scholarly journals Cytochrome and Alternative Pathway Respiration during Transient Ammonium Assimilation by N-Limited Chlamydomonas reinhardtii

1990 ◽  
Vol 94 (3) ◽  
pp. 1131-1136 ◽  
Author(s):  
Harold G. Weger ◽  
Antony R. Chadderton ◽  
Min Lin ◽  
Robert D. Guy ◽  
David H. Turpin
Keyword(s):  
Chlamydomonas Reinhardtii ◽  
Alternative Pathway ◽  
Ammonium Assimilation

Nitric oxide controls nitrate and ammonium assimilation in Chlamydomonas reinhardtii

2013 ◽  
Vol 64 (11) ◽  
pp. 3373-3383 ◽  
Author(s):  
Emanuel Sanz-Luque ◽  
Francisco Ocaña-Calahorro ◽  
Angel Llamas ◽  
Aurora Galvan ◽  
Emilio Fernandez
Keyword(s):  
Nitric Oxide ◽  
Chlamydomonas Reinhardtii ◽  
Ammonium Assimilation ◽  
Nitrate And Ammonium Assimilation

Proteolytic processing of the amyloid-beta protein precursor of Alzheimer's disease

2002 ◽  
Vol 38 ◽  
pp. 37-49 ◽  
Author(s):  
Janelle Nunan ◽  
David H Small
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Beta ◽  
Alternative Pathway ◽  
Protein A ◽  
Proteolytic Processing ◽  
Gamma Secretase ◽  
Amyloid Beta Protein ◽  
Protein Precursor ◽  
Amyloid Beta Protein Precursor

The proteolytic processing of the amyloid-beta protein precursor plays a key role in the development of Alzheimer's disease. Cleavage of the amyloid-beta protein precursor may occur via two pathways, both of which involve the action of proteases called secretases. One pathway, involving beta- and gamma-secretase, liberates amyloid-beta protein, a protein associated with the neurodegeneration seen in Alzheimer's disease. The alternative pathway, involving alpha-secretase, precludes amyloid-beta protein formation. In this review, we describe the progress that has been made in identifying the secretases and their potential as therapeutic targets in the treatment or prevention of Alzheimer's disease.

Sign in / Sign up

Export Citation Format

Share Document