Experimental Study Regarding the Comparative Behavior of Three Osteoconductive Bone Graft Substitutes

2010 ◽  
Author(s):  
P.D. Sirbu ◽  
R. Asaftei ◽  
M. Danciu ◽  
R. Mihaila ◽  
Luminita Simion ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Graft ◽  
Bone Graft Substitutes

An Experimental Study of Tricalcium Phosphate (TCP) as a Bone Graft Substitutes of Bone Defects in Canine Femur

1990 ◽  
Vol 25 (2) ◽  
pp. 545
Author(s):  
Ik Dong Kim ◽  
Poong Taek Kim ◽  
Byung Chul Park ◽  
Young Wook Choi ◽  
Young Goo Lyu ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Graft ◽  
Tricalcium Phosphate ◽  
Bone Defects ◽  
Bone Graft Substitutes

scholarly journals Dimensional Ridge Preservation with a Novel Highly Porous TiO2Scaffold: An Experimental Study in Minipigs

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Hanna Tiainen ◽  
Anders Verket ◽  
Håvard J. Haugen ◽  
S. Petter Lyngstadaas ◽  
Johan Caspar Wohlfahrt
Keyword(s):  
Experimental Study ◽  
Bone Graft ◽  
Tooth Extraction ◽  
Alveolar Bone ◽  
Ridge Preservation ◽  
Convex Shape ◽  
Prosthetic Reconstruction ◽  
Defect Site ◽  
Bone Graft Substitutes ◽  
Highly Porous

Despite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of novel TiO2scaffolds on dimensional ridge preservation was evaluated following their placement into surgically modified extraction sockets in the premolar region of minipig mandibles. After six weeks of healing, the scaffolds were wellintegrated in the alveolar bone, and the convex shape of the alveolar crest was preserved. The scaffolds were found to partially preserve the dimensions of the native buccal and lingual bone walls adjacent to the defect site. A tendency towards more pronounced vertical ridge resorption, particularly in the buccal bone wall of the nongrafted alveoli, indicates that the TiO2scaffold may be used for suppressing the loss of bone that normally follows tooth extraction.

scholarly journals Synthetic bone graft versus autograft or allograft for spinal fusion: a systematic review

2016 ◽  
Vol 25 (4) ◽  
pp. 509-516 ◽  
Author(s):  
Zorica Buser ◽  
Darrel S. Brodke ◽  
Jim A. Youssef ◽  
Hans-Joerg Meisel ◽  
Sue Lynn Myhre ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Studies ◽  
Bone Graft ◽  
Spinal Fusion ◽  
Comparative Studies ◽  
Functional Outcomes ◽  
Retrospective Studies ◽  
Synthetic Bone ◽  
Synthetic Bone Graft ◽  
Bone Graft Substitutes

The purpose of this review was to compare the efficacy and safety of synthetic bone graft substitutes versus autograft or allograft for the treatment of lumbar and cervical spinal degenerative diseases. Multiple major medical reference databases were searched for studies that evaluated spinal fusion using synthetic bone graft substitutes (either alone or with an autograft or allograft) compared with autograft and allograft. Randomized controlled trials (RCT) and cohort studies with more than 10 patients were included. Radiographic fusion, patient-reported outcomes, and functional outcomes were the primary outcomes of interest. The search yielded 214 citations with 27 studies that met the inclusion criteria. For the patients with lumbar spinal degenerative disease, data from 19 comparative studies were included: 3 RCTs, 12 prospective, and 4 retrospective studies. Hydroxyapatite (HA), HA+collagen, β-tricalcium phosphate (β-TCP), calcium sulfate, or polymethylmethacrylate (PMMA) were used. Overall, there were no differences between the treatment groups in terms of fusion, functional outcomes, or complications, except in 1 study that found higher rates of HA graft absorption. For the patients with cervical degenerative conditions, data from 8 comparative studies were included: 4 RCTs and 4 cohort studies (1 prospective and 3 retrospective studies). Synthetic grafts included HA, β-TCP/HA, PMMA, and biocompatible osteoconductive polymer (BOP). The PMMA and BOP grafts led to lower fusion rates, and PMMA, HA, and BOP had greater risks of graft fragmentation, settling, and instrumentation problems compared with iliac crest bone graft. The overall quality of evidence evaluating the potential use and superiority of the synthetic biological materials for lumbar and cervical fusion in this systematic review was low or insufficient, largely due to the high potential for bias and small sample sizes. Thus, definitive conclusions or recommendations regarding the use of these synthetic materials should be made cautiously and within the context of the limitations of the evidence.

A Novelty of Synthetic Hydroxyapatite from Cockle Shell and Characterization

2015 ◽  
Vol 1087 ◽  
pp. 429-433 ◽  
Author(s):  
Rusnah Mustaffa ◽  
Mohd Reusmaazran Mohd Yusof ◽  
Yusof Abdullah
Keyword(s):  
Bone Graft ◽  
Bone Repair ◽  
Artificial Bone ◽  
Synthetic Bone ◽  
Potential Source ◽  
Mineral Constituent ◽  
Bone Graft Substitutes ◽  
Synthetic Hydroxyapatite ◽  
Anadara Granosa ◽  
Cockle Shell

In Malaysia recently, it was found that cockle shell (Anadara granosa) is a potential source of biomaterial for bone repair. It is the most abundant sea species cultured in Malaysia. A possible advantage of using cockle shell as a biomaterial is that they may act as an antilog of calcium carbonate. Malaysian Nuclear Agency took this challenge to develop synthetic bone graft from natural cockle shell. To date, the artificial bone graft substitutes developed from hydroxyapatite (Ca10(PO4)6(OH)2) a bio ceramic is similar to the mineral constituent of human bone. The structure and the composition of hydroxyapatite (HA) are similar to the mineral phase of bone and, its bioactivity and biocompatibility makes it a preferred bone graft.

Mandible reconstruction and autogenous frozen bone graft: Experimental study on rats

Microsurgery ◽  
2001 ◽  
Vol 21 (4) ◽  
pp. 131-134 ◽  
Author(s):  
Cristina Garusi ◽  
Luca Calabrese ◽  
Gioacchino Giugliano ◽  
Giovanni Mazzarol ◽  
Stefano Podrecca ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Graft ◽  
Mandible Reconstruction ◽  
Frozen Bone
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