Characterization of benign and malignant solid breast masses using vascular morphology in 3D power Doppler ultrasound images

Author(s):  
Hong-Ting Chen ◽  
Yi-Ping Lien ◽  
Po-Ting Liu ◽  
Yu-Len Huang ◽  
Dar-Ren Chen
2016 ◽  
Vol 85 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Ali Kupeli ◽  
Sibel Kul ◽  
Ilker Eyuboglu ◽  
Sukru Oguz ◽  
Sevdegul Mungan

Author(s):  
AYŞEGÜL CANSU ◽  
EMİN AYAN ◽  
SİBEL KUL ◽  
İLKER EYÜBOĞLU ◽  
ŞÜKRÜ OĞUZ ◽  
...  

Background/aim: To evaluate the diagnostic value of vascular indices obtained using 3D power Doppler ultrasound (3DPDUS) in differentiation of benign and malignant thyroid nodules. Materials and methods: Sixty-seven patients (56 female, 11 male, mean age 44.6) with 81 thyroid nodules exhibiting mixed (peripheral and central) vascularization patterns and with the largest diameter of between 10 mm and 30 mm were prospectively evaluated using 3DPDUS. Nodule volume, vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL) software, and these indices were then compared with regard to the cyto-histopathology-based diagnosis. The optimum cutoff values for the differentiation of benign and malignant nodules were identified, and diagnostic efficacy was calculated using receiver operating characteristic (ROC) analysis. Results: Fifty-six of the 81 nodules included in this study were diagnosed as benign and 25 as malignant. Vascular indices in malignant nodules were significantly higher than those in benign nodules (p<0.05). In benign nodules, mean VI was 11.61 ± 6.88, mean FI was 39.75 ± 3.93 and VFI was 4.82 ± 2.94, compared to 18.64 ± 12.81, 41.82 ± 4.43 and 8.17 ± 6.37, respectively, in malignant nodules. The area under the curves (AUCs) were calculated as 0.68, 0.61 and 0.67 for VI, FI and VFI, respectively. At optimal cut-off values of 10.2 for VI, 40.8 for FI and 5.5 for VFI, sensitivity and specificity were 72%/55.4%, 68%/57.1% and 68%/67.9%, respectively. Conclusion: 3DPDUS could be useful in the characterization of thyroid nodules. Key words: Thyroid nodules; three-dimensional power Doppler ultrasound; vascular indices; VOCAL


2020 ◽  
Vol 27 (2) ◽  
pp. 198-203
Author(s):  
Huizhu Wang ◽  
Bing Yan ◽  
Lifang Yue ◽  
Mingyu He ◽  
Yuehua Liu ◽  
...  

2002 ◽  
Vol 9 (2) ◽  
pp. S384-S385 ◽  
Author(s):  
C.R Krestan ◽  
C Riedl ◽  
M Memarsadeghi ◽  
M Rudas ◽  
G Pfarl ◽  
...  

2007 ◽  
Vol 30 (4) ◽  
pp. 615-615
Author(s):  
N. Vrachnis ◽  
A. Alamanou ◽  
Z. Iliodromiti ◽  
A. Pavlaki ◽  
D. Botsis ◽  
...  

2009 ◽  
Vol 29 (9) ◽  
pp. 1609-1618 ◽  
Author(s):  
Jose L Bartha ◽  
Eva M Moya ◽  
Blas Hervías-Vivancos

The objective of the present study was to evaluate fetal cerebral circulation by using three-dimensional (3D) power Doppler ultrasound in normal and growth-restricted fetuses. A total of 100 normal grown fetuses were compared with other 25 with growth restriction (FGR). Three-dimensional power Doppler ultrasound was used to assess fetal cerebral 3D vascular indices: vascularization index, flow index (FI), and vascularization flow index (VFI). Both FI and VFI correlated positively with gestational age. On average, all the 3D vascular indices were increased in fetuses with FGR. The proportion of fetuses detected as having hemodynamic redistribution was higher when using 3D power Doppler indices than by means of the middle cerebral artery pulsatility index (52% versus 20%, P = 0.002). In conclusion, two of the three indices increased during gestation. All the fetal cerebral 3D vascular indices are increased in fetuses with FGR. In these fetuses, there were more cases suggesting hemodynamic redistribution than expected by conventional Doppler studies.


2014 ◽  
Vol 43 (3) ◽  
pp. 171-178 ◽  
Author(s):  
Lotte L. Nieuwenhuis ◽  
Heleen E. Betjes ◽  
Wouter J.K. Hehenkamp ◽  
Martijn W. Heymans ◽  
Hans A.M. Brolmann ◽  
...  

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