An automatic registration method for frameless stereotaxy, image guided surgery, and enhanced reality visualization

1996 ◽  
Vol 15 (2) ◽  
pp. 129-140 ◽  
Author(s):  
W.E.L. Grimson ◽  
G.J. Ettinger ◽  
S.J. White ◽  
T. Lozano-Perez ◽  
W.M. Wells ◽  
...  
Keyword(s):  
Image Guided Surgery ◽  
Frameless Stereotaxy ◽  
Automatic Registration ◽  
Registration Method ◽  
Guided Surgery ◽  
Image Guided ◽  
Enhanced Reality

S203 – The STAMP Registration for Image-guided Otologic Surgery

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P143-P144
Author(s):  
Nozomu Matsumoto ◽  
Jaesung Hong ◽  
Hashizume Makoto ◽  
Shizuo Komune
Keyword(s):  
Surgical Navigation ◽  
Phantom Study ◽  
Image Guided Surgery ◽  
Registration Method ◽  
Guided Surgery ◽  
Otologic Surgery ◽  
Image Guided ◽  
Registration Errors ◽  
Preoperative Procedures ◽  
New System

Objectives 1) Develop a less invasive but accurate enough registration strategy for otological surgical navigation. 2) Evaluate the new system in phantom study. 3) Evaluate the new system in cochlear implant surgeries. Methods A new registration method was developed for otologic surgery. Previously, the registration for accurate image-guided surgery often required invasive fiducial markers attached on patient's bone. We utilized the template of the bone surface to transfer the pre-made virtual bone-anchored markers to the patient's bone intraoperatively and eliminated the necessity for preoperative marker positioning or preoperative additional CT scan. Results We tested this Surface Template-Assisted Marker Positioning (STAMP) method using 5 temporal bone replicas, and in 5 ear surgeries (2 cochlear implants, 3 translabyrinthine acoustic neuroma surgeries) to investigate whether this method improves, or at least retains, the accuracy of image- guided surgery (IGS). The fiducial registration errors and target registration errors in the phantom study was ∼0.7 mm and ∼1.5 mm, respectively. The target registration errors in replicas were always less than 2 mm. In actual ear surgeries the fiducial registration errors were ∼0.6 mm and the target registration errors were less than 2 mm in 4 of 5 surgeries. All patients received successful cochlear implantation or tumor removal. Conclusions The new method reduced the preoperative procedures for patients but did not reduce the accuracy of the surgical navigation. Our method would be a useful IGS method in the field of otology where both accuracy and non-invasiveness are required.

Three-Dimensional Localization: From Image-Guided Surgery to Information-Guided Therapy

Methods ◽  
2001 ◽  
Vol 25 (2) ◽  
pp. 186-200 ◽  
Author(s):  
Richard D. Bucholz ◽  
Kurt R. Smith ◽  
Keith A. Laycock ◽  
Leslie L. McDurmont
Keyword(s):  
Three Dimensional ◽  
Image Guided Surgery ◽  
Guided Surgery ◽  
Image Guided ◽  
Guided Therapy

scholarly journals Radiopharmaceutical and Eu3+ doped gadolinium oxide nanoparticles mediated triple-excited fluorescence imaging and image-guided surgery

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Xiaojing Shi ◽  
Caiguang Cao ◽  
Zeyu Zhang ◽  
Jie Tian ◽  
Zhenhua Hu
Keyword(s):  
Fluorescent Probes ◽  
Signal Intensity ◽  
Tumor Imaging ◽  
Tumor Resection ◽  
Optical Signal ◽  
Gadolinium Oxide ◽  
Image Guided Surgery ◽  
Guided Surgery ◽  
Image Guided ◽  
The Impact

AbstractCerenkov luminescence imaging (CLI) is a novel optical imaging technique that has been applied in clinic using various radionuclides and radiopharmaceuticals. However, clinical application of CLI has been limited by weak optical signal and restricted tissue penetration depth. Various fluorescent probes have been combined with radiopharmaceuticals for improved imaging performances. However, as most of these probes only interact with Cerenkov luminescence (CL), the low photon fluence of CL greatly restricted it’s interaction with fluorescent probes for in vivo imaging. Therefore, it is important to develop probes that can effectively convert energy beyond CL such as β and γ to the low energy optical signals. In this study, a Eu3+ doped gadolinium oxide (Gd2O3:Eu) was synthesized and combined with radiopharmaceuticals to achieve a red-shifted optical spectrum with less tissue scattering and enhanced optical signal intensity in this study. The interaction between Gd2O3:Eu and radiopharmaceutical were investigated using 18F-fluorodeoxyglucose (18F-FDG). The ex vivo optical signal intensity of the mixture of Gd2O3:Eu and 18F-FDG reached 369 times as high as that of CLI using 18F-FDG alone. To achieve improved biocompatibility, the Gd2O3:Eu nanoparticles were then modified with polyvinyl alcohol (PVA), and the resulted nanoprobe PVA modified Gd2O3:Eu (Gd2O3:Eu@PVA) was applied in intraoperative tumor imaging. Compared with 18F-FDG alone, intraoperative administration of Gd2O3:Eu@PVA and 18F-FDG combination achieved a much higher tumor-to-normal tissue ratio (TNR, 10.24 ± 2.24 vs. 1.87 ± 0.73, P = 0.0030). The use of Gd2O3:Eu@PVA and 18F-FDG also assisted intraoperative detection of tumors that were omitted by preoperative positron emission tomography (PET) imaging. Further experiment of image-guided surgery demonstrated feasibility of image-guided tumor resection using Gd2O3:Eu@PVA and 18F-FDG. In summary, Gd2O3:Eu can achieve significantly optimized imaging property when combined with 18F-FDG in intraoperative tumor imaging and image-guided tumor resection surgery. It is expected that the development of the Gd2O3:Eu nanoparticle will promote investigation and application of novel nanoparticles that can interact with radiopharmaceuticals for improved imaging properties. This work highlighted the impact of the nanoprobe that can be excited by radiopharmaceuticals emitting CL, β, and γ radiation for precisely imaging of tumor and intraoperatively guide tumor resection.

Image‐guided surgery in otolaryngology: A review of current applications and future directions in head and neck surgery

Head & Neck ◽  
2021 ◽  
Author(s):  
Sarah Y. Bessen ◽  
Xiaotian Wu ◽  
Michael T. Sramek ◽  
Yuan Shi ◽  
David Pastel ◽  
...  
Keyword(s):  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Image Guided Surgery ◽  
Future Directions ◽  
Guided Surgery ◽  
Image Guided
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