scholarly journals Mass Spectrometry Imaging with Single-Cell Resolution: Spatial Distribution of Lipids in Cotton Seeds

2012 ◽  
Vol 24 (2) ◽  
pp. 371-371 ◽  
Author(s):  
Jennifer Mach
Keyword(s):  
Mass Spectrometry ◽  
Spatial Distribution ◽  
Single Cell ◽  
Mass Spectrometry Imaging ◽  
Cotton Seeds

scholarly journals Unveiling the spatial distribution of aflatoxin B1 and plant defense metabolites in maize using AP‐SMALDI mass spectrometry imaging

2021 ◽  
Author(s):  
Laura Righetti ◽  
Dhaka Ram Bhandari ◽  
Enrico Rolli ◽  
Sara Tortorella ◽  
Renato Bruni ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Spatial Distribution ◽  
Plant Defense ◽  
Aflatoxin B1 ◽  
Mass Spectrometry Imaging

scholarly journals Spermidine and other functional phytochemicals in soybean seeds: Spatial distribution as visualized by mass spectrometry imaging

2019 ◽  
Vol 8 (1) ◽  
pp. 675-682 ◽  
Author(s):  
Tatsuya Sagara ◽  
Dhaka Ram Bhandari ◽  
Bernhard Spengler ◽  
Johann Vollmann
Keyword(s):  
Mass Spectrometry ◽  
Spatial Distribution ◽  
Mass Spectrometry Imaging ◽  
Soybean Seeds

scholarly journals Mass spectrometry imaging: linking molecule profiles to tissue spatial distribution

2013 ◽  
Vol 10 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Hassan Dihazi ◽  
Rainer Bohrer ◽  
Olaf Jahn ◽  
Christof Lenz ◽  
Andrzej Majcherczyk ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Spatial Distribution ◽  
Mass Spectrometry Imaging

scholarly journals Morphometric Cell Classification for Single‐Cell MALDI‐Mass Spectrometry Imaging

2020 ◽  
Vol 59 (40) ◽  
pp. 17447-17450 ◽  
Author(s):  
Klára Ščupáková ◽  
Frédéric Dewez ◽  
Axel K. Walch ◽  
Ron M. A. Heeren ◽  
Benjamin Balluff
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Mass Spectrometry Imaging ◽  
Maldi Mass Spectrometry ◽  
Cell Classification ◽  
Maldi Mass Spectrometry Imaging

scholarly journals Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact

2011 ◽  
Vol 8 (5) ◽  
pp. 591-604 ◽  
Author(s):  
Kristin J Boggio ◽  
Emmanuel Obasuyi ◽  
Ken Sugino ◽  
Sacha B Nelson ◽  
Nathalie YR Agar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Mass Spectrometry Imaging ◽  
Maldi Mass Spectrometry ◽  
Clinical Impact ◽  
Recent Advances ◽  
Potential Clinical Impact ◽  
Maldi Mass Spectrometry Imaging

Metabolic Imaging at the Single-Cell Scale: Recent Advances in Mass Spectrometry Imaging

2019 ◽  
Vol 12 (1) ◽  
pp. 201-224 ◽  
Author(s):  
Ian S. Gilmore ◽  
Sven Heiles ◽  
Cornelius L. Pieterse
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Mass Spectrometry Imaging ◽  
Secondary Ion Mass Spectrometry ◽  
Cell Types ◽  
Metabolic Imaging ◽  
Spatially Resolved ◽  
Recent Advances ◽  
Challenges And Opportunities ◽  
Future Challenges

There is an increasing appreciation that every cell, even of the same type, is different. This complexity, when additionally combined with the variety of different cell types in tissue, is driving the need for spatially resolved omics at the single-cell scale. Rapid advances are being made in genomics and transcriptomics, but progress in metabolomics lags. This is partly because amplification and tagging strategies are not suited to dynamically created metabolite molecules. Mass spectrometry imaging has excellent potential for metabolic imaging. This review summarizes the recent advances in two of these techniques: matrix-assisted laser desorption ionization (MALDI) and secondary ion mass spectrometry (SIMS) and their convergence in subcellular spatial resolution and molecular information. The barriers that have held back progress such as lack of sensitivity and the breakthroughs that have been made including laser-postionization are highlighted as well as the future challenges and opportunities for metabolic imaging at the single-cell scale.

Sign in / Sign up

Export Citation Format

Share Document