scholarly journals Nucleotide Sequences of cDNAs Encoding Two Members of the Brazil Nut Methionine-Rich 2S Albumin Gene Family

1992 ◽  
Vol 98 (4) ◽  
pp. 1520-1522 ◽  
Author(s):  
Susan B. Altenbach ◽  
Karen W. Pearson ◽  
Samuel S. M. Sun
1995 ◽  
Vol 1 (3) ◽  
pp. 295-301 ◽  
Author(s):  
Thomas Pickardt ◽  
Isolde Saalbach ◽  
David Waddell ◽  
Martin Meixner ◽  
Klaus Müntz ◽  
...  

1987 ◽  
Vol 7 (5) ◽  
pp. 1938-1946
Author(s):  
K Shahan ◽  
M Gilmartin ◽  
E Derman

The mouse major urinary proteins (MUPs) are encoded by a gene family of about 35 to 40 members. MUPs are synthesized in at least six secretory tissues under a variety of developmental and endocrine controls, but the identities of the individual genes expressed in each tissue have not previously been established. In this article, we present the nucleotide sequences of five MUP mRNAs which we designate MUP I through V. MUPs I, II, and III are the most abundant MUP mRNA species in the liver, and MUPs IV and V are the most abundant MUP mRNA species in the lachrymal gland and the submaxillary gland, respectively. The sequence data show that each of the five mRNAs is encoded by a distinct member of the gene family. The structures of the MUP mRNA consist of interspersed segments of variable and conserved sequences. On the basis of the sequences of the variable segments, gene-specific panels of synthetic oligonucleotide probes were prepared. The gene-specific panels were used to identify cloned genes and, as described in the accompanying paper (K. Shahan, M. Denaro, M. Gilmartin, Y. Shi, and E. Derman, Mol. Cell. Biol. 7:1947-1954, 1987), to characterize the expression of MUP genes I through V.


1999 ◽  
Vol 380 (12) ◽  
pp. 1431-1434 ◽  
Author(s):  
Hitomi Nishio ◽  
Hamdi K. Hamdi ◽  
Achilles Dugaiczyk

Abstract The albumin gene family arose in a series of duplication events which gave rise to symmetry in its structure. The four genes are tandemly linked on human chromosome 4q in the order: 5′ ALB-5′ AFP-5′ ALF-5′ DBP-centromere, and their introns display a symmetrical and repetitive pattern that is shared by members of the gene family. These repetitive motifs provide an internal reference, allowing observations of evolutionary changes within a single line (human) of evolutionary descent. The four genes and three intergenic regions between them increase in size as they get closer to the centromere. An invasion by multiple repetitive DNA elements may account, in part, for this expansion.


Gene ◽  
1991 ◽  
Vol 108 (2) ◽  
pp. 311-312 ◽  
Author(s):  
T. Nakayama ◽  
S. Takechi ◽  
T. Ohshige ◽  
K. Kondo ◽  
K. Yamamoto

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Anatoliy T. Ivashchenko ◽  
Assel S. Issabekova ◽  
Olga A. Berillo

OnlyPTPN12, MSH6, andZEB1have significant miR-1279 binding sites among paralogous genes of human tyrosine phosphatase family, DNA mismatch repair family, and zinc finger family, respectively. All miRNA binding sites are located within CDSs of studied mRNAs. Nucleotide sequences of hsa-miR-1279 binding sites with mRNAs of humanPTPN12, MSH6, andZEB1genes encode TKEQYE, EGSSDE, and GEKPYE oligopeptides, respectively. The conservation of miRNA binding sites encoding oligopeptides has been revealed. MRNAs of many paralogs of zinc finger gene family have from 1 to 12 binding sites coding the same GEKPYE hexapeptide. MRNAs ofPTPN12, MSH6, andZEB1orthologous genes from different animal species have binding sites for hsa-miR-1279 which consist of homologous oligonucleotides encoding similar human oligopeptides TKEQYE, EGSSDE, and GEKPYE. MiR-548j, miR-548m, and miR-548d-5p have homologous binding sites in the mRNA ofPTPN12orthologous genes which encode PRTRSC, TEATDI, and STASAT oligopeptides, respectively. All regions of miRNA are important for binding with the mRNA.


FEBS Journal ◽  
2004 ◽  
Vol 272 (2) ◽  
pp. 341-352 ◽  
Author(s):  
F. Javier Moreno ◽  
Fred A. Mellon ◽  
Martin S. J. Wickham ◽  
Andrew R. Bottrill ◽  
E. N. Clare Mills

2005 ◽  
Vol 53 (1) ◽  
pp. 123-131 ◽  
Author(s):  
Stef J. Koppelman ◽  
Willem F. Nieuwenhuizen ◽  
Marco Gaspari ◽  
Leon M. J. Knippels ◽  
André H. Penninks ◽  
...  
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