scholarly journals Drosophila poised enhancers are generated during tissue patterning with the help of repression

2016 ◽  
Vol 27 (1) ◽  
pp. 64-74 ◽  
Author(s):  
Nina Koenecke ◽  
Jeff Johnston ◽  
Qiye He ◽  
Samuel Meier ◽  
Julia Zeitlinger
Keyword(s):  
Tissue Patterning

scholarly journals Receptor Tyrosine Kinases: Role in Cancer Progression

2006 ◽  
Vol 13 (5) ◽  
pp. 191-193
Author(s):  
V. Sangwan ◽  
M. Park
Keyword(s):  
Cell Proliferation ◽  
Cell Death ◽  
Programmed Cell Death ◽  
Cancer Progression ◽  
Tyrosine Kinases ◽  
Normal Tissue ◽  
Receptor Tyrosine Kinases ◽  
Tight Control ◽  
Tissue Patterning

Tight control of cell proliferation and morphogenesis in conjunction with programmed cell death (apoptosis) is required to ensure normal tissue patterning. [...]

Cell polarity and tissue patterning in plants

Development ◽  
1991 ◽  
Vol 113 (Supplement_1) ◽  
pp. 83-93 ◽  
Author(s):  
Tsvi Sachs
Keyword(s):  
Cell Polarity ◽  
Cell Shape ◽  
Auxin Transport ◽  
Developmental Stages ◽  
Important Determinant ◽  
Genetic System ◽  
Cell Patterning ◽  
Cell Polarization ◽  
Sources And Sinks ◽  
Tissue Patterning

Cell polarization is the specialization of developmental events along one orientation or one direction. Such polarization must be an early, essential stage of tissue patterning. The specification of orientation could not occur only at the level of the genetic system and it must express a coordination of events in many cells. There is a positive feedback relation between cell polarization and the transport of the known hormone auxin: polarity determines oriented auxin transport while transport itself induces both new and continued polarization. Since cell polarization increases gradually, this feedback leads to the canalization of transport – and of the associated cell differentiation – along defined strands of specialized cells. Recent work has shown that the same canalized flow can also be an important determinant of cell shape. In primordial, embryonic regions cell growth is oriented along the flow of auxin from the shoot towards the root. In later developmental stages the cells respond to the same flow by growing in girth, presumably adjusting the capacity of the tissues to the flow of signals. Finally, disrupted flow near wounds results in the development of relatively unorganized callus. Continued callus development appears to require the participation of the cells, as sources and sinks of auxin and other signals. The overall picture to emerge suggests that cell patterning can result from competition between cells acting as preferred channels, sources and sinks for developmental signals.

scholarly journals A functional genomics screen identifies an Importin-α homolog as a regulator of stem cell function and tissue patterning during planarian regeneration

BMC Genomics ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Amy Hubert ◽  
Jordana M. Henderson ◽  
Martis W. Cowles ◽  
Kelly G. Ross ◽  
Matthew Hagen ◽  
...  
Keyword(s):  
Stem Cell ◽  
Functional Genomics ◽  
Cell Function ◽  
Planarian Regeneration ◽  
Tissue Patterning ◽  
Importin Α

scholarly journals Generating a Wnt switch: it’s all about the right dosage

2011 ◽  
Vol 193 (3) ◽  
pp. 431-433 ◽  
Author(s):  
Hans A. Kestler ◽  
Michael Kühl
Keyword(s):  
Wnt Signaling ◽  
Signaling Pathway ◽  
Molecular Mechanisms ◽  
Wnt Signaling Pathway ◽  
Wnt Proteins ◽  
Cell Biol ◽  
Tissue Patterning ◽  
Wnt Ligands ◽  
The Right

Wnt proteins can activate different branches of the Wnt signaling pathway, raising the question of specificity. In this issue, Nalesso et al. (2011. J. Cell Biol. doi:10.1083/jcb.201011051) provide an answer to this conundrum by showing that different concentrations of Wnt ligands can elicit different intracellular responses. These findings not only provide new insights into the molecular mechanisms underlying Wnt signaling, but also indicate how Wnt gradients might contribute to tissue patterning during embryogenesis.

Sign in / Sign up

Export Citation Format

Share Document