Young's modulus measurements of soft tissues with application to elasticity imaging

1996 ◽  
Vol 43 (1) ◽  
pp. 191-194 ◽  
Author(s):  
E.J. Chen ◽  
J. Novakofski ◽  
W.K. Jenkins ◽  
W.D. O'Brien
Keyword(s):  
Young’S Modulus ◽  
Soft Tissues ◽  
Young's Modulus ◽  
Elasticity Imaging

scholarly journals Developing a Quantifying Device for Soft Tissue Material Prop-Erties around Lumbar Spines

Biosensors ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 67
Author(s):  
Song Joo Lee ◽  
Yong-Eun Cho ◽  
Kyung-Hyun Kim ◽  
Deukhee Lee
Keyword(s):  
Lumbar Spine ◽  
Soft Tissue ◽  
Young’S Modulus ◽  
Viscoelastic Properties ◽  
Soft Tissues ◽  
Young's Modulus ◽  
Strain Curve ◽  
Stress And Strain ◽  
Commercial Device ◽  
Tissue Material

Knowing the material properties of the musculoskeletal soft tissue could be important to develop rehabilitation therapy and surgical procedures. However, there is a lack of devices and information on the viscoelastic properties of soft tissues around the lumbar spine. The goal of this study was to develop a portable quantifying device for providing strain and stress curves of muscles and ligaments around the lumbar spine at various stretching speeds. Each sample was conditioned and applied for 20 repeatable cyclic 5 mm stretch-and-relax trials in the direction and perpendicular direction of the fiber at 2, 3 and 5 mm/s. Our device successfully provided the stress and strain curve of the samples and our results showed that there were significant effects of speed on the young’s modulus of the samples (p < 0.05). Compared to the expensive commercial device, our lower-cost device provided comparable stress and strain curves of the sample. Based on our device and findings, various sizes of samples can be measured and viscoelastic properties of the soft tissues can be obtained. Our portable device and approach can help to investigate young’s modulus of musculoskeletal soft tissues conveniently, and can be a basis for developing a material testing device in a surgical room or various lab environments.

Young's modulus reconstruction for elasticity imaging of deep venous thrombosis: animal studies

2004 ◽  
Author(s):  
Salavat R. Aglyamov ◽  
Hua Xie ◽  
Kang Kim ◽  
Jonathan M. Rubin ◽  
Matthew O'Donnell ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Young’S Modulus ◽  
Animal Studies ◽  
Young's Modulus ◽  
Elasticity Imaging

Reconstructing Young’s Modulus Distributions within Soft Tissues From Freehand Elastograms

2006 ◽  
pp. 469-476 ◽  
Author(s):  
M. M. Doyley ◽  
J. C. Bamber ◽  
P. M. Meaney ◽  
F. G. Fuechsel ◽  
N. L. Bush ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Soft Tissues ◽  
Young's Modulus

scholarly journals Model-Based Reconstructive Elasticity Imaging Using Ultrasound

2007 ◽  
Vol 2007 ◽  
pp. 1-11 ◽  
Author(s):  
Salavat R. Aglyamov ◽  
Andrei R. Skovoroda ◽  
Hua Xie ◽  
Kang Kim ◽  
Jonathan M. Rubin ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Young's Modulus ◽  
Strain Tensor ◽  
Surrounding Tissue ◽  
Imaging Method ◽  
Axial Component ◽  
Elasticity Imaging ◽  
Liver Hemangioma ◽  
Model Based ◽  
Tissue Motion

Elasticity imaging is a reconstructive imaging technique where tissue motion in response to mechanical excitation is measured using modern imaging systems, and the estimated displacements are then used to reconstruct the spatial distribution of Young's modulus. Here we present an ultrasound elasticity imaging method that utilizes the model-based technique for Young's modulus reconstruction. Based on the geometry of the imaged object, only one axial component of the strain tensor is used. The numerical implementation of the method is highly efficient because the reconstruction is based on an analytic solution of the forward elastic problem. The model-based approach is illustrated using two potential clinical applications: differentiation of liver hemangioma and staging of deep venous thrombosis. Overall, these studies demonstrate that model-based reconstructive elasticity imaging can be used in applications where the geometry of the object and the surrounding tissue is somewhat known and certain assumptions about the pathology can be made.

