Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation

2010 ◽  
Author(s):  
Ke Huang ◽  
Kaiguo Yan ◽  
Yan Yu
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Dose Enhancement ◽  
Geant4 Monte Carlo Simulation

An investigation of the effect of gold nanoparticles with different concentrations on increasing absorbed dose: an empirical and simulation study

2018 ◽  
Vol 18 (02) ◽  
pp. 191-197
Author(s):  
Masoumeh Hoseinnezhad ◽  
Mohammad Mahdavi ◽  
Seyyed R. M. Mahdavi ◽  
Mobarake Mahdavizade
Keyword(s):  
Monte Carlo Simulation ◽  
Gold Nanoparticles ◽  
Monte Carlo ◽  
Absorbed Dose ◽  
Simulation Method ◽  
Dose Enhancement ◽  
Depth Dose ◽  
Optical Ct ◽  
Ct System ◽  
Monte Carlo Simulation Model

AbstractPurposeThe purpose of this study was to determine the dose enhancement factor (DEF) of gold nanoparticles in a dosimeter gel and construct percentage depth dose curves, using the Optical CT system and the Monte Carlo simulation model, to determine the effect of increasing the dose caused by increasing the concentration of gold nanoparticles at depths in the gel.Materials and methodsThe Magic-f Gel was made based on the relevant protocol in the physics lab. To determine the amount of the increase in the absorbed dose, the gold nanoparticles were added to the gel and irradiated. An increase in the dose after adding nanoparticles to the gel vials was estimated both with the Optical CT system and by the Monte Carlo simulation method.ResultsDose enhancement curves for doses of 2, 4 and 6 Gy were prepared for gel vials without adding nanoparticles, and nanoparticle gels at concentrations 0·17, 3 and 6 mM. Also, the DEF was estimated. For the 0·17 mM molar gel, the DEF for 2, 4 and 6 Gy was 0·7, 0·743 and 0·801, respectively. For the 3 mM gel, it was 1·98, 2·5 and 2·2, and for the 6 mM gel, it was 37·4, 4·24 and 4·71, respectively.ConclusionThe enhancement of the dose after adding gold nanoparticles was confirmed both by experimental data and by simulation data.

Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit

2015 ◽  
Vol 31 (8) ◽  
pp. 861-874 ◽  
Author(s):  
M.A. Bernal ◽  
M.C. Bordage ◽  
J.M.C. Brown ◽  
M. Davídková ◽  
E. Delage ◽  
...  
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Liquid Water ◽  
Low Energy ◽  
Structure Modeling ◽  
Track Structure ◽  
Geant4 Monte Carlo Simulation
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