Glucose concentration varies logarithmically under both glycemic conditions in a computationally reconstructed human energy pool network (HEPNet)

Author(s):  
Abhishek Sengupta ◽  
Priyanka Narad
PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0127918 ◽  
Author(s):  
Abhishek Sengupta ◽  
Monendra Grover ◽  
Amlan Chakraborty ◽  
Sarika Saxena

1977 ◽  
Vol 22 (4) ◽  
pp. 305-306
Author(s):  
HYMAN MELTZER
Keyword(s):  

1966 ◽  
Vol 51 (2) ◽  
pp. 193-202
Author(s):  
J. A. Antonioli ◽  
A. Vannotti

ABSTRACT 1. The metabolism of suspensions of circulating leucocytes has been studied after intramuscular injection of a dose of 50 mg/kg of a corticosteroid (cortisone acetate). The suspensions were incubated under aerobic conditions in the presence of a glucose concentration of 5.6 mm. Glucose consumption, lactate production, and variations in intracellular glycogen concentration were measured. After the administration of the corticosteroid, the anabolic processes of granulocyte metabolism were reversibly stimulated. Glucose consumption and lactate production increased 12 hours after the injection, but tended to normalize after 24 hours. The glycogen content of the granulocytes was enhanced, and glycogen synthesis during the course of the incubation was greatly stimulated. The action of the administered corticosteroid is more prolonged in females than in males. The injection of the corticosteroid caused metabolic modifications which resemble in their modulations and in their chronological development those found in circulating granulocytes of guinea-pigs suffering from sterile peritonitis. These results suggest, therefore, that, in the case of acute inflammation, the glucocorticosteroids may play an important role in the regulation of the metabolism of the blood leucocytes.


Diabetes ◽  
1977 ◽  
Vol 26 (5) ◽  
pp. 445-452 ◽  
Author(s):  
R. A. DeFronzo ◽  
R. Andres ◽  
T. A. Bedsoe ◽  
G. Boden ◽  
G. A. Faloona ◽  
...  

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