scholarly journals Slippery flows of a Carbopol gel in a microchannel

2020 ◽  
Vol 5 (8) ◽  
Author(s):  
Eliane Younes ◽  
Volfango Bertola ◽  
Cathy Castelain ◽  
Teodor Burghelea
Keyword(s):  
Carbopol Gel

Formulation and Evaluation of Carbopol Gel Containing Liposomes of Ketoconazole. (Part-II)

2009 ◽  
Vol 1 (2) ◽  
Author(s):  
Rakesh Patel ◽  
Hardik Patel ◽  
Ashok Baria
Keyword(s):  
Antifungal Activity ◽  
Rat Skin ◽  
Albino Rat ◽  
In Vitro Drug Release ◽  
Carbopol Gel ◽  
Liposomal Formulations ◽  
Release Drug ◽  
In Vitro Permeation ◽  
In Vitro Antifungal Activity

The aim of this work was to prepare and evaluate the topical carbopol gel formulation containing ketoconazole encapsulated liposomes. Ketoconazole loaded liposomes were prepared by thin film hydration technique. The prepared liposomes were incorporated into 1% carbopol gel, and the systems were evaluated for in-vitro drug release, drug retention into skin and in-vitro antifungal activity. The in-vitro permeation of ketoconazole using wistar albino rat skin from liposomal gel was compared with that of plain drug gel and also with plain drug cream containing 2% w/w of ketoconazole. The release of ketoconazole from liposomal gel was much slower than from non liposomal formulations. Gel containing liposomal ketoconazole showed maximum antifungal activity after 30 hours over plain ketoconazole gel and cream formulations.

scholarly journals Collagen Hydrolysate Prepared from Chicken By-Product as a Functional Polymer in Cosmetic Formulation

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 2021
Author(s):  
Aneta Prokopová ◽  
Jana Pavlačková ◽  
Pavel Mokrejš ◽  
Robert Gál
Keyword(s):  
Water Loss ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Skin Elasticity ◽  
Cosmetic Products ◽  
Collagen Hydrolysate ◽  
Carbopol Gel ◽  
Cosmetic Formulation ◽  
The Right ◽  
Positive Effect

Chicken stomachs can be processed into collagen hydrolysate usable in cosmetic products. The aim of the study was to verify the effects of a carbopol gel formulation enriched with 1.0% (w/w) chicken hydrolysate on the properties of the skin in the periorbital area after regular application twice a day for eight weeks in volunteers ageed 50 ± 9 years. Skin hydration, transepidermal water loss (TEWL), skin elasticity and skin relief were evaluated. Overall, skin hydration increased by 11.82% and 9.45%, TEWL decreased by 25.70% and 17.80% (always reported for the right and left area). Generally, there was an increase in skin elasticity, a decrease in skin roughness, as the resonance times decreased by 85%. The average reduction of wrinkles was 35.40% on the right and 41.20% on the left. For all results, it can be seen that the longer the cosmetic gel formulation is applied, the better the results. Due to the positive effect on the quality and functionality of the skin, it is possible to apply the cosmetic gel formulation in the periorbital area. The advantage of the product with chicken collagen hydrolysate is also the biocompatibility with the skin and the biodegradability of the formulation.

scholarly journals Investigating the Wound Healing Potential of the Polyherbal Gels Prepared with Ficus Extract

2018 ◽  
Vol 8 (2) ◽  
pp. 13-16
Author(s):  
Mahender K ◽  
Ravi D ◽  
Chaitanya Kumar K ◽  
Mothilal K
Keyword(s):  
Wound Healing ◽  
Inflammatory Response ◽  
Human Body ◽  
Healing Process ◽  
The Body ◽  
Wound Healing Process ◽  
Aqueous Extracts ◽  
Standard Drug ◽  
Carbopol Gel ◽  
Ficus Benghalensis

Wounds are nothing but any damage to the tissue or skin that can be healed. The wound healing process is usually built in the human body to self heal many wounds. When there is an injury in the body, there is an inflammatory response that is generated in the body, and the cells begin to raise the collagen levels in the skin which enables to increase the healing process. Ficus species of plants are famous for their potency to treat diseases in various Indian systems of medicine and the tree is commonly called as a banyan. Especially the plant in the species benghalensis is used to treat rheumatism, wounds and other skin related problems like an ulcer. The herbal gels were prepared using the incorporation of the aqueous extracts of the plant Ficus benghalensis into carbopol gel. They were investigated for the wound healing potential compared to the betadine drug standard. The gels at a concentration 200mg/g of the gel showed better activity compared to the gel at 100mg/g and the standard drug, betadine.

Phytotoxicity, Poison Retention, Palatability, and Acceptance of Carriers Used in Compound-1080-Foliage Baits for Control of Feral Goats.

