Bacteriophage T4 DNA ligase buffer

2006 ◽  
Vol 2006 (1) ◽  
pp. pdb.rec8207
Keyword(s):  
Bacteriophage T4 ◽  
Dna Ligase ◽  
T4 Dna Ligase

scholarly journals Effects of DNA-binding drugs on T4 DNA ligase

1990 ◽  
Vol 266 (2) ◽  
pp. 379-384 ◽  
Author(s):  
A Montecucco ◽  
G Pedrali-Noy ◽  
S Spadari ◽  
M Lestingi ◽  
G Ciarrocchi
Keyword(s):  
Dna Binding ◽  
Bacteriophage T4 ◽  
Drug Binding ◽  
Dna Ligase ◽  
Enzyme Complex ◽  
T4 Dna Ligase ◽  
Substrate Interaction ◽  
Dna Nicking

A number of DNA intercalating and externally binding drugs have been found to inhibit nick sealing, cohesive and blunt end ligation, AMP-dependent DNA topoisomerization and EDTA-induced DNA nicking mediated by bacteriophage T4 DNA ligase. The inhibition seems to arise from drug-substrate interaction so that formation of active DNA-Mg2(+)-AMP-enzyme complex is impaired while assembled and active complexes are not disturbed by drug binding to the substrate.

scholarly journals In Vitro Ligation of Oligodeoxynucleotides Containing C8-Oxidized Purine Lesions Using Bacteriophage T4 DNA Ligase†

Biochemistry ◽  
2007 ◽  
Vol 46 (12) ◽  
pp. 3734-3744 ◽  
Author(s):  
Xiaobei Zhao ◽  
James G. Muller ◽  
Mohan Halasyam ◽  
Sheila S. David ◽  
Cynthia J. Burrows
Keyword(s):  
Bacteriophage T4 ◽  
Dna Ligase ◽  
T4 Dna Ligase

Specificity of the nick-closing activity of bacteriophage T4 DNA ligase

Gene ◽  
1989 ◽  
Vol 76 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Dan Y. Wu ◽  
R.Bruce Wallace
Keyword(s):  
Bacteriophage T4 ◽  
Dna Ligase ◽  
T4 Dna Ligase

scholarly journals T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction

2018 ◽  
Vol 46 (19) ◽  
pp. 10474-10488 ◽  
Author(s):  
Ke Shi ◽  
Thomas E Bohl ◽  
Jeonghyun Park ◽  
Andrew Zasada ◽  
Shray Malik ◽  
...  
Keyword(s):  
Dna Ligase ◽  
T4 Dna Ligase ◽  
Sliding Clamp ◽  
Unique Mode

scholarly journals Comprehensive Profiling of Four Base Overhang Ligation Fidelity by T4 DNA Ligase and Application to DNA Assembly

2018 ◽  
Vol 7 (11) ◽  
pp. 2665-2674 ◽  
Author(s):  
Vladimir Potapov ◽  
Jennifer L. Ong ◽  
Rebecca B. Kucera ◽  
Bradley W. Langhorst ◽  
Katharina Bilotti ◽  
...  
Keyword(s):  
Dna Ligase ◽  
Dna Assembly ◽  
T4 Dna Ligase
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