CT scans with neurocysticercosis in epileptics patients: a computer-based method for detection and quantification

Author(s):  
E. Comunello ◽  
A. von Wangenheim ◽  
J.M. Barreto ◽  
P.S. Borges ◽  
P.R. Wille ◽  
...  
2013 ◽  
Vol 73 (3) ◽  
pp. 544-550 ◽  
Author(s):  
Sovira Tan ◽  
Jianhua Yao ◽  
John A Flynn ◽  
Lawrence Yao ◽  
Michael M Ward

ObjectiveSyndesmophyte growth in ankylosing spondylitis can be difficult to measure using radiographs because of poor visualisation and semiquantitative scoring methods. We developed and tested the reliability and validity of a new computer-based method that fully quantifies syndesmophyte volumes and heights on CT scans.MethodsIn this developmental study, we performed lumbar spine CT scans on 38 patients and used our algorithm to compute syndesmophyte volume and height in four intervertebral disk spaces. To assess reliability, we compared results between two scans performed on the same day in nine patients. To assess validity, we compared computed measures to visual ratings of syndesmophyte volume and height on both CT scans and radiographs by two physician readers.ResultsCoefficients of variation for syndesmophyte volume and height, based on repeat scans, were 2.05% and 2.40%, respectively. Based on Bland–Altman analysis, an increase in syndesmophyte volume of more than 4% or in height of more than 0.20 mm represented a change greater than measurement error. Computed volumes and heights were strongly associated with physician ratings of syndesmophyte volume and height on visual examination of both the CT scans (p<0.0001) and plain radiographs (p<0.002). Syndesmophyte volumes correlated with the Schober test (r=−0.48) and lateral thoracolumbar flexion (r=−0.60).ConclusionsThis new CT-based method that fully quantifies syndesmophytes in three-dimensional space had excellent reliability and face and construct validity. Given its high precision, this method shows promise for longitudinal clinical studies of syndesmophyte development and growth.


2014 ◽  
Author(s):  
C. Jacobs ◽  
S.H.T. T. Opdam ◽  
E. M. van Rikxoort ◽  
O. M. Mets ◽  
J. Rooyackers ◽  
...  

2015 ◽  
Vol 11 (2) ◽  
pp. 213-219 ◽  
Author(s):  
Ozkan Tehli ◽  
Ahmet Murat Dursun ◽  
Caglar Temiz ◽  
Ilker Solmaz ◽  
Cahit Kural ◽  
...  

AbstractBACKGROUNDThe procedure of reconstruction after the removal of cranial fibrous dysplasia (FD) must be precise to achieve good functional and aesthetic results. Intraoperative modeling of implants is difficult and may cause cosmetic disturbances.OBJECTIVETo present our experience with the treatment of cranial FD using preoperative computer-based surgical planning of tumor removal with reconstruction of the cranium with custom-made titanium implants.METHODSFour patients underwent surgical treatment for cranial FD over a 2-year period. All patients were male with a mean age of 25.25 years and had monostotic-type FD. Computed tomography (CT) with 0.5-mm slices was obtained preoperatively. Computer-based planning of the tumor removal was performed, and a template was created by the computer to determine the margins of tumor removal. After this procedure, the preoperative computer-based construction of the titanium implant was performed. The patients underwent surgical treatment, and the tumor was removed with the use of this template. Then, the titanium implant was inserted onto the bone defect and fixed with mini-screws. Patients were followed up by periodic CT scans.RESULTSThe histological diagnosis of all patients was FD. No intraoperative or postoperative complications have occurred. Postoperative CT scans showed complete tumor removal and confirmed appropriate cosmetic reconstruction. The mean follow-up period was 15.25 months.CONCLUSIONComputer-based surgical planning associated with the production of custom-made titanium implants is a highly promising method for the treatment of cranial FD. Better radiological and cosmetic outcomes could be obtained by this technique with interdisciplinary work with medical designers.


2012 ◽  
Vol 59 (6) ◽  
pp. 1620-1632 ◽  
Author(s):  
Ulas Bagci ◽  
Jianhua Yao ◽  
Albert Wu ◽  
Jesus Caban ◽  
Tara N. Palmore ◽  
...  

2013 ◽  
Vol 40 (11) ◽  
pp. 113701 ◽  
Author(s):  
Ziyue Xu ◽  
Ulas Bagci ◽  
Andre Kubler ◽  
Brian Luna ◽  
Sanjay Jain ◽  
...  

Author(s):  
M. Marko ◽  
A. Leith ◽  
D. Parsons

The use of serial sections and computer-based 3-D reconstruction techniques affords an opportunity not only to visualize the shape and distribution of the structures being studied, but also to determine their volumes and surface areas. Up until now, this has been done using serial ultrathin sections.The serial-section approach differs from the stereo logical methods of Weibel in that it is based on the Information from a set of single, complete cells (or organelles) rather than on a random 2-dimensional sampling of a population of cells. Because of this, it can more easily provide absolute values of volume and surface area, especially for highly-complex structures. It also allows study of individual variation among the cells, and study of structures which occur only infrequently.We have developed a system for 3-D reconstruction of objects from stereo-pair electron micrographs of thick specimens.


Author(s):  
Nestor J. Zaluzec

The Information SuperHighway, Email, The Internet, FTP, BBS, Modems, : all buzz words which are becoming more and more routine in our daily life. Confusing terminology? Hopefully it won't be in a few minutes, all you need is to have a handle on a few basic concepts and terms and you will be on-line with the rest of the "telecommunication experts". These terms all refer to some type or aspect of tools associated with a range of computer-based communication software and hardware. They are in fact far less complex than the instruments we use on a day to day basis as microscopist's and microanalyst's. The key is for each of us to know what each is and how to make use of the wealth of information which they can make available to us for the asking. Basically all of these items relate to mechanisms and protocols by which we as scientists can easily exchange information rapidly and efficiently to colleagues in the office down the hall, or half-way around the world using computers and various communications media. The purpose of this tutorial/paper is to outline and demonstrate the basic ideas of some of the major information systems available to all of us today. For the sake of simplicity we will break this presentation down into two distinct (but as we shall see later connected) areas: telecommunications over conventional phone lines, and telecommunications by computer networks. Live tutorial/demonstrations of both procedures will be presented in the Computer Workshop/Software Exchange during the course of the meeting.


1973 ◽  
Vol 37 (8) ◽  
pp. 27-31
Author(s):  
HA Brody ◽  
LF Lucaccini ◽  
M Kamp ◽  
R Rozen

Sign in / Sign up

Export Citation Format

Share Document