Octree Based Representation and Volume Rendering of Three-Dimensional Medical Data Sets

2008 ◽  
Author(s):  
Weiwei Song ◽  
Shungang Hua ◽  
Zongying Ou ◽  
Hu An ◽  
Kaifeng Song
Keyword(s):  
Volume Rendering ◽  
Three Dimensional ◽  
Medical Data ◽  
Data Sets

The Use of Data Explorer as a 3-D Reconstruction Tool for Microscopy Data Sets

1997 ◽  
Vol 3 (S2) ◽  
pp. 1131-1132
Author(s):  
Jansma P.L ◽  
M.A. Landis ◽  
L.C. Hansen ◽  
N.C. Merchant ◽  
N.J. Vickers ◽  
...  
Keyword(s):  
Volume Rendering ◽  
Laser Scanning ◽  
Three Dimensional ◽  
Building Blocks ◽  
General Purpose ◽  
Data Sets ◽  
Laser Scanning Confocal Microscope ◽  
Use Of Data ◽  
Using Data ◽  
Microscopy Data

We are using Data Explorer (DX), a general-purpose, interactive visualization program developed by IBM, to perform three-dimensional reconstructions of neural structures from microscopic or optical sections. We use the program on a Silicon Graphics workstation; it also can run on Sun, IBM RS/6000, and Hewlett Packard workstations. DX comprises modular building blocks that the user assembles into data-flow networks for specific uses. Many modules come with the program, but others, written by users (including ourselves), are continually being added and are available at the DX ftp site, http://www.tc.cornell.edu/DXhttp://www.nice.org.uk/page.aspx?o=43210.Initally, our efforts were aimed at developing methods for isosurface- and volume-rendering of structures visible in three-dimensional stacks of optical sections of insect brains gathered on our Bio-Rad MRC-600 laser scanning confocal microscope. We also wanted to be able to merge two 3-D data sets (collected on two different photomultiplier channels) and to display them at various angles of view.

Automated Three-dimensional Volume Rendering of Helical Computed Tomographic Angiography for Aneurysms: An Advanced Application of Neuronavigation Technology

2005 ◽  
Vol 57 (suppl_1) ◽  
pp. 69-77 ◽  
Author(s):  
Lucia Benvenuti ◽  
Salvatore Chibbaro ◽  
Stefano Carnesecchi ◽  
Flavio Pulerà ◽  
Rolando Gagliardi
Keyword(s):  
Digital Subtraction Angiography ◽  
Ct Angiography ◽  
Volume Rendering ◽  
Intracranial Aneurysms ◽  
Surgical Navigation ◽  
Three Dimensional ◽  
Helical Ct ◽  
Data Sets ◽  
Digital Subtraction ◽  
Computed Tomographic

Abstract OBJECTIVE: To introduce the possibility of volume-rendered helical computed tomographic (CT) angiographic data sets by use of Medtronic StealthStation Treon surgical navigation technology (Medtronic Surgical Navigation Technologies, Louisville, CO) and to evaluate the clinical usefulness of the method in planning and performing surgical treatment of intracranial aneurysms. METHODS: Between November 2002 and July 2003, we studied 15 patients with suspected intracranial aneurysms. All patients but two received conventional digital subtraction angiography, which failed to provide the requested information. Helical CT angiography was performed in all patients, and data sets were transferred to the StealthStation system across an electronic network to be automatically postprocessed by use of three-dimensional (3-D) volume rendering. The 3-D volume-rendered images were accurately analyzed to obtain more complete information about the aneurysm and to provide accurate treatment planning. In all patients, the 3-D volume-rendered model was displayed on the screen of the StealthStation system for the duration of the surgical procedure and compared with the intraoperative image. RESULTS: Data sets from CT angiography were automatically postprocessed by the StealthStation in seconds with excellent results, providing us, before and during surgery, with additional information not always available on traditional digital subtraction angiographic investigation. Because of the very short time necessary to complete this process (<5 min to obtain 3-D volume-rendered images), it was possible to perform emergency clipping of the aneurysms in two patients who had been admitted in very compromised neurological conditions. In 12 patients, integrated digital subtraction angiography and automated 3-D volume-rendered images allowed an accurate presurgical evaluation. Furthermore, in all patients on whom surgery was performed, aneurysms were found in the exact location and with the same anatomic features as depicted by the 3-D volume-rendered models. CONCLUSION: Reports in the literature indicate that information gathered by CT angiography with volume rendering shows a significant impact on aneurysm management. The StealthStation system upgraded with the adequate algorithm seems to provide a time- and cost-effective method of performing automated 3-D volume rendering of CT angiography and provides an interesting alternative to the available investigation modalities in case of emergency.

