scholarly journals Repeatedly reactivated memories become more resistant to hippocampal damage

2011 ◽  
Vol 18 (3) ◽  
pp. 132-135 ◽  
Author(s):  
H. Lehmann ◽  
K. C. McNamara
Keyword(s):  
Hippocampal Damage ◽  
Reactivated Memories

A Behavioral Characterization of Mice with Hippocampal Damage

2003 ◽  
Author(s):  
Rebecca F. Foltz ◽  
Maria M. Versluis ◽  
Mark E. Bardgett
Keyword(s):  
Hippocampal Damage ◽  
Behavioral Characterization

Dendrobium officinalis Flower Improves Learning and Reduces Memory Impairment by Mediating Antioxidant Effect and Balancing the Release of Neurotransmitters in Senescent Rats

2020 ◽  
Vol 23 (5) ◽  
pp. 402-410 ◽  
Author(s):  
Lin-Zi Li ◽  
Shan-Shan Lei ◽  
Bo Li ◽  
Fu-Chen Zhou ◽  
Ye-Hui Chen ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Brain Aging ◽  
Morris Water Maze Test ◽  
Control Group ◽  
Histopathological Analysis ◽  
Hippocampal Damage ◽  
Common Belief ◽  
Mao B ◽  
Positive Effects ◽  
The Brain

Aim and Objective: The Dendrobium officinalis flower (DOF) is popular in China due to common belief in its anti-aging properties and positive effects on “nourish yin”. However, there have been relatively few confirmatory pharmacological experiments conducted to date. The aim of this work was to evaluate whether DOF has beneficial effects on learning and memory in senescent rats, and, if so, to determine its potential mechanism of effect. Materials and Methods: SD rats were administrated orally DOF at a dose of 1.38, or 0.46 g/kg once a day for 8 weeks. Two other groups included a healthy untreated control group and a senescent control group. During the 7th week, a Morris water maze test was performed to assess learning and memory. At the end of the experiment, serum and brain samples were collected to measure concentrations of antioxidant enzymes, including malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GSH-Px) in serum, and the neurotransmitters, including γ-aminobutyric acid (γ-GABA), Glutamic (Glu), and monoamine oxidase B (MAO-B) in the brain. Histopathology of the hippocampus was assessed using hematoxylin-eosin (H&E) staining. Results: The results suggested that treatment with DOF improved learning as measured by escape latency, total distance, and target quadrant time, and also increased levels of γ-GABA in the brain. In addition, DOF decreased the levels of MDA, Glu, and MAO-B, and improved SOD and GSHPx. Histopathological analysis showed that DOF also significantly reduced structural lesions and neurodegeneration in the hippocampus relative to untreated senescent rats. Conclusion: DOF alleviated brain aging and improved the spatial learning abilities in senescent rats, potentially by attenuating oxidative stress and thus reducing hippocampal damage and balancing the release of neurotransmitters.

scholarly journals MAP-2 as an early marker of hippocampal damage after perinatal asphyxia and neuroprotective properties of Palmitoylethanolamide.

2021 ◽  
Vol 27 (S1) ◽  
pp. 1138-1139
Author(s):  
Francisco Capani ◽  
Lucas Udovin ◽  
Tamara Kobiec ◽  
Camila Menendez ◽  
Toro-Urrego Nicolas ◽  
...  
Keyword(s):  
Perinatal Asphyxia ◽  
Hippocampal Damage ◽  
Early Marker

Nano-curcumin versus curcumin in amelioration of deltamethrin-induced hippocampal damage

2020 ◽  
Vol 154 (2) ◽  
pp. 157-175 ◽  
Author(s):  
Sherif Mohamed Zaki ◽  
Waleed Ahmed Abd Algaleel ◽  
Reda Abdelnasser Imam ◽  
Ghada F. Soliman ◽  
Fatma M. Ghoneim
Keyword(s):  
Hippocampal Damage

Neuropeptide Y and somatostatin participate differently in the seizure-generating mechanisms following trimethyltin-induced hippocampal damage

2002 ◽  
Vol 44 (3) ◽  
pp. 237-248 ◽  
Author(s):  
Nako Ishikura ◽  
Koichi Tsunashima ◽  
Kei-ichiro Watanabe ◽  
Tsutomu Nishimura ◽  
Yoshio Minabe ◽  
...  
Keyword(s):  
Neuropeptide Y ◽  
Hippocampal Damage

scholarly journals Estradiol protects against hippocampal damage and impairments in fear conditioning resulting from transient global ischemia in mice

2012 ◽  
Vol 1443 ◽  
pp. 64-74 ◽  
Author(s):  
Jennah L. Durham ◽  
Katherine A. Jordan ◽  
Marijke J. DeVos ◽  
Erika K. Williams ◽  
Noah J. Sandstrom
Keyword(s):  
Fear Conditioning ◽  
Global Ischemia ◽  
Hippocampal Damage ◽  
Transient Global Ischemia

Infusion of human embryonic kidney cell line conditioned medium reverses kainic acid induced hippocampal damage in mice

Cytotherapy ◽  
2014 ◽  
Vol 16 (12) ◽  
pp. 1760-1770 ◽  
Author(s):  
Anandh Dhanushkodi ◽  
Chaitra Venugopal ◽  
Pradeep Kumar K. Bevinahal ◽  
Kiranmai S. Rai ◽  
Raju R. Trichur ◽  
...  
Keyword(s):  
Cell Line ◽  
Conditioned Medium ◽  
Kainic Acid ◽  
Kidney Cell ◽  
Hippocampal Damage ◽  
Kidney Cell Line ◽  
Human Embryonic Kidney ◽  
Human Embryonic Kidney Cell
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