Design of a constant force clamp and estimation of molecular motor motion using modern control approach

Author(s):  
Subhrajit Roychowdhury ◽  
Shreyas Bhaban ◽  
Srinivasa Salapaka ◽  
Murti Salapaka
2013 ◽  
Vol 103 (15) ◽  
pp. 153703 ◽  
Author(s):  
Subhrajit Roychowdhury ◽  
Tanuj Aggarwal ◽  
Srinivasa Salapaka ◽  
Murti V. Salapaka

IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 95823-95831 ◽  
Author(s):  
Usman Javaid ◽  
Adeel Mehmood ◽  
Ali Arshad ◽  
Fahad Imtiaz ◽  
Jamshed Iqbal

1993 ◽  
Vol 115 (4) ◽  
pp. 673-678 ◽  
Author(s):  
R. Shoureshi ◽  
L. Brackney ◽  
N. Kubota ◽  
G. Batta

Active noise control systems currently in use and/or described in the research literature are typically based on adaptive signal processing theory or, equivalently, adaptive feedforward control theory. This paper presents a modern control approach to the problem of active noise cancellation in a three-dimensional space. The controller is designed based on a direct self-tuning regulator. Two forms of adaptive control, namely, pole placement and minimum variance controls are considered and compared in simulation. An implementation of the adaptive minimum variance controller is used to successfully attenuate a harmonic disturbance in a laboratory setting.


2019 ◽  
Author(s):  
Josh E. Baker

AbstractMolecular motors are enzymes that perform work (F · x) when they move along a track a distance x against a constant force F. This work is performed through intermediate chemical steps in a motor’s ATPase reaction cycle, each step having a free energy change associated with it that is a sum of chemical, Δµchem, and mechanical, Δµext, potentials. Defining Δµext is fundamental to our understanding of how molecular motors work, yet after decades of study the definition of Δµext remains disputed. Some postulate that Δµext is a function of both F and x, while others assume that Δµext is a function of neither F nor x, and still others argue that Δµext is a function of F but not x. Here we evaluate these models and conclude that only the latter – a mechanochemical model proposed by A.V. Hill in the 1930’s – describes molecular motor mechanochemistry.


1996 ◽  
Vol 64 (4) ◽  
pp. 663-677 ◽  
Author(s):  
A. HAMMAD ◽  
E. JONCKHEERE ◽  
C.-Y. CHENG ◽  
S. BHAJEKAR ◽  
C.-C. CHIEN

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