scholarly journals The CHD3 Chromatin Remodeler PICKLE and Polycomb Group Proteins Antagonistically Regulate Meristem Activity in the Arabidopsis Root

2011 ◽  
Vol 23 (3) ◽  
pp. 1047-1060 ◽  
Author(s):  
Ernst Aichinger ◽  
Corina B.R. Villar ◽  
Riccardo Di Mambro ◽  
Sabrina Sabatini ◽  
Claudia Köhler
Keyword(s):  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Chromatin Remodeler ◽  
Arabidopsis Root

Transvection and Silencing of the Scr Homeotic Gene of Drosophila melanogaster

Genetics ◽  
2002 ◽  
Vol 161 (2) ◽  
pp. 733-746
Author(s):  
Jeffrey W Southworth ◽  
James A Kennison
Keyword(s):  
Drosophila Melanogaster ◽  
Chromosomal Aberrations ◽  
Regulatory Element ◽  
Regulatory Elements ◽  
Anomalous Behavior ◽  
Polycomb Group ◽  
Homeotic Gene ◽  
Polycomb Group Proteins ◽  
Sex Combs Reduced ◽  
In Cis

Abstract The Sex combs reduced (Scr) gene specifies the identities of the labial and first thoracic segments in Drosophila melanogaster. In imaginal cells, some Scr mutations allow cis-regulatory elements on one chromosome to stimulate expression of the promoter on the homolog, a phenomenon that was named transvection by Ed Lewis in 1954. Transvection at the Scr gene is blocked by rearrangements that disrupt pairing, but is zeste independent. Silencing of the Scr gene in the second and third thoracic segments, which requires the Polycomb group proteins, is disrupted by most chromosomal aberrations within the Scr gene. Some chromosomal aberrations completely derepress Scr even in the presence of normal levels of all Polycomb group proteins. On the basis of the pattern of chromosomal aberrations that disrupt Scr gene silencing, we propose a model in which two cis-regulatory elements interact to stabilize silencing of any promoter or cis-regulatory element physically between them. This model also explains the anomalous behavior of the Scx allele of the flanking homeotic gene, Antennapedia. This allele, which is associated with an insertion near the Antennapedia P1 promoter, inactivates the Antennapedia P1 and P2 promoters in cis and derepresses the Scr promoters both in cis and on the homologous chromosome.

scholarly journals De novo recruitment of Polycomb-group proteins in Drosophila embryos

Development ◽  
2018 ◽  
Vol 145 (23) ◽  
pp. dev165027 ◽  
Author(s):  
Jumana Alhaj Abed ◽  
Elnaz Ghotbi ◽  
Piao Ye ◽  
Alexander Frolov ◽  
Judith Benes ◽  
...  
Keyword(s):  
De Novo ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Drosophila Embryos
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