scholarly journals Perturbations of Amino Acid Metabolism Associated with Glyphosate-Dependent Inhibition of Shikimic Acid Metabolism Affect Cellular Redox Homeostasis and Alter the Abundance of Proteins Involved in Photosynthesis and Photorespiration

2011 ◽  
Vol 157 (1) ◽  
pp. 256-268 ◽  
Author(s):  
Pedro Diaz Vivancos ◽  
Simon P. Driscoll ◽  
Christopher A. Bulman ◽  
Liu Ying ◽  
Kaveh Emami ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Shikimic Acid ◽  
Redox Homeostasis ◽  
Cellular Redox ◽  
Dependent Inhibition

scholarly journals Amino Acid Metabolism in Cancer Drug Resistance

Cells ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 140
Author(s):  
Hee-Chan Yoo ◽  
Jung-Min Han
Keyword(s):  
Drug Resistance ◽  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Epigenetic Modification ◽  
Redox Homeostasis ◽  
Resistance Mechanisms ◽  
Cancer Drug ◽  
Cancer Therapies

Despite the numerous investigations on resistance mechanisms, drug resistance in cancer therapies still limits favorable outcomes in cancer patients. The complexities of the inherent characteristics of tumors, such as tumor heterogeneity and the complicated interaction within the tumor microenvironment, still hinder efforts to overcome drug resistance in cancer cells, requiring innovative approaches. In this review, we describe recent studies offering evidence for the essential roles of amino acid metabolism in driving drug resistance in cancer cells. Amino acids support cancer cells in counteracting therapies by maintaining redox homeostasis, sustaining biosynthetic processes, regulating epigenetic modification, and providing metabolic intermediates for energy generation. In addition, amino acid metabolism impacts anticancer immune responses, creating an immunosuppressive or immunoeffective microenvironment. A comprehensive understanding of amino acid metabolism as it relates to therapeutic resistance mechanisms will improve anticancer therapeutic strategies.

Amino Acid Metabolism

1979 ◽  
Vol 7 (1) ◽  
pp. 261-262
Author(s):  
E. V. ROWSELL
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Effect of intravenous bicarbonate administration on postoperative amino acid metabolism

1985 ◽  
Vol 4 ◽  
pp. 141-146 ◽  
Author(s):  
K VESTERBERG ◽  
J BERGSTROM ◽  
P FURST ◽  
U LEANDER ◽  
E VINNARS
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Different sensitivity of glucose and amino acid metabolism to insulin in NIDDM

Diabetes ◽  
1993 ◽  
Vol 42 (12) ◽  
pp. 1868-1877 ◽  
Author(s):  
L. Luzi ◽  
A. S. Petrides ◽  
R. A. De Fronzo
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism
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