Evaluation of Bioimpedance Spectroscopy for the Monitoring of the Fluid Status in an Animal Model

Author(s):  
Soren Weyer ◽  
Lisa Rothlingshofer ◽  
Marian Walter ◽  
Steffen Leonhardt ◽  
Ralf Bensberg
2014 ◽  
Vol 27 (1) ◽  
pp. 54
Author(s):  
C. Nash ◽  
T. Kuchel ◽  
J. Edwards ◽  
L. Chester ◽  
H. Hodak ◽  
...  

2020 ◽  
Vol 48 (1) ◽  
pp. 73-73
Author(s):  
Rachel Maurice ◽  
Vinai Modem ◽  
Alvaro Coronado Munoz

2005 ◽  
Vol 25 (3_suppl) ◽  
pp. 46-48 ◽  
Author(s):  
Elizabeth Lindley ◽  
Yvette Devine ◽  
Lisa Hall ◽  
Mary Cullen ◽  
Suzanne Cuthbert ◽  
...  

♦ Objective This study was carried out to evaluate a procedure for converting bioimpedance spectroscopy (BIS) data to a clinically useful measure of fluid status that is easily interpreted by nursing staff and patients. ♦ Design The ratio of extracellular water (ECW) to total body water (TBW) in a cohort of peritoneal dialysis (PD) patients was compared with the distribution for normal control subjects. The result was expressed as the difference between the measured ECW/TBW ratio and the mean ratio for age- and sex-matched controls divided by the standard deviation for the controls (the “hydration score”). Where possible, interventions were made to reduce the target weight in patients with a hydration score greater than +2.0. ♦ Setting This clinical study was carried out in the nurseled outpatient PD unit at St. James's University Hospital. BIS measurements were carried out during routine clinic visits. The data for the control subjects were obtained in a range of settings in the UK and the Czech Republic. ♦ Patients 31 PD patients (21 M, 10 F; aged 19 – 78 years) who came to the PD unit for routine procedures during the study participated. ♦ Results The mean hydration score for PD patients was significantly higher than for the control subjects (+1.3 vs 0.0, p < 0.0001). 11 (35%) patients had a hydration score greater than +2.0, compared with only 2.5% of the controls; systolic blood pressure was greater than 130 mmHg in only two of these patients. After a 3-month follow-up, a weight reduction of 3.6 ± 2.3 kg had been achieved in 7 patients through modality change and implementation of prescription changes, with no adverse effects. ♦ Conclusions Although this was a small study, all the data collected indicated that the hydration score provides a reliable indication of fluid status in PD patients. BIS measurements are now carried out at 6-month intervals and are used to monitor the effect of interventions.


2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Xavier Torterüe ◽  
Laurène Dehoux ◽  
Marie-Alice Macher ◽  
Olivier Niel ◽  
Thérésa Kwon ◽  
...  

2019 ◽  
Vol 24 (4) ◽  
pp. 373-379
Author(s):  
Mototsugu Tanaka ◽  
Yoshitaka Ishibashi ◽  
Yoshifumi Hamasaki ◽  
Yuka Kamijo ◽  
Mayumi Idei ◽  
...  

2018 ◽  
Vol 33 (9) ◽  
pp. 1601-1607 ◽  
Author(s):  
Indranil Dasgupta ◽  
David Keane ◽  
Elizabeth Lindley ◽  
Ihab Shaheen ◽  
Kay Tyerman ◽  
...  

2012 ◽  
Vol 45 (1) ◽  
pp. 229-232 ◽  
Author(s):  
Simon Paul Parmentier ◽  
Holger Schirutschke ◽  
Bertram Schmitt ◽  
Jens Schewe ◽  
Kay Herbrig ◽  
...  

Author(s):  
D. J. McComb ◽  
J. Beri ◽  
F. Zak ◽  
K. Kovacs

Gonadotroph cell adenomas of the pituitary are infrequent in human patients and are not invariably associated with altered gonadal function. To date, no animal model of this tumor type exists. Herein, we describe spontaneous gonadotroph cell adenomas in old male and female Sprague-Dawley rats by histology, immunocytology and electron microscopy.The material consisted of the pituitaries of 27 male and 38 female Sprague Dawley rats, all 26 months of age or older, removed at routine autopsy. Sections of formal in-fixed, paraffin-embedded tissue were stained with hematoxylin-phloxine-saffron (HPS), the PAS method and the Gordon-Sweet technique for the demonstration of reticulin fibers. For immunostaining, sections were exposed to anti-rat β-LH, anti-ratβ-TSH, anti-rat PRL, anti-rat GH and anti-rat ACTH 1-39. For electron microscopy, tissue was fixed in 2.5% glutaraldehyde, postfixed in 1% OsO4 and embedded in epoxy-resin. Tissue fixed in 10% formalin, embedded in epoxy resin without osmification, was used for immunoelectron microscopy.


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