scholarly journals Three-Dimensional Stereoscopic Volume Rendering of Malignant Pleural Mesothelioma

2012 ◽  
Vol 97 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Nathan M Mollberg ◽  
Nigel M Parsad ◽  
Samuel G Armato ◽  
Janani Vigneswaran ◽  
Hedy L Kindler ◽  
...  
Keyword(s):  
Malignant Pleural Mesothelioma ◽  
Volume Rendering ◽  
Accurate Determination ◽  
Three Dimensional ◽  
Volumetric Analysis ◽  
Preoperative Imaging ◽  
Multidetector Row Computed Tomography ◽  
Pleural Mesothelioma ◽  
Data Sets ◽  
Ct Data

Abstract Our objective was to investigate the application of three-dimensional (3D) stereoscopic volume rendering with perceptual colorization on preoperative imaging for malignant pleural mesothelioma. At present, we have prospectively enrolled 6 patients being considered for resection of malignant pleural mesothelioma that have undergone a multidetector-row computed tomography (CT) scan of the chest. The CT data sets were volume rendered without preprocessing. The resultant 3D rendering was displayed stereoscopically and used to provide information regarding tumor extent, morphology, and anatomic involvement. To demonstrate this technique, this information was compared with the corresponding two-dimensional CT grayscale axial images from two of these patients. Three-dimensional stereoscopic reconstructions of the CT data sets provided detailed information regarding the local extent of tumor that could be used for preoperative surgical planning. Three-dimensional stereoscopic volume rendering for malignant pleural mesothelioma is a novel approach. Combined with our innovative perceptual colorization algorithm, stereoscopic volumetric analysis potentially allows for the accurate determination of the extent of pleural mesothelioma with results difficult to duplicate using grayscale, multiplanar CT images.

Clinical applications of three-dimensional rendering of medical data sets

1998 ◽  
Vol 86 (3) ◽  
pp. 555-568 ◽  
Author(s):  
R. Shahidi ◽  
R. Tombropoulos ◽  
R.P. Grzeszczuk
Keyword(s):  
Three Dimensional ◽  
Clinical Applications ◽  
Medical Data ◽  
Data Sets

Computer-aided methods for 3-D visualization of serial sections and thick biological specimens

1992 ◽  
Vol 50 (2) ◽  
pp. 1060-1061
Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Three Dimensional ◽  
Neuritic Plaque ◽  
Dimensional Structure ◽  
Data Sets ◽  
Molecular Physiology ◽  
Research Activities ◽  
Computer Aided ◽  
Dimensional Reconstruction

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.

Three Dimensional Volume Rendering Virtual Endoscopy of the Ossicles Using a Multi-Row Detector CT: Applications and Limitations

2005 ◽  
Vol 53 (2) ◽  
pp. 85
Author(s):  
Su Yeon Kim ◽  
Sun Seob Choi ◽  
Myung Jin Kang ◽  
Tae Beom Shin ◽  
Ki Nam Lee ◽  
...  
Keyword(s):  
Volume Rendering ◽  
Three Dimensional ◽  
Virtual Endoscopy

scholarly journals Elastic transformation of histological slices allows precise co-registration with microCT data sets for a refined virtual histology approach

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jonas Albers ◽  
Angelika Svetlove ◽  
Justus Alves ◽  
Alexander Kraupner ◽  
Francesca di Lillo ◽  
...  
Keyword(s):  
Three Dimensional ◽  
High Specificity ◽  
Histopathological Analysis ◽  
Specific Information ◽  
Data Sets ◽  
Virtual Histology ◽  
Novel Approach ◽  
Cell Tissue ◽  
Immuno Histochemistry ◽  
3D Information

AbstractAlthough X-ray based 3D virtual histology is an emerging tool for the analysis of biological tissue, it falls short in terms of specificity when compared to conventional histology. Thus, the aim was to establish a novel approach that combines 3D information provided by microCT with high specificity that only (immuno-)histochemistry can offer. For this purpose, we developed a software frontend, which utilises an elastic transformation technique to accurately co-register various histological and immunohistochemical stainings with free propagation phase contrast synchrotron radiation microCT. We demonstrate that the precision of the overlay of both imaging modalities is significantly improved by performing our elastic registration workflow, as evidenced by calculation of the displacement index. To illustrate the need for an elastic co-registration approach we examined specimens from a mouse model of breast cancer with injected metal-based nanoparticles. Using the elastic transformation pipeline, we were able to co-localise the nanoparticles to specifically stained cells or tissue structures into their three-dimensional anatomical context. Additionally, we performed a semi-automated tissue structure and cell classification. This workflow provides new insights on histopathological analysis by combining CT specific three-dimensional information with cell/tissue specific information provided by classical histology.

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