scholarly journals End-Product Control of Carbon Metabolism in Culture-Grown Sugar Beet Plants (Molecular and Physiological Evidence on Accelerated Leaf Development and Enhanced Gene Expression)

1995 ◽  
Vol 108 (4) ◽  
pp. 1647-1656 ◽  
Author(s):  
Y. Kovtun ◽  
J. Daie
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Russell R. Fling ◽  
Claire M. Doskey ◽  
Kelly A. Fader ◽  
Rance Nault ◽  
Tim R. Zacharewski

Abstract 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a persistent environmental contaminant, induces steatosis that can progress to steatohepatitis with fibrosis, pathologies that parallel stages in the development of non-alcoholic fatty liver disease (NAFLD). Coincidently, one carbon metabolism (OCM) gene expression and metabolites are often altered during NAFLD progression. In this study, the time- and dose-dependent effects of TCDD were examined on hepatic OCM in mice. Despite AhR ChIP-seq enrichment at 2 h, OCM gene expression was not changed within 72 h following a bolus dose of TCDD. Dose-dependent repression of methionine adenosyltransferase 1A (Mat1a), adenosylhomocysteinase (Achy) and betaine-homocysteine S-methyltransferase (Bhmt) mRNA and protein levels following repeated treatments were greater at 28 days compared to 8 days. Accordingly, levels of methionine, betaine, and homocysteic acid were dose-dependently increased, while S-adenosylmethionine, S-adenosylhomocysteine, and cystathionine exhibited non-monotonic dose-dependent responses consistent with regulation by OCM intermediates and repression of glycine N-methyltransferase (Gnmt). However, the dose-dependent effects on SAM-dependent metabolism of polyamines and creatine could not be directly attributed to alterations in SAM levels. Collectively, these results demonstrate persistent AhR activation disrupts hepatic OCM metabolism at the transcript, protein and metabolite levels within context of TCDD-elicited progression of steatosis to steatohepatitis with fibrosis.


2009 ◽  
Vol 58 (3) ◽  
pp. 235-241 ◽  
Author(s):  
Yun-Hee Kim ◽  
Cha Young Kim ◽  
Haeng-Soon Lee ◽  
Sang-Soo Kwak

1961 ◽  
Vol 56 (3) ◽  
pp. 417-429 ◽  
Author(s):  
John L. Hammerton

Seedling beet plants grown on a fine soil separate produced more and larger leaves than those grown on coarser separates. This result has been ascribed to the greater quantity of available water, and the better root-soil water contact, in the fine separate compared with the others. Difficulties of root establishment in the coarser separates may retard the start of leaf development relative to that in the fine separates. Soil separates also affected leaf number, in some experiments, through their effect on seedling emergence, in that rapid emergence gave seedlings a slightly longer period for leaf production.Fodder beet plants (variety Red Otofte) had a greater leaf number per plant at all counts than plants of any of the sugar-beet strains grown. Polyploid sugar-beet seedlings had larger leaves than diploid seedling.Nitrogen applications to the seed-bed did not stimulate leaf production. In one instance, heavy fertilizerdressingsretardedleafproduction,probably by an osmotic effect.


2009 ◽  
Vol 36 (5) ◽  
pp. 277-282 ◽  
Author(s):  
Yin Leng Lee ◽  
Xinran Xu ◽  
Sylvan Wallenstein ◽  
Jia Chen

2006 ◽  
Vol 75 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Yasufumi Suzue ◽  
Miwa Tsukuda ◽  
Saori Hatano ◽  
Yoshinori Kanayama ◽  
Kunio Yamada ◽  
...  

2011 ◽  
Vol 4 (1) ◽  
pp. 127-143 ◽  
Author(s):  
Maria V. Busi ◽  
Maria E. Gomez-Lobato ◽  
Sebastian P. Rius ◽  
Valeria R. Turowski ◽  
Paula Casati ◽  
...  

PLoS Genetics ◽  
2013 ◽  
Vol 9 (7) ◽  
pp. e1003655 ◽  
Author(s):  
Toshiaki Tameshige ◽  
Hironori Fujita ◽  
Keiro Watanabe ◽  
Koichi Toyokura ◽  
Maki Kondo ◽  
...  

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