Drug-specific /sup 19/F NMR and dynamic /sup 18/F PET imaging of the cytostatic agent 5-fluorouracil

1994 ◽  
Vol 41 (6) ◽  
pp. 2856-2861 ◽  
Author(s):  
M.E. Bellemann ◽  
G. Brix ◽  
U. Haberkorn ◽  
H.J. Ostertag ◽  
W.J. Lorenz
Keyword(s):  
Pet Imaging ◽  
Cytostatic Agent ◽  
19 F Nmr

Alterations in regional decreased cerebral blood flow in patients with irritable bowel syndrome-A PET imaging study

2001 ◽  
Vol 120 (5) ◽  
pp. A637-A637
Author(s):  
Y RINGEL ◽  
D DROSSMAN ◽  
T TURKINGTON ◽  
B BRADSHAW ◽  
R COLEMAN ◽  
...  
Keyword(s):  
Blood Flow ◽  
Irritable Bowel Syndrome ◽  
Cerebral Blood Flow ◽  
Pet Imaging ◽  
Imaging Study ◽  
Irritable Bowel

PET imaging of 5-HT1A receptors in late-life depression: Relationship to treatment response

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S323-S323
Author(s):  
Carolyn C Meltzer ◽  
Julie C Price ◽  
Scott K Ziolko ◽  
Chester A Mathis ◽  
Lisa A Weissfeld ◽  
...  
Keyword(s):  
Treatment Response ◽  
Pet Imaging ◽  
Late Life ◽  
Late Life Depression

Post-radiosynovectomy 90Y-PET imaging

2011 ◽  
Vol 50 (04) ◽  
pp. N39-N39 ◽  
Author(s):  
H. W. E. Prechtel ◽  
F. A. Verburg ◽  
K. J. Dautzenberg ◽  
F. M. Mottaghy ◽  
F. F. Behrendt ◽  
...  
Keyword(s):  
Pet Imaging ◽  
90Y Pet

PET/CT

2005 ◽  
Vol 44 (S 01) ◽  
pp. S51-S57 ◽  
Author(s):  
T. Beyer ◽  
G. Brix
Keyword(s):  
Diagnostic Accuracy ◽  
Radiation Exposure ◽  
Dose Reduction ◽  
Pet Imaging ◽  
Clinical Studies ◽  
Review Article ◽  
Whole Body ◽  
High Radiation ◽  
Radiation Burden ◽  
Pet Ct

Summary:Clinical studies demonstrate a gain in diagnostic accuracy by employing combined PET/CT instead of separate CT and PET imaging. However, whole-body PET/CT examinations result in a comparatively high radiation burden to patients and thus require a proper justification and optimization to avoid repeated exposure or over-exposure of patients. This review article summarizes relevant data concerning radiation exposure of patients resulting from the different components of a combined PET/CT examination and presents different imaging strategies that can help to balance the diagnostic needs and the radiation protection requirements. In addition various dose reduction measures are discussed, some of which can be adopted from CT practice, while others mandate modifications to the existing hardand software of PET/CT systems.

Limitations of dual time point FDG-PET imaging in the evaluation of focal abdominal lesions

2004 ◽  
Vol 43 (05) ◽  
pp. 143-149 ◽  
Author(s):  
N. Hamscho ◽  
C. Menzel ◽  
L. Neuss ◽  
A. F. Kovács ◽  
F. Grünwald ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Malignant Tumors ◽  
Standardized Uptake Value ◽  
Delayed Imaging ◽  
Ct Guided ◽  
Fdg Uptake ◽  
Diagnostic Potential ◽  
Dual Time Point ◽  
Abdominal Lesions ◽  
Time Point

Summary:Aim: For the evaluation of the diagnostic potential of dual time point FDG positron emission tomography (PET) in patients with suspicious focal abdominal up-take, dual time point PET imaging was compared with clinical findings. Patients, methods: In a prospective study, 56 patients exhibiting a solitary suspicious, intense abdominal FDG uptake, underwent dual time point PET imaging for staging or restaging of different malignant tumors, maximal standardized uptake value (SUVmax) measurements included. The first acquisition was started 64.8 ± 19.5, the second 211.3 ± 52.5 min after FDG injection. The final diagnosis based on CT or MRT imaging and a follow-up period of 12.6 ± 2.8 months. Additionally, colonoscopy was done in 6 patients. In another 6 patients histopathology was obtained from CT guided biopsy. Results: Malignant focal abdominal lesions with a SUVmax <2.5 (n = 4) showed an uptake increase of ≥30%. In the remaining malignant cases with an uptake of ≥2.5 (n = 11), up-take increased in 64% and decreased in 36%. Malignant lesions showing FDG uptake decrease (n = 4) had an initial SUVmax value ≥2.5 and remained with a SUVmax ≥2.5 in the second imaging. In benign lesions with an initial SUVmax ≥2.5 (n = 31), the uptake increased in 17 patients (55%) and decreased in 14 patients (45%). All lesions which changed configuration (33%) were confirmed as benign (n = 5). Conclusion: Using dual time point PET abdominal lesions show a very hetergenous uptake pattern regardless of their dignity. Malignancy can only be reliably excluded in lesions which change their configuration and in lesions with an initial SUVmax value <2.5 combined with an SUV decrease in the delayed imaging. Particularly abdominal lesions which show an initial SUVmax ≥2.5 combined with a SUV increase in the delayed imaging are suspicious for malignancy and need further clarification.

Perfusion-Phase 18 F-PI-2620 Tau-PET Imaging as a Surrogate Marker of Neuronal Injury

2020 ◽  
Author(s):  
L Beyer ◽  
A Nitschmann ◽  
H Barthel ◽  
T van Eimeren ◽  
M Unterrainer ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Surrogate Marker ◽  
Neuronal Injury ◽  
Tau Pet ◽  
Tau Pet Imaging
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