Head mouse system based on gyro- and opto-sensors

2010 ◽  
Author(s):  
Soochan Kim ◽  
Minje Park ◽  
Sasiporn Anumas ◽  
Jaeha Yoo
Keyword(s):  
Mouse System

scholarly journals Suppressive Effect of Juzentaihoto on Vascularization Induced by B16 Melanoma CellsIn VitroandIn Vivo

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Shintaro Ishikawa ◽  
Takako Ishikawa ◽  
Kazuhito Asano ◽  
Hiroshi Fujiwara ◽  
Mayumi Okada ◽  
...  
Keyword(s):  
Herbal Medicines ◽  
Suppressive Effect ◽  
B16 Melanoma ◽  
Vascular Endothelial ◽  
Internal Fluid ◽  
Cell Metastasis ◽  
Experimental Mouse ◽  
Therapeutic Mechanisms ◽  
Endothelial Growth Factor ◽  
Mouse System

Juzentaihoto (JTT) is well known to be one of Japanese herbal medicines, and used for the supplemental therapy of cancer patients with remarkable success. The present study, therefore, was undertaken to examine the possible therapeutic mechanisms of JTT on cancer using B16 melanoma cell (B16 cell)/experimental mouse system. JTT was well mixed with rodent chow at 3.0% concentrations, and was administered orally ad libitum. Administration of JTT was started one week before tumor cell injection and continued throughout the experiment. Administration of JTT into mice significantly inhibited tumor metastasis in lungs after intravenous injection of2×105B16 cells in a volume of 50 μL. JTT also significantly suppressed enlargement of tumor size in hind footpad after the subcutaneous injection of2×105(50 μL) B16 cells. In the second part of experiments, the chamber that containing B16 cells was buried in the murine back. In JTT administrated group, vascular endothelial growth factor (VEGF) of chamber internal fluid significantly decreased, and vascularization of chamber circumference was also inhibited. These results strongly suggest that oral administration of JTT caused decrease in the generation of VEGF, which is responsible for vascularization, and results in inhibition of B16 cell metastasis.

Activity in the Gastrointestinal Tract after Administration of Bone-Seeking Radiopharmaceuticals

1996 ◽  
Vol 37 (3P2) ◽  
pp. 785-790
Author(s):  
M. Cronhjort ◽  
C. Jonsson ◽  
S.-O. Nilsson ◽  
B. Garmelius ◽  
H. Jacobsson
Keyword(s):  
Gastrointestinal Tract ◽  
Gastric Secretion ◽  
Bone Scintigraphy ◽  
Significant Fraction ◽  
General Distribution ◽  
Submandibular Glands ◽  
Stomach Mucosa ◽  
Experimental Mouse ◽  
Gamma Counter ◽  
Mouse System

Purpose: To test the possibility that (radio)activity of non-pertechnetate nature is excreted into the gastrointestinal tract at bone scintigraphy. Material and Methods: The distribution of a bone-seeking radiopharmaceutical (99mTc-HDP) was studied in an experimental mouse system by dissecting different organs and assessing their activity with a gamma-counter. Results: A comparison of the activity of the submandibular glands, which are assumed to accumulate only pertechnetate, and the gastrointestinal tract showed that a significant fraction of the activity excreted into the gastrointestinal tract did not consist of pertechnetate. Part of the excretion took place in the stomach. It was not connected to a specific bone-seeking agent or 99Mo/99mTc generator. Nor did it increase with time between make-up and injection. The excretion of the non-pertechnetate acitvity was reduced by cimetidine and omeprazole. These gastric-secretion blocking drugs did not reduce excretion of pertechnetate or significantly affect the general distribution of the radiopharmaceutical. Conclusion: There is a significant excretion of non-pertechnetate activity in the gastrointestinal tract. Part of this may be caused by excretion of the undegraded radiopharmaceutical by the stomach mucosa.

scholarly journals Effect of Poly I : C-induced Interferon on Herpes Virus Hominis Infection in Vitro and in Vivo

1972 ◽  
Vol 27 (3) ◽  
pp. 220-222 ◽  
Author(s):  
Klaus Munk ◽  
Thomas Frick
Keyword(s):  
Embryonic Cells ◽  
Subsequent Infection ◽  
In Vivo Experiments ◽  
Herpesvirus Hominis ◽  
Hominis Infection ◽  
Herpès Virus ◽  
Mouse System ◽  
Different Origin

In this study the effect of poly I : C-induced interferon on Herpesvirus hominis (HVH) infection in vitro and in vivo was investigated.The in vitro results revealed a significant effect of interferon on infections of HVH strains of different origin in mouse embryonic cells.The in vivo experiments performed in the HVH-mouse system indicate that the effective induction of interferon in an aminal increases its resistance to subsequent infection with HVH.

Mouse system quality control is necessary before the use of new material for in vitro fertilization and embryo transfer

1987 ◽  
Vol 4 (1) ◽  
pp. 56-58 ◽  
Author(s):  
Jean Parinaud ◽  
Jean-Michel Reme ◽  
Xavier Monrozies ◽  
Serge Favrin ◽  
Marie-France Sarramon ◽  
...  
Keyword(s):  
Quality Control ◽  
In Vitro Fertilization ◽  
Embryo Transfer ◽  
System Quality ◽  
Vitro Fertilization ◽  
New Material ◽  
Mouse System
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