scholarly journals Determination of the functional elements within the vacuolar targeting signal of barley lectin.

1993 ◽  
Vol 5 (5) ◽  
pp. 587-596 ◽  
Author(s):  
J E Dombrowski ◽  
M R Schroeder ◽  
S Y Bednarek ◽  
N V Raikhel
1993 ◽  
Vol 5 (5) ◽  
pp. 587
Author(s):  
James E. Dombrowski ◽  
Martin R. Schroeder ◽  
Sebastian Y. Bednarek ◽  
Natasha V. Raikhel

Author(s):  
Mariusz Wesołowski ◽  
Krzysztof Blacha ◽  
Piotr Barszcz

An important factor that affects the safety of flight operations is the proper management of airports, which should be based on the obtained in systematic way information about the state of the surface of the functional elements. One of the characteristic quantities of the technical condition of airport indicator is the assessment of the degree of degradation. It should be noted that the degradation is a slow process extended in time and is the lowering of the properties of the structure by external influences, which in turn generates the changes in their structure. Rating degrade surface should be conducted periodically, which period shall be estimated on the basis of information obtained from the process of the operation of aircraft. Demotions surface is determined on the basis of the type and quantity survey found damage and made repairs. The basis for evaluating the degree of surface degradation is to obtain data from surveys conducted using the method of visual and inventory of them. Research by visual method, despite its apparent simplicity, it is difficult to implement. Qualification of damage or repairs to the appropriate group is often not clear, and therefore the inventory process is described in the documentation of quality management system. The multi-criteria analysis is a method of evaluating the weighted supporting estimating the degree of degradation airfield pavements based on data obtained through inspections performed. Its base is included in the determination of a number of criteria for the selection variant, taking into account different weights to each criterion. The value of the indicator characterizing the degree of surface degradation in relation to estimated criteria allows you to schedule the necessary resources needed to carry out repairs and rational planning of repairs.


1990 ◽  
Vol 111 (2) ◽  
pp. 361-368 ◽  
Author(s):  
L A Valls ◽  
J R Winther ◽  
T H Stevens

The amino-terminal propeptide of carboxypeptidase Y (CPY) is necessary and sufficient for targeting this glycoprotein to the vacuole of Saccharomyces cerevisiae. A 16 amino acid stretch of the propeptide was subjected to region-directed mutagenesis using randomized oligonucleotides. Mutations altering any of four contiguous amino acids, Gln-Arg-Pro-Leu, resulted in secretion of the encoded CPY precursor (proCPY), demonstrating that these residues form the core of the vacuolar targeting signal. Cells that simultaneously synthesize both wild-type and sorting-defective forms of proCPY efficiently sort and deliver only the wild-type molecule to the vacuole. These results indicate that the PRC1 missorting mutations are cis-dominant, implying that the mutant forms of proCPY are secreted as a consequence of failing to interact with the sorting apparatus, rather than a general poisoning of the vacuolar protein targeting system.


2021 ◽  
Vol 98 ◽  
pp. 03011
Author(s):  
Monica-Nataliia Wagner ◽  
Umeda Ovezova

Universities are important structural and functional elements of megalopolises, they carry out professional training of specialists for various spheres of society; in addition, they are scientific and cultural centers. Nowadays the issues of education improvement, in particular, its spatial organization, are especially important. In this regard, this work analyzes international experience of spatial organization of university campuses in urban structure, including determination of major forms of territorial-spatial organization of university campuses and approaches to territorial-spatial development of campuses both in urban structure and in the campus territory.


1991 ◽  
pp. 575-582
Author(s):  
Maarten J. Chrispeels ◽  
Craig D. Dickinson ◽  
Brian W. Tague ◽  
Dale C. Hunt ◽  
Antje von Schaewen

2019 ◽  
Vol 67 ◽  
pp. 02010
Author(s):  
Tetyana Tymofyeyeva ◽  
Natalia Gritsenko ◽  
Yujia Myroshychenko ◽  
Iryna Motsna

It is found that the railway economic safety system shall be formed taking into consideration current social changes in the society. There is the comprehensive approach to the formation of railway economic safety schemes. It is found that railway economic safety enforcement shall be the continuous cyclic process to be regularly improved. There is the scheme of execution sequence of railway economic safety management. It is found that while determining railway economic safety, in whole or in part, of each element, quantitative and qualitative evaluation methods shall be used and combined. There is the calculation of railway economic safety based on the determination of aggregate criterion. It is found that the selection of figures upon certain functional elements shall be made based on any threats.


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