Region of Interest Detection in Fundus Images Using Deep Learning and Blood Vessel Information

Author(s):  
Jongwoo Kim ◽  
Sema Candemir ◽  
Emily Y. Chew ◽  
George R. Thoma
2021 ◽  
Author(s):  
◽  
Hiram José Sandoval-Cuellar

Glaucoma is an eye disease that gradually affects the optic nerve. Intravascular high pressure can be controlled to prevent total vision loss, but early glaucoma detection is crucial. The optic disc has been a notable landmark for finding abnormalities in the retina. The rapid development of computer vision techniques has made it possible to analyze eye conditions from images enabling to help a specialist to make a diagnosis using a technique that is non-invasive in its initial stage through fundus images. We propose a methodology glaucoma detection using deep learning. A convolutional neural network (CNN) is trained to extract multiple features, to classify fundus images. The accuracy, sensitivity, and the area under the curve obtained using the ORIGA database are 93.22%, 94.14%, and 93.98%. The use of the algorithm for the automatic region of interest detection in conjunction with our CNN structure considerably increases the glaucoma detecting accuracy in the ORIGA database.


2021 ◽  
Author(s):  
Abirami M.S ◽  
Vennila B ◽  
Suganthi K ◽  
Sarthak Kawatra ◽  
Anuja Vaishnava

Abstract In this study, we intend to diagnose Choroidal Neovascularization in retinal Optical Coherence Tomography (OCT) images using Deep Learning Architectures. Optical Coherence Tomography (OCT) images can be used to differentiate between a healthy eye and an eye with CNV disease. DenseNet and Vgg16 Architectures of Deep Learning were used in the study and the hyper parameters of both of the architectures were changed to diagnose the disease properly. After the detection of the disease, the diseased OCT images are segmented from the background for the Region of Interest detection using Python OpenCV library that is used for the processing of images. The results of implementation of the Architectures showed that Vgg16 showed better results in detecting the images rather than Dense Net Architecture with an accuracy percentage of 97.53% approximately a percent greater than Dense Net.


Author(s):  
Yuejun Liu ◽  
Yifei Xu ◽  
Xiangzheng Meng ◽  
Xuguang Wang ◽  
Tianxu Bai

Background: Medical imaging plays an important role in the diagnosis of thyroid diseases. In the field of machine learning, multiple dimensional deep learning algorithms are widely used in image classification and recognition, and have achieved great success. Objective: The method based on multiple dimensional deep learning is employed for the auxiliary diagnosis of thyroid diseases based on SPECT images. The performances of different deep learning models are evaluated and compared. Methods: Thyroid SPECT images are collected with three types, they are hyperthyroidism, normal and hypothyroidism. In the pre-processing, the region of interest of thyroid is segmented and the amount of data sample is expanded. Four CNN models, including CNN, Inception, VGG16 and RNN, are used to evaluate deep learning methods. Results: Deep learning based methods have good classification performance, the accuracy is 92.9%-96.2%, AUC is 97.8%-99.6%. VGG16 model has the best performance, the accuracy is 96.2% and AUC is 99.6%. Especially, the VGG16 model with a changing learning rate works best. Conclusion: The standard CNN, Inception, VGG16, and RNN four deep learning models are efficient for the classification of thyroid diseases with SPECT images. The accuracy of the assisted diagnostic method based on deep learning is higher than that of other methods reported in the literature.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marion R. Munk ◽  
Thomas Kurmann ◽  
Pablo Márquez-Neila ◽  
Martin S. Zinkernagel ◽  
Sebastian Wolf ◽  
...  

AbstractIn this paper we analyse the performance of machine learning methods in predicting patient information such as age or sex solely from retinal imaging modalities in a heterogeneous clinical population. Our dataset consists of N = 135,667 fundus images and N = 85,536 volumetric OCT scans. Deep learning models were trained to predict the patient’s age and sex from fundus images, OCT cross sections and OCT volumes. For sex prediction, a ROC AUC of 0.80 was achieved for fundus images, 0.84 for OCT cross sections and 0.90 for OCT volumes. Age prediction mean absolute errors of 6.328 years for fundus, 5.625 years for OCT cross sections and 4.541 for OCT volumes were observed. We assess the performance of OCT scans containing different biomarkers and note a peak performance of AUC = 0.88 for OCT cross sections and 0.95 for volumes when there is no pathology on scans. Performance drops in case of drusen, fibrovascular pigment epitheliuum detachment and geographic atrophy present. We conclude that deep learning based methods are capable of classifying the patient’s sex and age from color fundus photography and OCT for a broad spectrum of patients irrespective of underlying disease or image quality. Non-random sex prediction using fundus images seems only possible if the eye fovea and optic disc are visible.


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