scholarly journals Pseudoconformal universe: Late-time contraction and generation of tensor modes

2013 ◽  
Vol 87 (4) ◽  
Author(s):  
S. Mironov
Keyword(s):  
Late Time ◽  
Time Contraction

scholarly journals Unitarity at the late time boundary of de Sitter

2020 ◽  
Vol 2020 (6) ◽  
Author(s):  
Gizem Şengör ◽  
Constantinos Skordis
Keyword(s):  
Late Time ◽  
De Sitter ◽  
Time Boundary

scholarly journals DARK ENERGY, WITH SIGNATURES

2010 ◽  
Vol 19 (14) ◽  
pp. 2325-2330
Author(s):  
SOURISH DUTTA ◽  
ROBERT J. SCHERRER ◽  
STEPHEN D. H. HSU
Keyword(s):  
Dark Energy ◽  
Equation Of State ◽  
Energy Scale ◽  
Fine Tuning ◽  
Time Dependent ◽  
Late Time ◽  
Particle Content ◽  
Energy Field ◽  
Energy Models ◽  
New Energy

We propose a class of simple dark energy models which predict a late-time dark radiation component and a distinctive time-dependent equation of state w(z) for redshift z < 3. The dark energy field can be coupled strongly enough to standard model particles to be detected in colliders, and the model requires only modest additional particle content and little or no fine-tuning other than a new energy scale of order milli-electron volts.

scholarly journals Observations of Hawking radiation: the Page curve and baby universes

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Donald Marolf ◽  
Henry Maxfield
Keyword(s):  
Black Holes ◽  
Quantum Systems ◽  
Late Time ◽  
Asymptotically Flat ◽  
Black Hole Information ◽  
Flat Spacetimes ◽  
The Cost ◽  
Baby Universes ◽  
Time Extrapolation ◽  
Asymptotic Observers

AbstractWe reformulate recent insights into black hole information in a manner emphasizing operationally-defined notions of entropy, Lorentz-signature descriptions, and asymptotically flat spacetimes. With the help of replica wormholes, we find that experiments of asymptotic observers are consistent with black holes as unitary quantum systems, with density of states given by the Bekenstein-Hawking formula. However, this comes at the cost of superselection sectors associated with the state of baby universes. Spacetimes studied by Polchinski and Strominger in 1994 provide a simple illustration of the associated concepts and techniques, and we argue them to be a natural late-time extrapolation of replica wormholes. The work aims to be self-contained and, in particular, to be accessible to readers who have not yet mastered earlier formulations of the ideas above.

scholarly journals Late Time Attractors of Some Varying Chaplygin Gas Cosmological Models

Symmetry ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 769
Author(s):  
Martiros Khurshudyan ◽  
Ratbay Myrzakulov
Keyword(s):  
Dark Energy ◽  
Gravitational Interaction ◽  
Chaplygin Gas ◽  
Cosmological Models ◽  
Late Time ◽  
Time Behavior ◽  
Coincidence Problem ◽  
Energy Models ◽  
Non Linear ◽  
Bayesian Machine Learning

The goal of this paper is to study new cosmological models where the dark energy is a varying Chaplygin gas. This specific dark energy model with non-linear EoS had been often discussed in modern cosmology. Contrary to previous studies, we consider new forms of non-linear non-gravitational interaction between dark matter and assumed dark energy models. We applied the phase space analysis allowing understanding the late time behavior of the models. It allows demonstrating that considered non-gravitational interactions can solve the cosmological coincidence problem. On the other hand, we applied Bayesian Machine Learning technique to learn the constraints on the free parameters. In this way, we gained a better understanding of the models providing a hint which of them can be ruled out. Moreover, the learning based on the simulated expansion rate data shows that the models cannot solve the H0 tension problem.

