting of a large array of mass spectrometric data.


Author(s):  
HABTOM W. RESSOM ◽  
RENCY S VARGHESE ◽  
LENKA GOLDMAN ◽  
CHRISTOPHER A LOFFREDO ◽  
MOHAMED ABDEL-HAMID ◽  
...  

2003 ◽  
Vol 19 (13) ◽  
pp. 1636-1643 ◽  
Author(s):  
B. Wu ◽  
T. Abbott ◽  
D. Fishman ◽  
W. McMurray ◽  
G. Mor ◽  
...  

2008 ◽  
Vol 7 (2) ◽  
pp. 603-610 ◽  
Author(s):  
Habtom W. Ressom ◽  
Rency S. Varghese ◽  
Lenka Goldman ◽  
Yanming An ◽  
Christopher A. Loffredo ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0218951 ◽  
Author(s):  
Wenhao Tang ◽  
Nisha Ranganathan ◽  
Vahid Shahrezaei ◽  
Gerald Larrouy-Maumus

2012 ◽  
Vol 103 (2) ◽  
pp. 265-275 ◽  
Author(s):  
Hooi Jun Ng ◽  
Hayden K. Webb ◽  
Russell J. Crawford ◽  
François Malherbe ◽  
Henry Butt ◽  
...  

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