scholarly journals Genome DNA sequencing around the EF-1 alpha multigene locus of Arabidopsis thaliana indicates a high gene density and a shuffling of noncoding regions.

1997 ◽  
Vol 7 (3) ◽  
pp. 198-209 ◽  
Author(s):  
D Tremousaygue ◽  
C Bardet ◽  
P Dabos ◽  
F Regad ◽  
F Pelese ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Dna Sequencing ◽  
Gene Density ◽  
Noncoding Regions ◽  
High Gene ◽  
High Gene Density

scholarly journals MOLECULAR MAPPING OF A GENE CLUSTER FLANKING THE DROSOPHILA DOPA DECARBOXYLASE GENE

Genetics ◽  
1984 ◽  
Vol 106 (4) ◽  
pp. 679-694
Author(s):  
Denise Gilbert ◽  
Jay Hirsh ◽  
T R F Wright
Keyword(s):  
Gene Cluster ◽  
Molecular Mapping ◽  
Gene Density ◽  
Dopa Decarboxylase ◽  
Chromosomal Dna ◽  
Potential Significance ◽  
High Gene ◽  
Complementation Groups ◽  
High Gene Density

ABSTRACT Nine lethal complementation groups flanking the Drosophila Dopa decarboxylase (Ddc) gene, have been localized within 100 kb of cloned chromosomal DNA. Six of these complementation groups are within 23 kb of DNA, and all ten complementation groups, including Ddc, lie within 78-82 kb of DNA. The potential significance of this unusually high gene density is discussed.

Different chromosomal distribution patterns of radiation-induced interchange breakpoints in barley: First post-treatment mitosis versus viable offspring

Genome ◽  
2001 ◽  
Vol 44 (1) ◽  
pp. 128-132 ◽  
Author(s):  
G Künzel ◽  
K I Gecheff ◽  
I Schubert
Keyword(s):  
Distribution Patterns ◽  
Gene Density ◽  
Post Treatment ◽  
Recombination Rates ◽  
Chromosomal Distribution ◽  
Chromosome Breaks ◽  
Translocation Breakpoints ◽  
High Gene ◽  
Radiation Induced ◽  
High Gene Density

Translocation breakpoints (TBs) induced by ionizing radiation are nonrandomly distributed along barley chromosomes. When first post-treatment mitoses were evaluated, centromeres and the heterochromatin-containing proximal segments tended to be more than randomly involved, and terminal segments to be less than randomly involved in translocations. Contrary to this, small chromosomal regions in median and distal arm positions, characterized by high recombination rates and high gene density, were identified as preferred sites for the origination of viable translocations, probably due to deviations in chromatin organization. Apparently, the position of a TB has an influence on the rate of viability versus elimination of the carrier cells. Surprisingly, TBs within centromeres and heterochromatin-containing segments seem to be more harmful for survival than those induced in gene-rich regions.Key words: Hordeum vulgare, radiation-induced chromosome breaks, translocation lines, breakpoint distribution.

A 1.8-Mb YAC Contig in Xp11.23: Identification of CpG Islands and Physical Mapping of CA Repeats in a Region of High Gene Density

Genomics ◽  
1994 ◽  
Vol 21 (2) ◽  
pp. 337-343 ◽  
Author(s):  
Michael P. Coleman ◽  
Andrea H. Németh ◽  
Louise Campbell ◽  
Chandrajit P. Raut ◽  
Jean Weissenbach ◽  
...  
Keyword(s):  
Physical Mapping ◽  
Cpg Islands ◽  
Gene Density ◽  
High Gene ◽  
Yac Contig ◽  
High Gene Density

Characterization of the amphioxus presenilin gene in a high gene-density genomic region illustrates duplication during the vertebrate lineage

Gene ◽  
2001 ◽  
Vol 279 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Amalia Martı́nez-Mir ◽  
Cristian Cañestro ◽  
Roser Gonzàlez-Duarte ◽  
Ricard Albalat
Keyword(s):  
Genomic Region ◽  
Gene Density ◽  
Vertebrate Lineage ◽  
High Gene ◽  
High Gene Density

Does the High Gene Density in the Sponge NK Homeobox Gene Cluster Reflect Limited Regulatory Capacity?

2008 ◽  
Vol 214 (3) ◽  
pp. 205-217 ◽  
Author(s):  
Bryony Fahey ◽  
Claire Larroux ◽  
Ben J. Woodcroft ◽  
Bernard M. Degnan
Keyword(s):  
Gene Cluster ◽  
Homeobox Gene ◽  
Gene Density ◽  
High Gene ◽  
Regulatory Capacity ◽  
High Gene Density

scholarly journals High-Frequency Homologous Recombination Occurred Preferentially in Populus

2021 ◽  
Vol 12 ◽  
Author(s):  
Xining Geng ◽  
Yufei Xia ◽  
Hao Chen ◽  
Kang Du ◽  
Jun Yang ◽  
...  
Keyword(s):  
Homologous Recombination ◽  
Ssr Markers ◽  
High Frequency ◽  
Chromosome Doubling ◽  
Embryo Sac ◽  
Populus Tomentosa ◽  
Gene Density ◽  
High Gene ◽  
Postmeiotic Segregation ◽  
High Gene Density

Homologous recombination (HR), the most significant event in meiosis, has important implications for genetic diversity and evolution in organisms. Heteroduplex DNA (hDNA), the product of HR, can be captured by artificially induced chromosome doubling during the development of the embryo sac to inhibit postmeiotic segregation, subsequently, and hDNAs are directly detected using codominant simple sequence repeat (SSR) markers. In the present study, two hybrid triploid populations derived from doubling the chromosomes of the embryo sac induced by high temperature in Populus tomentosa served as starting materials. Eighty-seven, 62, and 79 SSR markers on chromosomes 01, 04, and 19, respectively, that were heterozygous in the maternal parent and different from the paternal parent were screened to detect and characterize the hDNA in P. tomentosa. The results showed that the hDNA frequency patterns on chromosomes changed slightly when the number of SSR primers increased. The highest hDNA frequency occurred at the adjacent terminal on chromosomes, which was slightly higher than those at the terminals in the two genotypic individuals, and the hDNA frequency gradually decreased as the locus-centromere distance decreased. With the increase in the number of SSR markers employed for detection, the number of recombination events (REs) detected significantly increased. In regions with high methylation or long terminal repeat (LTR) retrotransposon enrichment, the frequency of hDNA was low, and high frequencies were observed in regions with low sequence complexity and high gene density. High-frequency recombination occurring at high gene density regions strongly affected the association between molecular markers and quantitative trait loci (QTLs), which was an important factor contributing to the difficulty encountered by MAS in achieving the expected breeding results.

scholarly journals Global transcript structure resolution of high gene density genomes through multi-platform data integration

2016 ◽  
Vol 44 (18) ◽  
pp. e145-e145 ◽  
Author(s):  
Tina O'Grady ◽  
Xia Wang ◽  
Kerstin Höner zu Bentrup ◽  
Melody Baddoo ◽  
Monica Concha ◽  
...  
Keyword(s):  
Data Integration ◽  
Gene Density ◽  
High Gene ◽  
Transcript Structure ◽  
High Gene Density
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