Softness Measurement Technics of Human Skin by Indentation Devices Imitating Palpation

2013 ◽  
Author(s):  
Atsushi Sakuma
Keyword(s):  
Young’S Modulus ◽  
Human Skin ◽  
Soft Tissues ◽  
Young's Modulus ◽  
Finite Thickness ◽  
The Body ◽  
Ultraviolet Rays ◽  
Spherical Indentation ◽  
Measurement Technology ◽  
Human Face

The characteristics of human skin are easily changed by the states of the body because it is very sensitive to environmental transformation. And the development of the condition measurement technology of human skin is very important for improvement in QOL because it reflects body condition. Then, various devices for the condition measurement of human skin had been developed but there was no technique which can evaluate the skin by objective parameter easily. In this paper, spherical indentation testing is studied to evaluate the dimension and rigidity of thin soft-tissues like human skin. Here, the Hertz contact theory is functionally expanded to evaluate indentations for the thin tissues. In the expansions, the technique used for evaluating the thickness of finite specimens is first explained by analyzing the experimental results of indentations. Then, the Young’s modulus of the tissue with finite thickness is theoretically derived by defining an equivalent indentation strain for the analysis of the indentation process. The expansions are examined to evaluate its reliability by applying them to measure Young’s modulus of some thin materials. Furthermore, this technology is applied to the elasticity investigation of the human skin. Especially, the measurement results of elasticity characteristics of the skin of human face are shown as the first report. The influences of sex and ultraviolet rays and so on are discussed to reveal the mechanics of human skin in this report. Moreover, it is discussed about the validity of the device which measures the elasticity of the skin of human face.

Tissue-Mimicking Oil-in-Gelatin Dispersions for Use in Heterogeneous Elastography Phantoms

2003 ◽  
Vol 25 (1) ◽  
pp. 17-38 ◽  
Author(s):  
E.L. Madsen ◽  
G.R. Frank ◽  
T.A. Krouskop ◽  
T. Varghese ◽  
F. Kallel ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Soft Tissues ◽  
Young's Modulus ◽  
Relaxation Times ◽  
Ultrasound Elastography ◽  
Safflower Oil ◽  
Mr Elastography ◽  
Volume Percent ◽  
Transverse Relaxation ◽  
Oil Concentration

A ten-month study is presented of materials for use in heterogeneous elastography phantoms. The materials consist of gelatin with or without a suspension of microscopic safflower oil droplets. The highest volume percent of oil in the materials is 50%. Thimerosal acts as a preservative. The greater the safflower oil concentration, the lower the Young's modulus. Elastographic data for heterogeneous phantoms, in which the only variable is safflower oil concentration, demonstrate stability of inclusion geometry and elastic strain contrast. Young's modulus ratios (elastic contrasts) producible in a heterogeneous phantom are as high as 2.7. The phantoms are particularly useful for ultrasound elastography. They can also be employed in MR elastography, although the highest achievable ratio of longitudinal to transverse relaxation times is considerably less than is the case for soft tissues.

scholarly journals Quantitative Imaging of Young’s Modulus of Soft Tissues from Ultrasound Water Jet Indentation: A Finite Element Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Min-Hua Lu ◽  
Rui Mao ◽  
Yin Lu ◽  
Zheng Liu ◽  
Tian-Fu Wang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Finite Element ◽  
Soft Tissue ◽  
Young’S Modulus ◽  
Soft Tissues ◽  
Young's Modulus ◽  
Quantitative Imaging ◽  
Element Model ◽  
Water Jet ◽  
High Frequency Ultrasound

Indentation testing is a widely used approach to evaluate mechanical characteristics of soft tissues quantitatively. Young’s modulus of soft tissue can be calculated from the force-deformation data with known tissue thickness and Poisson’s ratio using Hayes’ equation. Our group previously developed a noncontact indentation system using a water jet as a soft indenter as well as the coupling medium for the propagation of high-frequency ultrasound. The novel system has shown its ability to detect the early degeneration of articular cartilage. However, there is still lack of a quantitative method to extract the intrinsic mechanical properties of soft tissue from water jet indentation. The purpose of this study is to investigate the relationship between the loading-unloading curves and the mechanical properties of soft tissues to provide an imaging technique of tissue mechanical properties. A 3D finite element model of water jet indentation was developed with consideration of finite deformation effect. An improved Hayes’ equation has been derived by introducing a new scaling factor which is dependent on Poisson’s ratiosv, aspect ratioa/h(the radius of the indenter/the thickness of the test tissue), and deformation ratiod/h. With this model, the Young’s modulus of soft tissue can be quantitatively evaluated and imaged with the error no more than 2%.

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