scholarly journals Zinc and silver migration during rechargeable silver-zinc cell cycling

2002 ◽  
Author(s):  
H.L. Lewis ◽  
S.P. Wharton
Keyword(s):  
Cell Cycling

TNFα blockade inhibits T cell cycling by NOTCH-1 signaling

2010 ◽  
Vol 48 (08) ◽  
Author(s):  
L Werner ◽  
D Paclik ◽  
U Berndt ◽  
B Wiedenmann ◽  
A Sturm
Keyword(s):  
T Cell ◽  
Notch 1 ◽  
Cell Cycling

Diosmetin, a Potential p53 Activator, Performs Anticancer Effect by Regulating Cell Cycling and Cell Proliferation in HepG2 Cells

2017 ◽  
Vol 24 (5) ◽  
pp. 413-418
Author(s):  
Bin Liu ◽  
Miaomiao Zhang ◽  
Shuna Liu ◽  
Jie Ying ◽  
Jingjing Zhang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Hepg2 Cells ◽  
Anticancer Effect ◽  
Cell Cycling

The Novel Vascular Disrupting Agent ANG501 Induces Cell Cycle Arrest and Enhances Endothelial Cell Sensitivity to Radiation

2009 ◽  
Vol 2 ◽  
pp. CGM.S2596 ◽  
Author(s):  
Shona T. Dougherty ◽  
Sean E. Walker ◽  
Peter D. Davis ◽  
Graeme J. Dougherty
Keyword(s):  
Cell Cycle ◽  
Endothelial Cells ◽  
Normal Cell ◽  
Cell Cycle Progression ◽  
Stress Proteins ◽  
Vascular Disrupting Agent ◽  
Heat Shock Stress ◽  
Cell Cycling ◽  
Vascular Disrupting

The efficacy of approaches in which vascular disrupting agents (VDA) are used in combination with conventional chemotherapy and/or radiation therapy in the treatment of cancer might be improved if there were a better understanding of the cellular and molecular changes induced in normal and malignant cells as a result of VD A exposure. Toward this goal, murine endothelial cells were treated in vitro with ANG501, a novel stilbene VDA developed in our laboratory, and alterations in gene expression determined by genome-wide microarray analysis and subsequently confirmed by Western blot analysis. Among the genes that were shown to be induced upon brief exposure to non-cytotoxic doses of ANG501 were several involved in the control of cell cycle progression and apoptosis, including p21Wafl and the heat shock/stress proteins hsp25, hsp70 and anti-B-crystallin. Reflecting such induction, functional studies confirmed that normal cell cycling is temporarily inhibited following treatment with ANG501 such that the majority of cells accumulate at the radiation-sensitive G2/M phase of the cell cycle at 6 hr. The effects were transient and by 24 hr normal cell cycling had largely resumed. Combination experiments confirmed that endothelial cells treated 6 hr previously with ANG501 were more readily killed by radiation. Importantly, significant effects were evident at clinically relevant radiation doses. Taken together these findings emphasize the need to consider the radiosensitizing activity of VD As when developing therapies in which these promising compounds are used in combination with radiation.

scholarly journals The role of protein synthesis in cell cycling and cancer

2009 ◽  
Vol 3 (5-6) ◽  
pp. 402-408 ◽  
Author(s):  
Shai White-Gilbertson ◽  
David T. Kurtz ◽  
Christina Voelkel-Johnson
Keyword(s):  
Protein Synthesis ◽  
Cell Cycling

Efficient lentiviral transduction of liver requires cell cycling in vivo

10.1038/71673 ◽  
2000 ◽  
Vol 24 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Frank Park ◽  
Kazuo Ohashi ◽  
Winnie Chiu ◽  
Luigi Naldini ◽  
Mark A. Kay
Keyword(s):  
Lentiviral Transduction ◽  
Cell Cycling

scholarly journals Cell cycling and patterned cell proliferation in the wing primordium of Drosophila.

1996 ◽  
Vol 93 (2) ◽  
pp. 640-645 ◽  
Author(s):  
M. Milan ◽  
S. Campuzano ◽  
A. Garcia-Bellido
Keyword(s):  
Cell Proliferation ◽  
Cell Cycling
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