scholarly journals Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis

2013 ◽  
Vol 25 (5) ◽  
pp. 1657-1673 ◽  
Author(s):  
Dongqin Chen ◽  
Gang Xu ◽  
Weijiang Tang ◽  
Yanjun Jing ◽  
Qiang Ji ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Transcription Factors ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Basic Helix Loop Helix ◽  
Helix Loop Helix ◽  
Bzip Transcription Factors ◽  
Reactive Oxygen Species Signaling

scholarly journals Transcriptomic Footprints Disclose Specificity of Reactive Oxygen Species Signaling in Arabidopsis

2006 ◽  
Vol 141 (2) ◽  
pp. 436-445 ◽  
Author(s):  
Ilya Gadjev ◽  
Sandy Vanderauwera ◽  
Tsanko S. Gechev ◽  
Christophe Laloi ◽  
Ivan N. Minkov ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Reactive Oxygen Species Signaling

Reactive Oxygen Species Signaling and Seed Germination

2017 ◽  
pp. 291-306 ◽  
Author(s):  
Prabhakaran Soundararajan ◽  
Abinaya Manivannan ◽  
Byoung Ryong Jeong
Keyword(s):  
Reactive Oxygen Species ◽  
Seed Germination ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Reactive Oxygen Species Signaling

scholarly journals Identification of a Functional Peroxisome Proliferator-Activated Receptor Response Element in the Rat Catalase Promoter

2002 ◽  
Vol 16 (12) ◽  
pp. 2793-2801 ◽  
Author(s):  
Geoffrey D. Girnun ◽  
Frederick E. Domann ◽  
Steven A. Moore ◽  
Mike E. C. Robbins
Keyword(s):  
Reactive Oxygen Species ◽  
Transcription Factors ◽  
Inflammatory Response ◽  
Reactive Oxygen ◽  
Peroxisome Proliferator ◽  
Oxygen Species ◽  
Response Element ◽  
Peroxisome Proliferator Activated Receptor ◽  
Promoter Deletion Analysis

Abstract Peroxisomal proliferator-activated receptor (PPAR)γ has been shown to decrease the inflammatory response via transrepression of proinflammatory transcription factors. However, the identity of PPARγ responsive genes that decrease the inflammatory response has remained elusive. Because generation of the reactive oxygen species hydrogen peroxide (H2O2) plays a role in the inflammatory process and activation of proinflammatory transcription factors, we wanted to determine whether the antioxidant enzyme catalase might be a PPARγ target gene. We identified a putative PPAR response element (PPRE) containing the canonical direct repeat 1 motif, AGGTGA-A-AGTTGA, in the rat catalase promoter. In vitro translated PPARγ and retinoic X receptor-α proteins were able to bind to the catalase PPRE. Promoter deletion analysis revealed that the PPRE was functional, and a heterologous promoter construct containing a multimerized catalase PPRE demonstrated that the PPRE was necessary and sufficient for PPARγ-mediated activation. Treatment of microvascular endothelial cells with PPARγ ligands led to increases in catalase mRNA and activity. These results demonstrate that PPARγ can alter catalase expression; this occurs via a PPRE in the rat catalase promoter. Thus, in addition to transrepression of proinflammatory transcription factors, PPARγ may also be modulating catalase expression, and hence down-regulating the inflammatory response via scavenging of reactive oxygen species.

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