1991 ◽  
Vol 18 (6) ◽  
pp. 687 ◽  
Author(s):  
JP Parkes
Keyword(s):  
New Zealand ◽  
Plant Species ◽  
Food Plants ◽  
Carbopol Gel ◽  
Long Life

Feral goats have been controlled in New Zealand by treating leaves of favoured food plants with the poison sodium monofluoroacetate (compound 1080) in a suitable carrier, either carbopol gel or petrolatum grease. The effect of these 2 carriers on the most suitable plant species (mahoe), their retention of 1080, their comparative palatability to goats, and the acceptance of the least palatable, petrolatum, were studied in a series of trials. Both carriers caused baited leaves to absciss, and the rate of abscission increased when 1080 was included. Toxic petrolatum was 3 times less phytotoxic than carbopol and retained 1080 for much longer (carbopol lost most of its toxin after 200 mm of rain). Abscissed petrolatum-treated leaves retained much of their toxicity for at least a year. Goats detected and, to some extent, rejected leaves of all treatments, either by not eating them or by spitting them out (particularly petrolatum-treated leaves). However, use of iophenoxic acid as a bait marker indicated that even petrolatum-treated leaves were consumed by 24 of 30 goats tested. Carbopol with 1080 is recommended for use where its distribution is sufficient to place all goats at immediate risk. Petrolatum is not recommended for general use, although it can be used in areas where a long-life bait is needed.

Antimicrobial action of photodynamic therapy in root canals using LED curing light, curcumin and carbopol gel

2019 ◽  
Vol 52 (7) ◽  
pp. 1010-1019 ◽  
Author(s):  
D. F. Oda ◽  
M. A. H. Duarte ◽  
F. B. Andrade ◽  
L. T. Moriyama ◽  
V. S. Bagnato ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Antimicrobial Action ◽  
Root Canals ◽  
Carbopol Gel ◽  
Curing Light

Enhancement of the intranasal delivery of insulin via a novel mucoadhesive Carbopol gel

2010 ◽  
Vol 62 (7) ◽  
pp. 866-872 ◽  
Author(s):  
Walaa Ahmed El-Dakrouri ◽  
Howida Kamal Ibrahim ◽  
Mohamed Khaled Ghorab ◽  
Mahmoud Mohamed Ghorab
Keyword(s):  
Intranasal Delivery ◽  
Carbopol Gel

scholarly journals Pouteria ramiflora leaf extract on emulgel in wound healing activity in diabetic rats

2022 ◽  
Vol 82 ◽  
Author(s):  
A. C. L. Corrêa ◽  
A. K. M. Oliveira ◽  
D. M. Dourado ◽  
G. G. Facco ◽  
L. M. A. Bento ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Ethanolic Extract ◽  
Inflammatory Cells ◽  
Diabetic Rats ◽  
Carbopol Gel ◽  
Post Operative Period ◽  
Healing Of Skin Wounds ◽  
Histopathological Results ◽  
And Control ◽  
Wound Healing Activity

Abstract The genus Pouteria has been studied because it presents various activities, among which is its anti-inflammatory potential. The effects of Pouteria ramiflora Carbopol gel on the healing of skin wounds in diabetic rats were evaluated by microscopic imaging. Streptozotocin was administered intraperitoneally in animals that had fasted for 12 hours, a situation confirmed by the glycemic index (˃ 240 mg dL-1). An excision on the back of the animals was performed and three groups were formed: Control (Gel), Ethanolic extract (Ext) and Gel + extract 2% (Ext+gel); the histopathological evaluation occurred on the 7th, 14th, 21st and 30th days after the post-operative period. The results of the phytochemical prospecting of P. ramiflora extract demonstrated the major presence of phenolic compounds and flavonoids; the assessment of the inflammatory infiltrate on the 7th day was higher on group Ext and Ext+gel when compared to group Control; on the 14th day control and Ext (p<0.05). The quantification of fibroblasts was higher on the 7th day among the three treatments, control and Ext (p<0.05), on the 21st day. Angiogenesis showed a higher number of vessels in Ext+gel group (p<0.05) on the 7th day; in Control, Ext and Ext+gel (p<0.05) on the 14th day; and Control and Ext (p<0.05)on the 21st day. The histopathological results showed that the formulation Ext+gel was efficient in tissue reparation and decrease in inflammatory cells on the diabetic’s animals.

Control of Bennett's and Tammar Wallabies in New Zealand Using Compound 1080 Gel on Foliage Baits.

1990 ◽  
Vol 17 (5) ◽  
pp. 541 ◽  
Author(s):  
B Warburton
Keyword(s):  
New Zealand ◽  
Carbopol Gel ◽  
Indigenous Forest

Trials were carried out against Bennett's wallabies (Macropus rufogriseus rufogriseus) and tammar wallabies (M. eugenii) in areas of indigenous forest where browsing is preventing or damaging regeneration. Compound 1080 (sodium monofluoroacetate) in a carbopol gel was spread on the foliage of palatable plants. Numbers of Bennett's wallabies were reduced by 91% and tammar wallabies by 87%. These kill estimates compare favourably with those achieved using aerially sown baits. The costs per hectare of gel poisoning were estimated to be as little as 40% of those for aerial baiting, but the costs of using gel will increase as the control areas become larger, more rugged, and less easily traversed on foot.

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