scholarly journals A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription

2002 ◽  
Vol 16 (6) ◽  
pp. 673-675 ◽  
Author(s):  
L. Tora
Keyword(s):  
Rna Polymerase ◽  
Rna Polymerase Ii ◽  
Associated Factors ◽  
Binding Protein ◽  
Tata Box ◽  
Tata Box Binding Protein ◽  
Rna Polymerase Ii Transcription

scholarly journals The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae.

1995 ◽  
Vol 15 (2) ◽  
pp. 983-988 ◽  
Author(s):  
A S Ponticelli ◽  
T S Pardee ◽  
K Struhl
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Rna Polymerase Ii ◽  
Binding Protein ◽  
Tata Box ◽  
Transcriptional Activators ◽  
Yeast Saccharomyces Cerevisiae ◽  
Activation Domains ◽  
Tata Box Binding Protein ◽  
Simplex Virus ◽  
Rna Polymerase Ii Transcription

Eukaryotic transcriptional activators have been classified on the basis of the characteristics of their activation domains. Acidic activation domains, such as those in the yeast GAL4 or GNC4 proteins and the herpes simplex virus activator VP16, stimulate RNA polymerase II transcription when introduced into a variety of eukaryotic cells. This species interchangeability demonstrates that the mechanism by which acidic activation domains function is highly conserved in the eukaryotic kingdom. To determine whether such a conservation of function exists for a different class of activation domain, we have tested whether the glutamine-rich activation domains of the human transcriptional activator Sp1 function in the yeast Saccharomyces cerevisiae. We report here that the glutamine-rich domains of Sp1 do not stimulate transcription in S. cerevisiae, even when accompanied by human TATA-box binding protein (TBP) or human-yeast TATA-box binding protein hybrids. Thus, in contrast to the case for acidic activation domains, the mechanism by which glutamine-rich domains stimulate transcription is not conserved between S. cerevisiae and humans.

Association of TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) with T2DM

Gene ◽  
2019 ◽  
Vol 706 ◽  
pp. 43-51 ◽  
Author(s):  
Rabab Asghar Abdulwahab ◽  
Abdul Ameer A. Allaith ◽  
Zakia Shinwari ◽  
Ayodele Alaiya ◽  
Hayder A. Giha
Keyword(s):  
Rna Polymerase ◽  
Binding Protein ◽  
Rna Polymerase I ◽  
Tata Box ◽  
Subunit C ◽  
Associated Factor ◽  
Tata Box Binding Protein ◽  
Polymerase I
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