Author(s):  
Alfredo I. Hernández ◽  
Virginie Le Rolle ◽  
Antoine Defontaine ◽  
Guy Carrault

The role of modelling and simulation in the systemic analysis of living systems is now clearly established. Emerging disciplines, such as systems biology, and worldwide research actions, such as the Physiome Project or the Virtual Physiological Human, are based on an intensive use of modelling and simulation methodologies and tools. One of the key aspects in this context is to perform an efficient integration of various models representing different biological or physiological functions, at different resolutions, spanning through different scales. This paper presents a multiformalism modelling and simulation environment (M2SL) that has been conceived to ease model integration. A given model is represented as a set of coupled and atomic model components that may be based on different mathematical formalisms with heterogeneous structural and dynamical properties. A co-simulation approach is used to solve these hybrid systems. The pioneering model of the overall regulation of the cardiovascular system proposed by Guyton and co-workers in 1972 has been implemented under M2SL and a pulsatile ventricular model based on a time-varying elastance has been integrated in a multi-resolution approach. Simulations reproducing physiological conditions and using different coupling methods show the benefits of the proposed environment.


2020 ◽  
Vol 2020 (14) ◽  
pp. 1026-1029
Author(s):  
Wang Xiaolu ◽  
Wang Danyang ◽  
Wu Hao ◽  
Yu Jian ◽  
Guo Peng ◽  
...  

2018 ◽  
Vol 225 ◽  
pp. 06021
Author(s):  
Mohd Zulhilmi P. Ismadi ◽  
Jundika C. Kurnia ◽  
Shaharin A. Sulaiman ◽  
Suhaimi Hassan ◽  
Mokhtar Awang ◽  
...  

With the continuous improvement in Computer Modelling and Simulation Environment (CMSE) applications being made, computer modelling and simulation (CMS) is proven a better alternative as opposed to conventional physical modelling. The advancement of computing hardware allows accurate results to be obtained faster, safer and at a fraction of its original cost. Despite the proven advantages, CMSE adoption among companies may be fairly new in Malaysia. This study is aimed at quantifying the demand of CMSE specialists in Malaysia as well as gaining insights in the companies’ requirements of specialists’ knowledge, competencies and skills. Thus, a survey, consisted of 3 main parts, was conducted among industries in Malaysia as a tool of measurement of the demand. The survey included questions related to the general information of the organization, specialists’ competencies relation to the job scope, and finally the professional and educational standards among specialists. In general, it was found that practically-competent specialists in CMSE are in high demand among engineering companies. Furthermore, professional courses through distance learning would be of high interest among companies to send their employees to gain practical competency in CMSE.


Author(s):  
Elias B. Sayah ◽  
Kishor P

This research presented a practically achievable scenario of a smart warehouse receiving smart containers to be inspected smartly and effectively. This research had four objectives: review role of augmented and virtual realities in construction warehousing; define a scenario in an example construction warehousing layout and create modelling and simulation environment in Blender; simulate the scenario in interactive mode and record the features and experiences; and make recommendations for its practical implementation. A 3D model of an example scenario of inspection of containers was created in Blender software, and its Augmented Reality (AR) functionalities were configured for a simulated experience. An example process of inspection of the containers offloaded in a temporary construction warehouse was experienced within the 3D model and key features and experiences were recorded.


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