ICAM-1-independent adhesion of neutrophils to phorbol ester-stimulated human airway epithelial cells

1999 ◽  
Vol 277 (3) ◽  
pp. L465-L471 ◽  
Author(s):  
Alessandro Celi ◽  
Silvana Cianchetti ◽  
Stefano Petruzzelli ◽  
Stefano Carnevali ◽  
Filomena Baliva ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Airway Epithelial Cells ◽  
Bronchial Epithelial Cells ◽  
Neutrophil Adhesion ◽  
Late Time ◽  
Airway Epithelial ◽  
Bronchial Epithelial ◽  
Human Airway ◽  
Stimulation Of ◽  
Human Airway Epithelial Cells

Intercellular adhesion molecule-1 (ICAM-1) is the only inducible adhesion receptor for neutrophils identified in bronchial epithelial cells. We stimulated human airway epithelial cells with various agonists to evaluate whether ICAM-1-independent adhesion mechanisms could be elicited. Phorbol 12-myristate 13-acetate (PMA) stimulation of cells of the alveolar cell line A549 caused a rapid, significant increase in neutrophil adhesion from 11 ± 3 to 49 ± 7% (SE). A significant increase from 17 ± 4 to 39 ± 6% was also observed for neutrophil adhesion to PMA-stimulated human bronchial epithelial cells in primary culture. Although ICAM-1 expression was upregulated by PMA at late time points, it was not affected at 10 min when neutrophil adhesion was already clearly enhanced. Antibodies to ICAM-1 had no effect on neutrophil adhesion. In contrast, antibodies to the leukocyte integrin β-chain CD18 totally inhibited the adhesion of neutrophils to PMA-stimulated epithelial cells. These results demonstrate that PMA stimulation of human airway epithelial cells causes an increase in neutrophil adhesion that is not dependent on ICAM-1 upregulation.

scholarly journals Growth and structure of multiphase gas in the cloud-crushing problem with cooling

2020 ◽  
Vol 501 (1) ◽  
pp. 1143-1159
Author(s):  
Vijit Kanjilal ◽  
Alankar Dutta ◽  
Prateek Sharma
Keyword(s):  
Mixing Layer ◽  
Cooling Time ◽  
Radiative Cooling ◽  
Late Time ◽  
Dense Gas ◽  
Mixed Gas ◽  
Continuous Growth ◽  
Dense Cloud ◽  
Set Up ◽  
Background Gas

ABSTRACT We revisit the problem of the growth of dense/cold gas in the cloud-crushing set-up with radiative cooling. The relative motion between the dense cloud and the diffuse medium produces a turbulent boundary layer of mixed gas with a short cooling time. This mixed gas may explain the ubiquity of the range of absorption/emission lines observed in various sources such as the circumgalactic medium and galactic/stellar/active galactic nucleus outflows. Recently, Gronke & Oh showed that the efficient radiative cooling of the mixed gas can lead to continuous growth of the dense cloud. They presented a threshold cloud size for the growth of dense gas that was contradicted by the more recent works of Li et al. & Sparre et al. These thresholds are qualitatively different as the former is based on the cooling time of the mixed gas whereas the latter is based on the cooling time of the hot gas. Our simulations agree with the threshold based on the cooling time of the mixed gas. We argue that the radiative cloud-crushing simulations should be run long enough to allow for the late-time growth of the dense gas due to cooling of the mixed gas but not so long that the background gas cools catastrophically. Moreover, the simulation domain should be large enough that the mixed gas is not lost through the boundaries. While the mixing layer is roughly isobaric, the emissivity of the gas at different temperatures is fundamentally different from an isobaric single-phase steady cooling flow.

scholarly journals Nuclear burning in collapsar accretion discs

2020 ◽  
Vol 499 (3) ◽  
pp. 4097-4113 ◽  
Author(s):  
Yossef Zenati ◽  
Daniel M Siegel ◽  
Brian D Metzger ◽  
Hagai B Perets
Keyword(s):  
Angular Momentum ◽  
Gamma Ray ◽  
Nuclear Reactions ◽  
Reaction Network ◽  
Accretion Discs ◽  
Late Time ◽  
Rotating Stars ◽  
Stellar Envelope ◽  
Nuclear Burning ◽  
R Process

