scholarly journals Widespread contribution of transposable elements to the innovation of gene regulatory networks

2014 ◽  
Vol 24 (12) ◽  
pp. 1963-1976 ◽  
Author(s):  
Vasavi Sundaram ◽  
Yong Cheng ◽  
Zhihai Ma ◽  
Daofeng Li ◽  
Xiaoyun Xing ◽  
...  
Keyword(s):  
Transposable Elements ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Gene Regulatory

Transposable Elements in the Evolution of Gene Regulatory Networks

2019 ◽  
Vol 55 (1) ◽  
pp. 24-34
Author(s):  
S. A. Pirogov ◽  
O. G. Maksimenko ◽  
P. G. Georgiev
Keyword(s):  
Transposable Elements ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Gene Regulatory

scholarly journals The Role of Gene Conversion between Transposable Elements in Rewiring Regulatory Networks

2019 ◽  
Vol 11 (7) ◽  
pp. 1723-1729
Author(s):  
Jeffrey A Fawcett ◽  
Hideki Innan
Keyword(s):  
Transposable Elements ◽  
Gene Conversion ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Alternative Mechanism ◽  
Beneficial Mutations ◽  
Future Studies ◽  
Cellular Processes ◽  
Gene Regulatory

Abstract Nature has found many ways to utilize transposable elements (TEs) throughout evolution. Many molecular and cellular processes depend on DNA-binding proteins recognizing hundreds or thousands of similar DNA motifs dispersed throughout the genome that are often provided by TEs. It has been suggested that TEs play an important role in the evolution of such systems, in particular, the rewiring of gene regulatory networks. One mechanism that can further enhance the rewiring of regulatory networks is nonallelic gene conversion between copies of TEs. Here, we will first review evidence for nonallelic gene conversion in TEs. Then, we will illustrate the benefits nonallelic gene conversion provides in rewiring regulatory networks. For instance, nonallelic gene conversion between TE copies offers an alternative mechanism to spread beneficial mutations that improve the network, it allows multiple mutations to be combined and transferred together, and it allows natural selection to work efficiently in spreading beneficial mutations and removing disadvantageous mutations. Future studies examining the role of nonallelic gene conversion in the evolution of TEs should help us to better understand how TEs have contributed to evolution.

Sign in / Sign up

Export Citation Format

Share Document