scholarly journals Quantitative determination of optical transmission through subwavelength slit arrays in Ag films: Role of surface wave interference and local coupling between adjacent slits

2008 ◽  
Vol 77 (11) ◽  
Author(s):  
D. Pacifici ◽  
H. J. Lezec ◽  
Harry A. Atwater ◽  
J. Weiner
2021 ◽  
Vol 20 (3) ◽  
pp. 62-71
Author(s):  
A. A. Komar ◽  
D. A. Skuratovskaia ◽  
M. A. Vulf ◽  
H. Q. Vu ◽  
A. Darinskas ◽  
...  

Background. The pathogenesis of nonalcoholic fatty liver disease (NAFLD), which develops in obesity and type 2 diabetes mellitus (T2DM), is associated with the effects of inflammatory factors on the liver parenchyma and liver mitochondrial dysfunction.Aim. To determine the role of sTNFSF14 in the regulation of liver mitochondrial biogenesis in obese patients with and without T2DM.Materials and methods. The study included 263 obese patients with and without T2DM and 42 apparently healthy donors. Quantitative determination of cytokines in the blood plasma was performed by fluorescence flow cytometry. The level of relative gene expression in the liver biopsy samples was investigated by real-time PCR. Semi-quantitative determination of proteins in the liver biopsy samples was studied by western blotting.Results. The study showed that the levels of sTNFSF14, interleukin (IL)-10, gp130 / sIL-6Rb, and sIL-6Ra in the blood plasma of the obese patients without T2DM significantly exceeded the similar values in the control patients and obese patients with T2DM. In the liver biopsy samples of the obese patients with T2DM and a body mass index (BMI) > 40 kg / m2, the expression level of the dynamin-1-like protein (DRP1 / DNM1L) gene was lower than in the control group, and the expression level of the mitofusin 2 (MFN2) gene tended to be higher. Compared with the control group, an increase in the expression level of the NADH-ubiquinone oxidoreductase chain 4 (MT-ND4) gene was recorded in the liver of all the obese patients. The patients with obesity showed a decrease in the amount of mitochondrial DNA (mtDNA) compared with the control group.Conclusion. Thus, sTNFSF14, interacting with IL-10 and gp130 / sIL-6Rb in the circulation, positively effects the liver in the obese patients without T2DM. A low level of sTNFSF14 in the blood plasma of the obese patients with T2DM results in decreased mitochondrial division and increased cellular respiration.


2009 ◽  
Vol 17 (3) ◽  
pp. 192-207 ◽  
Author(s):  
Alfredo Saad-Filho ◽  
Ben Fine

AbstractOur final instalment in the debate with Jim Kincaid argues that his value-analysis suffers from weaknesses associated with both Ricardian and Rubinesque (mis-)interpretations of Marx. These approaches are methodologically flawed, because value-theory does not draw upon externally imposed theories or standards of logic or evidence to check the conceptual or empirical validity of its approach to the understanding of capitalism. Rather, Marxian value-theory involves reconstructing in thought the class-based production-processes underpinning capitalism through to their more complex and concrete consequences in the broader economic and social structures, agencies and processes, through which they are formed, albeit with definite effects of their own. Examination of the methodological shortcomings in Kincaid's analysis is followed by specific rebuttals of his claims about the (qualitative and quantitative) determination of value and price, the circulation of capital, the role of competition, fixed capital, productive labour and the leverage of value-theory in informing empirical studies.


2019 ◽  
pp. 215-221 ◽  
Author(s):  
Maxim Bolotov ◽  
Tatiana Levanova ◽  
Lev Smirnov ◽  
Arkady Pikovsky

We study the problem of robustness of synchronous states to disorder in the chain of phase oscillators with local coupling. The study combines a numerical determination of the existence and stability of synchronous states with an analytical investigation of the role of the phase shift and the level of disorder in the natural frequencies in the destruction of synchrony. We show that the presence of the phase shift facilitates robustness of the synchronous regime, at least up to its certain threshold value.


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