Breast cancer calcification measurements using direct X-ray detection in a monolithic silicon pixel detector

1994 ◽  
Vol 41 (6) ◽  
pp. 2862-2873 ◽  
Author(s):  
S.I. Parker ◽  
C.J. Kenney ◽  
V.Z. Peterson ◽  
D.M. Ikeda ◽  
F.A. Backus ◽  
...  
1998 ◽  
Author(s):  
Paul Seller ◽  
William J. F. Gannon ◽  
Andrew D. Holland ◽  
Gregory M. Iles ◽  
Barrie G. Lowe ◽  
...  

1995 ◽  
Vol 42 (4) ◽  
pp. 409-412 ◽  
Author(s):  
C. Da Via ◽  
M. Campbell ◽  
E.H.M. Heijne ◽  
P. Middelkamp ◽  
G. Stefanini

2008 ◽  
Vol 53 (4) ◽  
pp. 2185-2191
Author(s):  
Kun-Sik Park ◽  
Jong-Moon Park ◽  
Seong-Wook Yoo ◽  
Yong-Sun Yoon ◽  
Jin-Yeong Kang ◽  
...  

2020 ◽  
pp. 25-31
Author(s):  
M. L. Mazo ◽  
O. E. Jacobs ◽  
O. S. Puchkova ◽  
M. V. Feldsherov ◽  
E. V. Kondratyev

The rate of detection of breast cancer by MRI, while other methods of radiological diagnosis are not sufficiently informative, ranges from 5.2 to 26.3 per cent. Suspicious breast tumors of category BI-RADS 4, 5 show morphological image-guided biopsy verification, in particular MRI with contrast. Purpose. To show the possibilities and features of carrying out MRI-guided vacuum breast biopsy, including after aesthetic breast augmentation. Material and methods. A comprehensive X-ray, ultrasound and MRI examination of 54 women aged between 28 and 70 years with different breast tumors was conducted. Of these, five were detected only by breast MRI with contrast, and were morphologically verified by MRI-guided vacuum aspiration biopsy. Results. 14 of the 54 patients with breast mass were diagnosed with breast cancer and 26 were diagnosed with benign diseases. The effectiveness of comprehensive examination and low-invasive high-tech MRI-guided procedures in early refined screening for breast cancer, including after aesthetic breast augmentation, has been demonstrated. MRI-guided vacuum-assisted breast biopsy is a fast, safe and accurate diagnostic method of morphological verification of suspicious breast tumors that do not have X-ray and ultrasound.


1994 ◽  
Vol 160 (10) ◽  
pp. 617-620 ◽  
Author(s):  
Richard I Harrison ◽  
David C Glenn ◽  
Frederick W Niesche ◽  
William G Patrick ◽  
George Ramsey‐Stewart ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Prihantono Prihantono ◽  
Rizal Irfandi ◽  
Indah Raya

BACKGROUND: With essential metals being studied and developed as anticancer agents, this study aims to explore the anticancer activity of Zn(II) arginine dithiocarbamate in the T47D and fibroblast cell lines. METHOD: The Zn(II) arginine dithiocarbamate complex was prepared by the in situ method and characterized using infra-red spectroscopy, melting point, X-ray fluorescence, and X-ray diffraction instruments. The complex compound was tested for its cytotoxicity to the T47D breast cancer and fibroblast cell lines. RESULTS: The cytotoxicity of the Zn(II) arginine dithiocarbamate complex to the T47D breast cancer cell line obtained IC50 = 3.16 μg/mL, while cisplatin obtained IC50 = 28.18 μg/mL. The cytotoxicity of the Zn(II) arginine dithiocarbamate complex to fibroblast cells obtained IC50 = 8709.63 μg/mL. CONCLUSION: The Zn(II) arginine dithiocarbamate complex has increased active cytotoxicity compared to cisplatin in inducing morphological changes in the T47D breast cancer cell line and is relatively non-toxic to fibroblast cells.


2021 ◽  
Vol 22 (14) ◽  
pp. 7279
Author(s):  
Paulina Natalia Osuchowska ◽  
Przemysław Wachulak ◽  
Wiktoria Kasprzycka ◽  
Agata Nowak-Stępniowska ◽  
Maciej Wakuła ◽  
...  

Understanding cancer cell adhesion could help to diminish tumor progression and metastasis. Adhesion mechanisms are currently the main therapeutic target of TNBC-resistant cells. This work shows the distribution and size of adhesive complexes determined with a common fluorescence microscopy technique and soft X-ray contact microscopy (SXCM). The results presented here demonstrate the potential of applying SXCM for imaging cell protrusions with high resolution when the cells are still alive in a physiological buffer. The possibility to observe the internal components of cells at a pristine and hydrated state with nanometer resolution distinguishes SXCM from the other more commonly used techniques for cell imaging. Thus, SXCM can be a promising technique for investigating the adhesion and organization of the actin cytoskeleton in cancer cells.


AIP Advances ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 025315
Author(s):  
Chaosheng Wu ◽  
Xuanang Huang ◽  
Yongguang Xiao ◽  
Zheng Li

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