Generation of multiple pulses with extremely short pulse repetition interval

2000 ◽  
Vol 28 (5) ◽  
pp. 1382-1385
Author(s):  
K. Takao ◽  
K. Masugata ◽  
K. Yatsui
Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5040
Author(s):  
Silvia Ronda Peñacoba ◽  
Mar Fernández Gutiérrez ◽  
Julio San Román del Barrio ◽  
Francisco Montero de Espinosa

Despite the use of therapeutic ultrasound in the treatment of soft tissue pathologies, there remains some controversy regarding its efficacy. In order to develop new treatment protocols, it is a common practice to carry out in vitro studies in cell cultures before conducting animal tests. The lack of reproducibility of the experimental results observed in the literature concerning in vitro experiments motivated us to establish a methodology for characterizing the acoustic field in culture plate wells. In this work, such acoustic fields are fully characterized in a real experimental configuration, with the transducer being placed in contact with the surface of a standard 12-well culture plate. To study the non-thermal effects of ultrasound on fibroblasts, two different treatment protocols are proposed: long pulse (200 cycles) signals, which give rise to a standing wave in the well with the presence of cavitation (ISPTP max = 19.25 W/cm2), and a short pulse (five cycles) of high acoustic pressure, which produces a number of echoes in the cavity (ISPTP = 33.1 W/cm2, with Pmax = 1.01 MPa). The influence of the acoustic intensity, the number of pulses, and the pulse repetition frequency was studied. We further analyzed the correlation of these acoustic parameters with cell viability, population, occupied surface, and cell morphology. Lytic effects when cavitation was present, as well as mechanotransduction reactions, were observed.


Author(s):  
RUSTAMAJI RUSTAMAJI ◽  
KANIA SAWITRI ◽  
RUDI GUNAWAN

ABSTRAKPingers transmitter berfungsi untuk memancarkan sinyal atau getaran pulsa akustik pada black box. Frekuensi sinyal yang dipancarkan sebesar 37,5 kHz yang dimodulasikan oleh pulsa dengan durasi 10 ms setiap interval 1 second. Modulasi yang digunakan adalah modulasi on off keying. Dalam penelitian ini dibuat perancangan pingers transmitter yang tersusun atas rangkaian osilator, timer, inverter, switch dan rangkaian amplifier. Frekuensi 37,5 kHz tersebut dibangkitkan oleh rangkaian osilator colpitts, sedangkan lebar pulsa dengan durasi 10 ms dan pengulangan pulsa setiap interval 1 second dibangkitkan oleh rangkaian timer. Berdasarkan perancangan yang telah dibuat, output sinyal yang dihasilkan oleh prototipe pingers transmitter tersebut sebesar 37,69 kHz dengan lebar pulsa 9,8 ms setiap interval 1 second.Kata kunci: Black box, pingers transmitter, on off keying. ABSTRACTPingers transmitter is used to emits a signal or pulse of acoustic vibrations  in black box. The frequency of the transmitted signal is 37.5 kHz which is modulated by pulses with a duration of 10 ms every interval 1 second. The modulation that used this research is on off keying modulation. In this research, made the design of pingers transmitter which arrange of the oscillator circuit,timer, inverter, switch, and amplifier circuit. The 37.5 kHz frequency is generated by the colpitts oscillator circuit, while the pulse width with a duration of 10 ms,and each pulse repetition interval of 1 second generated by timer circuit. Based on the design that have made, signal output from the pingers transmitter prototype is 37.69 kHz, with the pulse width 9.8 ms every 1 second interval.Keywords: Black box, pingers transmitter, on off keying.


IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 30126-30134 ◽  
Author(s):  
Zhipeng Ge ◽  
Xian Sun ◽  
Wenjuan Ren ◽  
Wenbin Chen ◽  
Guangluan Xu

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