scholarly journals Arabidopsis Transcription Factor ELONGATED HYPOCOTYL5 Plays a Role in the Feedback Regulation of Phytochrome A Signaling

2010 ◽  
Vol 22 (11) ◽  
pp. 3634-3649 ◽  
Author(s):  
Jigang Li ◽  
Gang Li ◽  
Shumin Gao ◽  
Cristina Martinez ◽  
Guangming He ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Feedback Regulation ◽  
Phytochrome A

scholarly journals Feedback Regulation of ABA Signaling and Biosynthesis by a bZIP Transcription Factor Targets Drought-Resistance-Related Genes

2016 ◽  
Vol 171 (4) ◽  
pp. 2810-2825 ◽  
Author(s):  
Wei Zong ◽  
Ning Tang ◽  
Jun Yang ◽  
Lei Peng ◽  
Siqi Ma ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Drought Resistance ◽  
Feedback Regulation ◽  
Bzip Transcription Factor ◽  
Aba Signaling

Feedback regulation of the MBF transcription factor by cyclin Cig2

2001 ◽  
Vol 3 (12) ◽  
pp. 1043-1050 ◽  
Author(s):  
José Ayté ◽  
Colleen Schweitzer ◽  
Patrick Zarzov ◽  
Paul Nurse ◽  
James A. DeCaprio
Keyword(s):  
Transcription Factor ◽  
Feedback Regulation

scholarly journals Reciprocal autoregulation by NFI occupancy and ETV1 promotes the developmental expression of dendrite-synapse genes in cerebellar granule neurons

2016 ◽  
Vol 27 (9) ◽  
pp. 1488-1499 ◽  
Author(s):  
Baojin Ding ◽  
John W. Cave ◽  
Paul R. Dobner ◽  
Debra Mullikin-Kilpatrick ◽  
Marina Bartzokis ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Target Genes ◽  
Feedback Regulation ◽  
Developmental Expression ◽  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Cerebellar Granule ◽  
Temporal Gene Expression

Nuclear Factor One (NFI) transcription factors regulate temporal gene expression required for dendritogenesis and synaptogenesis via delayed occupancy of target promoters in developing cerebellar granule neurons (CGNs). Mechanisms that promote NFI temporal occupancy have not been previously defined. We show here that the transcription factor ETV1 directly binds to and is required for expression and NFI occupancy of a cohort of NFI-dependent genes in CGNs maturing in vivo. Expression of ETV1 is low in early postnatal cerebellum and increases with maturation, mirroring NFI temporal occupancy of coregulated target genes. Precocious expression of ETV1 in mouse CGNs accelerated onset of expression and NFI temporal occupancy of late target genes and enhanced Map2(+) neurite outgrowth. ETV1 also activated expression and NFI occupancy of the Etv1 gene itself, and this autoregulatory loop preceded ETV1 binding and activation of other coregulated target genes in vivo. These findings suggest a potential model in which ETV1 activates NFI temporal binding to a subset of late-expressed genes in a stepwise manner by initial positive feedback regulation of the Etv1 gene itself followed by activation of downstream coregulated targets as ETV1 expression increases. Sequential transcription factor autoregulation and subsequent binding to downstream promoters may provide an intrinsic developmental timer for dendrite/synapse gene expression.

scholarly journals Feedback Regulation of PRL Secretion Is Mediated by the Transcription Factor, Signal Transducer, and Activator of Transcription 5b

Endocrinology ◽  
2001 ◽  
Vol 142 (9) ◽  
pp. 3935-3940 ◽  
Author(s):  
David R. Grattan ◽  
Junjie Xu ◽  
Michael J. McLachlan ◽  
Ilona C. Kokay ◽  
Stephen J. Bunn ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Feedback Regulation ◽  
Signal Transducer

scholarly journals Multiple transcription-factor genes are early targets of phytochrome A signaling

