scholarly journals The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation

2010 ◽  
Vol 24 (7) ◽  
pp. 683-695 ◽  
Author(s):  
H. K. Liu ◽  
Y. Wang ◽  
T. Belz ◽  
D. Bock ◽  
A. Takacs ◽  
...  
Keyword(s):  
Stem Cell ◽  
Brain Tumor ◽  
Neural Stem Cell ◽  
Nuclear Receptor ◽  
Cell Expansion ◽  
Tumor Initiation ◽  
Stem Cell Expansion

scholarly journals Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

2013 ◽  
Vol 12 (1) ◽  
pp. 88-100 ◽  
Author(s):  
M. Ángeles Marqués-Torrejón ◽  
Eva Porlan ◽  
Ana Banito ◽  
Esther Gómez-Ibarlucea ◽  
Andrés J. Lopez-Contreras ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Expansion ◽  
Kinase Inhibitor ◽  
Cyclin Dependent Kinase ◽  
Adult Neural Stem Cell ◽  
Stem Cell Expansion ◽  
Cyclin Dependent Kinase Inhibitor ◽  
Sox2 Gene

scholarly journals Erratum: Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion

Cell Research ◽  
2015 ◽  
Vol 25 (9) ◽  
pp. 1082-1083 ◽  
Author(s):  
Xin Fu ◽  
Jun Xiao ◽  
Yuning Wei ◽  
Sheng Li ◽  
Yan Liu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Expansion ◽  
Muscle Stem Cell ◽  
Stem Cell Expansion

scholarly journals Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion

Cell Research ◽  
2015 ◽  
Vol 25 (6) ◽  
pp. 655-673 ◽  
Author(s):  
Xin Fu ◽  
Jun Xiao ◽  
Yuning Wei ◽  
Sheng Li ◽  
Yan Liu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Expansion ◽  
Muscle Stem Cell ◽  
Stem Cell Expansion

scholarly journals Extracellular Matrix protein gelatin provides higher expansion, reduces size heterogeneity, and maintains cell stiffness in a long-term culture of mesenchymal stem cells.

2021 ◽  
Author(s):  
Pankaj Mogha ◽  
Shruti Iyer ◽  
Abhijit Majumder
Keyword(s):  
Stem Cells ◽  
Tissue Culture ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Expansion ◽  
Extracellular Matrix Protein ◽  
Stem Cell Expansion ◽  
Ecm Proteins ◽  
Size Heterogeneity

Extracellular matrices (ECM) present in our tissues play a significant role in maintaining tissue homeostasis through various physical and chemical cues such as topology, stiffness, and secretion of biochemicals. They are known to influence the behaviour of resident stem cells. It is also known that ECM type and coating density on cell culture plates strongly influence in vitro cellular behaviour. However, the influence of ECM protein coating on long term mesenchymal stem cell expansion has not been studied yet. To address this gap, we cultured bone-marrow derived hMSCs for multiple passages on the tissue culture plastic plates coated with 25 μg/ml of various ECM proteins. We found that cells on plates coated with ECM proteins had much higher proliferation compared to the regular tissue culture plates. Further, gelatin coated plates helped the cells to grow faster compared to collagen, fibronectin, and laminin coated plates. Additionally, the use of Gelatin showed less size heterogeneity among the cells when expanded from passages P3 to P9. Gelatin also helped in maintaining cellular stiffness which was not observed across other ECM proteins. In summary, in this research, we have shown that gelatin which is the least expensive compared to other ECM proteins provides a better platform for mesenchymal stem cell expansion.

scholarly journals MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex

Cell Reports ◽  
2013 ◽  
Vol 3 (5) ◽  
pp. 1398-1406 ◽  
Author(s):  
Shan Bian ◽  
Janet Hong ◽  
Qingsong Li ◽  
Laura Schebelle ◽  
Andrew Pollock ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Expansion ◽  
Stem Cell Expansion ◽  
Intermediate Progenitors ◽  
Microrna Cluster

scholarly journals Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

2014 ◽  
Vol 289 (8) ◽  
pp. 4626-4633 ◽  
Author(s):  
Amber N. Ziegler ◽  
Shravanthi Chidambaram ◽  
Briony E. Forbes ◽  
Teresa L. Wood ◽  
Steven W. Levison
Keyword(s):  
Stem Cell ◽  
Growth Factor ◽  
Insulin Receptor ◽  
Binding Affinity ◽  
Neural Stem Cell ◽  
Cell Expansion ◽  
Insulin Like Growth Factor ◽  
Stem Cell Expansion ◽  
Factor Ii
Sign in / Sign up

Export Citation Format

Share Document