A highly efficient alpha, beta, gamma-spectrometer with low background

1996 ◽  
Vol 43 (3) ◽  
pp. 1284-1286 ◽  
Author(s):  
L.L. Nagornaya ◽  
O.V. Zelenskaya ◽  
S.V. Budakovsky ◽  
Yu.A. Chichikalyuk
1973 ◽  
Vol 34 (2) ◽  
pp. 162-164
Author(s):  
Yu. A. Surkov ◽  
O. P. Sobornov

2021 ◽  
Author(s):  
Gretchen Meinke ◽  
Nahide Dalda ◽  
Benjamin S Brigham ◽  
Andrew Bohm

Abstract Directed DNA libraries are useful because they focus genetic diversity in the most important regions within a sequence. Ideally, all sequences in such libraries should appear with the same frequency and there should be no significant background from the starting sequence. These properties maximize the number of different sequences that can be screened. Described herein is a method termed SLUPT (Synthesis of Libraries via a dU-containing PCR Template) for generating highly targeted DNA libraries and/or multi-site mutations wherein the altered bases may be widely distributed within a target sequence. This method is highly efficient and modular. Moreover, multiple distinct sites, each with one or more base changes, can be altered in a single reaction. There is very low background from the starting sequence, and SLUPT libraries have similar representation of each base at the positions selected for variation. The SLUPT method utilizes a single stranded dU-containing DNA template that is made by PCR. Synthesis of the template in this way is significantly easier than has been described earlier. A series of oligonucleotide primers that are homologous to the template and encode the desired genetic diversity are extended and ligated in a single reaction to form the mutated product sequence or library. After selective inactivation of the template, only the product library is amplified. There are no restrictions on the spacing of the mutagenic primers except that they cannot overlap.


2019 ◽  
Vol 1060 ◽  
pp. 133-141 ◽  
Author(s):  
Jiaxiang Yin ◽  
Lei Mou ◽  
Mingzhu Yang ◽  
Wenwu Zou ◽  
Chang Du ◽  
...  

Author(s):  
Huilan Liu ◽  
Yushou Song ◽  
Zhaoyang Xie ◽  
Baodong Sun

A low-background gamma spectrometer consists of a high-performance gamma detector and a low-background chamber. It is widely used to monitor the radiation level of the environment and to identify the species of the radiological source. It is especially important for the analysis of the nuclear accident. Usually a high purity Germanium detector (HPGe) is used as a gamma ray detector. In order to enhance the detecting accuracy and sensitivity, it is essential to improve the performance of the gamma detector. In recent years, a clover detector composed of four coaxial HPGe crystals appear and is widely utilized in nuclear physics experimental research. Because of the larger dimensions and segmented structure, it displays outstanding characteristics different from traditional HPGe detectors. With a clover detector as the main detector and the HPLBS1 chamber of ORTEC as the lead chamber, the low-background gamma spectrometer is simulated by the Monte Carlo toolkit GEANT4, where the interaction processes of gamma ray provided by the GEANT4 physics list is used. The detecting performance of the low-background gamma spectrometer such as detecting efficiency and peak-total ratio are given. The results indicate that low-background gamma spectrometer with a clover as the main detector has better characteristic than that with HPGe as a main detector traditionally.


Author(s):  
N. Kamikubota ◽  
H. Ejiri ◽  
T. Shibata ◽  
Y. Nagai ◽  
K. Okada ◽  
...  

2013 ◽  
Vol 16 (3) ◽  
pp. 83-92
Author(s):  
Vinh Quang Trinh ◽  
Loan Thi Hong Truong ◽  
Nhon Van Mai

Genie 2000 version of gamma spectrum processing program, which is being used at Nuclear Physics Department, Physics – Technique Physics Faculty, University of Science is lacked of package for determining radioactivity of sources, also has not been comprehensibly automatic from analysis and process to identification of radioactive isotopes and evaluation of source activity. We have built version 2.1 of VGSpec program to determine source radioactivity. Then, the experiments are carried out to measure cylindrical standard and Marinelli samples by low background gamma spectrometer using HPGe detector, to compare experimental results with ones of the program, as well as assess the accuracy of VGSpec program through ability of determining radioactivity for cylindrical and Marinelli sources.


2010 ◽  
Vol 36 (7) ◽  
pp. 592-594
Author(s):  
A. V. Kopylov ◽  
I. V. Orekhov ◽  
E. P. Petrov ◽  
V. V. Petukhov ◽  
A. A. Tikhonov

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