2001 ◽  
Vol 98 (16) ◽  
pp. 9437-9442 ◽  
Author(s):  
J. M. Tepperman ◽  
T. Zhu ◽  
H.-S. Chang ◽  
X. Wang ◽  
P. H. Quail
Keyword(s):  
Transcription Factor ◽  
Phytochrome A ◽  
Transcription Factor Genes ◽  
Multiple Transcription Factor

scholarly journals Understanding the Shade Tolerance Responses Through Hints From Phytochrome A-Mediated Negative Feedback Regulation in Shade Avoiding Plants

2021 ◽  
Vol 12 ◽  
Author(s):  
Huiying Xu ◽  
Peirui Chen ◽  
Yi Tao
Keyword(s):  
Negative Feedback ◽  
Shade Tolerance ◽  
Dynamic Properties ◽  
Survival Rates ◽  
Feedback Regulation ◽  
Shade Avoidance ◽  
Phytochrome A ◽  
Negative Feedback Regulation ◽  
Signaling Components

Based on how plants respond to shade, we typically classify them into two groups: shade avoiding and shade tolerance plants. Under vegetative shade, the shade avoiding species induce a series of shade avoidance responses (SARs) to outgrow their competitors, while the shade tolerance species induce shade tolerance responses (STRs) to increase their survival rates under dense canopy. The molecular mechanism underlying the SARs has been extensively studied using the shade avoiding model plant Arabidopsis thaliana, while little is known about STRs. In Aarabidopsis, there is a PHYA-mediated negative feedback regulation that suppresses exaggerated SARs. Recent studies revealed that in shade tolerance Cardamine hirsuta plants, a hyperactive PHYA was responsible for suppressing shade-induced elongation growth. We propose that similar signaling components may be used by shade avoiding and shade tolerance plants, and different phenotypic outputs may result from differential regulation or altered dynamic properties of these signaling components. In this review, we summarized the role of PHYA and its downstream components in shade responses, which may provide insights into understanding how both types of plants respond to shade.

scholarly journals Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast

2014 ◽  
Vol 42 (15) ◽  
pp. 9573-9587 ◽  
Author(s):  
Eugenia Cisneros-Barroso ◽  
Tula Yance-Chávez ◽  
Ayako Kito ◽  
Reiko Sugiura ◽  
Alba Gómez-Hierro ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Transcription Factor ◽  
Nuclear Export ◽  
Mammalian Cells ◽  
Calcium Signalling ◽  
Feedback Regulation ◽  
Negative Feedback Regulation ◽  
Cycle Arrest ◽  
Cell Cycle Inhibition ◽  
Active Transcription

Abstract Calcium signals trigger the translocation of the Prz1 transcription factor from the cytoplasm to the nucleus. The process is regulated by the calcium-activated phosphatase calcineurin, which activates Prz1 thereby maintaining active transcription during calcium signalling. When calcium signalling ceases, Prz1 is inactivated by phosphorylation and exported to the cytoplasm. In budding yeast and mammalian cells, different kinases have been reported to counter calcineurin activity and regulate nuclear export. Here, we show that the Ca2+/calmodulin-dependent kinase Cmk1 is first phosphorylated and activated by the newly identified kinase CaMKK2 homologue, Ckk2, in response to Ca2+. Then, active Cmk1 binds, phosphorylates and inactivates Prz1 transcription activity whilst at the same time cmk1 expression is enhanced by Prz1 in response to Ca2+. Furthermore, Cdc25 phosphatase is also phosphorylated by Cmk1, inducing cell cycle arrest in response to an increase in Ca2+. Moreover, cmk1 deletion shows a high tolerance to chronic exposure to Ca2+, due to the lack of cell cycle inhibition and elevated Prz1 activity. This work reveals that Cmk1 kinase activated by the newly identified Ckk2 counteracts calcineurin function by negatively regulating Prz1 activity which in turn is involved in activating cmk1 gene transcription. These results are the first insights into Cmk1 and Ckk2 function in Schizosaccharomyces pombe.

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