scholarly journals Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb.

1996 ◽  
Vol 6 (8) ◽  
pp. 688-701 ◽  
Author(s):  
Z F Wang ◽  
T Krasikov ◽  
M R Frey ◽  
J Wang ◽  
A G Matera ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Histone Gene ◽  
Histone Genes ◽  
Chromosome 13

scholarly journals Characterization of the 55-kb mouse histone gene cluster on chromosome 3.

1996 ◽  
Vol 6 (8) ◽  
pp. 702-714 ◽  
Author(s):  
Z F Wang ◽  
R Tisovec ◽  
R W Debry ◽  
M R Frey ◽  
A G Matera ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Histone Gene ◽  
Chromosome 3

Functional Characterization of the Enhancer Blocking Element of the Sea Urchin Early Histone Gene Cluster Reveals Insulator Properties and Three Essential cis-acting Sequences

2000 ◽  
Vol 304 (5) ◽  
pp. 753-763 ◽  
Author(s):  
Raffaella Melfi ◽  
Franco Palla ◽  
Paola Di Simone ◽  
Claudia Alessandro ◽  
Larissa Calı̀ ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Sea Urchin ◽  
Functional Characterization ◽  
Histone Gene ◽  
Cis Acting ◽  
Enhancer Blocking

Functional characterization of a human histone gene cluster duplication

Gene ◽  
2004 ◽  
Vol 342 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Corey D. Braastad ◽  
Hayk Hovhannisyan ◽  
Andre J. van Wijnen ◽  
Janet L. Stein ◽  
Gary S. Stein
Keyword(s):  
Gene Cluster ◽  
Functional Characterization ◽  
Histone Gene

scholarly journals A Role for the Drosophila SU(VAR)3-9 Protein in Chromatin Organization at the Histone Gene Cluster and in Suppression of Position-Effect Variegation

Genetics ◽  
2002 ◽  
Vol 162 (4) ◽  
pp. 1763-1774
Author(s):  
Sarbjit S Ner ◽  
Michael J Harrington ◽  
Thomas A Grigliatti
Keyword(s):  
Gene Cluster ◽  
Chromatin Immunoprecipitation ◽  
Position Effect ◽  
Histone H3 ◽  
Histone Gene ◽  
Chromatin Domain ◽  
Position Effect Variegation ◽  
Histone Genes ◽  
Concomitant Increase ◽  
Effect Variegation

Abstract Mutations in the gene for Su(var)3-9 are dominant suppressors of position-effect variegation (PEV). We show that SU(VAR)3-9 is a chromatin-associated protein and identify the large multicopy histone gene cluster (HIS-C) as one of its target loci. The organization of nucleosomes over the entire HIS-C region is altered in Su(var)3-9 mutants and there is a concomitant increase in expression of the histone genes. SU(VAR)3-9 is a histone H3 methyltransferase and, using chromatin immunoprecipitation, we show that SU(VAR)3-9 is present at the HIS-C locus and that the histone H3 at the HIS-C locus is methylated. We propose that SU(VAR)3-9 is involved in packaging HIS-C into a distinct chromatin domain that has some of the characteristics of β-heterochromatin. We suggest that methylation of histone H3 is important for the chromatin structure at HIS-C. The chromosomal deficiency for the HIS-C is also a suppressor of PEV. In contrast to what might be expected, we show that hemizygosity for the HIS-C locus leads to a substantial increase in the histone transcripts.

scholarly journals Characterization of a cloned histone gene cluster of the newt Notophthalmus viridescens

1981 ◽  
Vol 9 (10) ◽  
pp. 2281-2295 ◽  
Author(s):  
Edwin C. Stephenson ◽  
Harry P. Erba ◽  
Joseph G. Gall
Keyword(s):  
Gene Cluster ◽  
Histone Gene ◽  
Notophthalmus Viridescens
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