scholarly journals A Guanine Nucleotide Exchange Factor for Rab5 Proteins Is Essential for Intracellular Transport of the Proglutelin from the Golgi Apparatus to the Protein Storage Vacuole in Rice Endosperm

2013 ◽  
Vol 162 (2) ◽  
pp. 663-674 ◽  
Author(s):  
Masako Fukuda ◽  
Liuying Wen ◽  
Mio Satoh-Cruz ◽  
Yasushi Kawagoe ◽  
Yoshiaki Nagamura ◽  
...  
Viruses ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 682
Author(s):  
José L. Martínez ◽  
Carlos F. Arias

The guanine nucleotide exchange factor GBF1 is a well-known factor that can activate different ADP-ribosylation factor (Arf) proteins during the regulation of different cellular vesicular transport processes. In the last decade, it has become increasingly evident that GBF1 can also regulate different steps of the replication cycle of RNA viruses belonging to different virus families. GBF1 has been shown not only to facilitate the intracellular traffic of different viral and cellular elements during infection, but also to modulate the replication of viral RNA, the formation and maturation of viral replication complexes, and the processing of viral proteins through mechanisms that do not depend on its canonical role in intracellular transport. Here, we review the various roles that GBF1 plays during the replication of different RNA viruses.


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