Chronic neural stimulation with thin-film, iridium oxide electrodes

2000 ◽  
Vol 47 (7) ◽  
pp. 911-918 ◽  
Author(s):  
J.D. Weiland ◽  
D.J. Anderson
Author(s):  
Terence Mittmann ◽  
Thomas Szyjka ◽  
Hsain Alex ◽  
Marian Cosmin Istrate ◽  
Patrick D. Lomenzo ◽  
...  

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1433
Author(s):  
Esther Tanumihardja ◽  
Douwe S. de Bruijn ◽  
Rolf H. Slaats ◽  
Wouter Olthuis ◽  
Albert van den Berg

A ruthenium oxide (RuOx) electrode was used to monitor contractile events of human pluripotent stem cells-derived cardiomyocytes (hPSC-CMs) through electrical impedance spectroscopy (EIS). Using RuOx electrodes presents an advantage over standard thin film Pt electrodes because the RuOx electrodes can also be used as electrochemical sensor for pH, O2, and nitric oxide, providing multisensory functionality with the same electrode. First, the EIS signal was validated in an optically transparent well-plate setup using Pt wire electrodes. This way, visual data could be recorded simultaneously. Frequency analyses of both EIS and the visual data revealed almost identical frequency components. This suggests both the EIS and visual data captured the similar events of the beating of (an area of) hPSC-CMs. Similar EIS measurement was then performed using the RuOx electrode, which yielded comparable signal and periodicity. This mode of operation adds to the versatility of the RuOx electrode’s use in in vitro studies.


Author(s):  
Ryan Q. Rudy ◽  
Kyle M. Grove ◽  
Manuel Rivas ◽  
Jonathon Guerrier ◽  
Cory Cress ◽  
...  

2017 ◽  
Vol 70 (9) ◽  
pp. 1016 ◽  
Author(s):  
Alexander R. Harris ◽  
Antonio G. Paolini

Iridium oxide is routinely used for bionic applications owing to its high charge injection capacity. The electrode impedance at 1 kHz is typically reported to predict neural recording performance. In this article, the impedance of activated iridium oxide films (AIROFs) has been examined. The impedance of unactivated iridium electrodes was half that of platinum electrodes of similar geometry, indicating some iridium oxide was present on the electrode surface. A two time constant equivalent circuit was used to model the impedance of activated iridium. The impedance at low and intermediate frequencies decreased with increasing number of activation pulses and total activation charge. The impedance at 12 Hz correlated with the steady-state diffusion electroactive area. The impedance at 12 Hz also correlated with the charge density of the electrode. The high charge density and low impedance of AIROFs may provide improved neural stimulation and recording properties compared with typically used platinum electrodes.


1999 ◽  
Vol 38 (Part 2, No. 10A) ◽  
pp. L1128-L1130 ◽  
Author(s):  
Seon Yong Cha ◽  
Hee Chul Lee

Author(s):  
Naser Pour Aryan ◽  
Christian Brendler ◽  
Viola Rieger ◽  
Steffen Kibbel ◽  
Alex Harscher ◽  
...  

2017 ◽  
Vol 69 (1) ◽  
pp. 76-88 ◽  
Author(s):  
Y. Seguí Femenias ◽  
U. Angst ◽  
B. Elsener

2019 ◽  
Vol 788 ◽  
pp. 30-35
Author(s):  
Xiangyu Sun ◽  
Dongdong Gong ◽  
Liqiang Xu ◽  
Yicheng Wang ◽  
Feng Qin ◽  
...  

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