ABSTRACT The core collapse of massive, rapidly-rotating stars are thought to be the progenitors of long-duration gamma-ray bursts (GRB) and their associated hyperenergetic supernovae (SNe). At early times after the collapse, relatively low angular momentum material from the infalling stellar envelope will circularize into an accretion disc located just outside the black hole horizon, resulting in high accretion rates necessary to power a GRB jet. Temperatures in the disc mid-plane at these small radii are sufficiently high to dissociate nuclei, while outflows from the disc can be neutron-rich and may synthesize r-process nuclei. However, at later times, and for high progenitor angular momentum, the outer layers of the stellar envelope can circularize at larger radii ≳ 107 cm, where nuclear reactions can take place in the disc mid-plane (e.g. 4He + 16O → 20Ne + γ). Here we explore the effects of nuclear burning on collapsar accretion discs and their outflows by means of hydrodynamical α-viscosity torus simulations coupled to a 19-isotope nuclear reaction network, which are designed to mimic the late infall epochs in collapsar evolution when the viscous time of the torus has become comparable to the envelope fall-back time. Our results address several key questions, such as the conditions for quiescent burning and accretion versus detonation and the generation of 56Ni in disc outflows, which we show could contribute significantly to powering GRB SNe. Being located in the slowest, innermost layers of the ejecta, the latter could provide the radioactive heating source necessary to make the spectral signatures of r-process elements visible in late-time GRB-SNe spectra.

scholarly journals Exogenous Alginate Protects Staphylococcus aureus from Killing by Pseudomonas aeruginosa

2019 ◽  
Vol 202 (8) ◽  
Author(s):  
Courtney E. Price ◽  
Dustin G. Brown ◽  
Dominique H. Limoli ◽  
Vanessa V. Phelan ◽  
George A. O’Toole
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Physical Space ◽  
Late Time ◽  
Protective Effects ◽  
Content Type ◽  
Alginate Production ◽  
The Impact

ABSTRACT Cystic fibrosis (CF) patients chronically infected with both Pseudomonas aeruginosa and Staphylococcus aureus have worse health outcomes than patients who are monoinfected with either P. aeruginosa or S. aureus. We showed previously that mucoid strains of P. aeruginosa can coexist with S. aureus in vitro due to the transcriptional downregulation of several toxic exoproducts typically produced by P. aeruginosa, including siderophores, rhamnolipids, and HQNO (2-heptyl-4-hydroxyquinoline N-oxide). Here, we demonstrate that exogenous alginate protects S. aureus from P. aeruginosa in both planktonic and biofilm coculture models under a variety of nutritional conditions. S. aureus protection in the presence of exogenous alginate is due to the transcriptional downregulation of pvdA, a gene required for the production of the iron-scavenging siderophore pyoverdine as well as the downregulation of the PQS (Pseudomonas quinolone signal) (2-heptyl-3,4-dihydroxyquinoline) quorum sensing system. The impact of exogenous alginate is independent of endogenous alginate production. We further demonstrate that coculture of mucoid P. aeruginosa with nonmucoid P. aeruginosa strains can mitigate the killing of S. aureus by the nonmucoid strain of P. aeruginosa, indicating that the mechanism that we describe here may function in vivo in the context of mixed infections. Finally, we investigated a panel of mucoid clinical isolates that retain the ability to kill S. aureus at late time points and show that each strain has a unique expression profile, indicating that mucoid isolates can overcome the S. aureus-protective effects of mucoidy in a strain-specific manner. IMPORTANCE CF patients are chronically infected by polymicrobial communities. The two dominant bacterial pathogens that infect the lungs of CF patients are P. aeruginosa and S. aureus, with ∼30% of patients coinfected by both species. Such coinfected individuals have worse outcomes than monoinfected patients, and both species persist within the same physical space. A variety of host and environmental factors have been demonstrated to promote P. aeruginosa-S. aureus coexistence, despite evidence that P. aeruginosa kills S. aureus when these organisms are cocultured in vitro. Thus, a better understanding of P. aeruginosa-S. aureus interactions, particularly mechanisms by which these microorganisms are able to coexist in proximal physical space, will lead to better-informed treatments for chronic polymicrobial infections.

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