scholarly journals The Impact of Space and Time on the Functional Output of the Genome

Author(s):  
Marcelo Nollmann ◽  
Isma Bennabi ◽  
Markus Götz ◽  
Thomas Gregor
2017 ◽  
Vol 7 (3) ◽  
pp. 210-223
Author(s):  
Anna Burton

In The Woodlanders (1887), Hardy uses the texture of Hintock woodlands as more than description: it is a terrain of personal association and local history, a text to be negotiated in order to comprehend the narrative trajectory. However, upon closer analysis of these arboreal environs, it is evident that these woodscapes are simultaneously self-contained and multi-layered in space and time. This essay proposes that through this complex topographical construction, Hardy invites the reader to read this text within a physical and notional stratigraphical framework. This framework shares similarities with William Gilpin's picturesque viewpoint and the geological work of Gideon Mantell: two modes of vision that changed the observation of landscape in the eighteenth and nineteenth centuries. This comparative discussion at once reviews the perception of the arboreal prospect in nineteenth-century literary and visual cultures, and also questions the impact of these modes of thought on the woodscapes of The Woodlanders.


2021 ◽  
Vol 43 (4) ◽  
pp. 3-7
Author(s):  
Susan Frohlick ◽  
Adey Mohamed

Abstract This paper traces a collaboration between a White settler anthropologist and Black community liaison and researcher in the design and implementation of HIV awareness strategies. Based on ethnographic research with young people from African newcomer communities who settled in Winnipeg, Canada, their sense that HIV did not exist in Canada was the impetus for our movement of knowledge-to-action. Rather than deliver the facts to them as a passive audience, we created space and time for a series of youth-led conversations that were effective, emotional, corporeal, and socially dynamic. From our respective positionalities, we reflect on the impact of the awareness activity. What at times felt like “a free-for-all” fostered an awareness by the young people, as active agents, of the complexities of HIV as “more than a virus,” especially its racialized underpinnings.


2018 ◽  
Vol 10 (0) ◽  
pp. 1-7
Author(s):  
Huriye Armagan DOGAN

Memento value in heritage is one of the most essential characteristics facilitating the association between the environment and its users, by connecting structures with space and time, moreover, it helps people to identify their surroundings. However, the emergence of the Modern Movement in the architectural sphere disrupted the reflection of memory and symbols which serve to root the society in its language. Furthermore, it generated an approach that stood against the practice of referring to the past and tradition, which led to the built environment becoming homogeneous and deprived of memento value. This paper focuses on the impact of memento value on the perception and evaluation of cultural heritage. Furthermore, it investigates the notions which are perceived to influence the appraisal of cultural heritage by applying them to the Kaunas dialect of the Modern Movement with an empirical approach.


Author(s):  
Devin J. Stewart

This chapter discusses the shari'a, the sacred law of Islam. Law is an essential feature of revealed religion in both the Qur'an and Islamic thought in general, and the term shari'a is used with reference not only to Islam but also to Judaism and Christianity, because all three are conceived as having a divinely given law. According to later jurists, 500 verses of the Qur'an, treat legal subjects, including matters relating to prayer, fasting, alms, pilgrimage, permitted food, marriage, divorce, inheritance, slavery, and trade. This represents roughly one-thirteenth of the sacred text. The chapter covers the law in the books; the source of the law; the two institutions that contributed to making the law central to Islamic societies and creating continuity over space and time: the madhhab, or the legal school and the madrasa, or college of law; legal education and careers; caliphs; judges and muftis; the impact of modernity; and political Islam.


2011 ◽  
Vol 308-310 ◽  
pp. 315-318
Author(s):  
Min Wang

Book design is carried out and elaborated within a space of compact size and limited storage amount. It is not easy to accomplish a novel attractive book design, as innovation is required and connotation of books should be embodied. Especially when faced with the impact from electronic media, we have difficulty designing a book with a strong material sense and rich space and time association if we continue to design a book using single thought for publishment without the sense updating. Conceptual book design, based on the traditional books, is an attempt to seek a new morphological book form which fully incarnates the personality and connotation of a book and seeks to display the possibilities of the book contents. This paper mainly explores the morphosemantic meaning in conceptual book design and expounds features and expressions of morph morphosemantic of conceptual books, in order to contribute to the development of book design.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Misha Mao ◽  
Yifan Cheng ◽  
Jingjing Yang ◽  
Yongxia Chen ◽  
Ling Xu ◽  
...  

AbstractThe role of PLAC8 in tumorigenesis has been gradually elucidated with the development of research. Although there are common molecular mechanisms that enforce cell growth, the impact of PLAC8 is varied and can, in some instances, have opposite effects on tumorigenesis. To systematically understand the role of PLAC8 in tumors, the molecular functions of PLAC8 in cancer will be discussed by focusing on how PLAC8 impacts tumorigenesis when it arises within tumor cells and how these roles can change in different stages of cancer progression with the ultimate goal of suppressing PLAC8-relevant cancer behavior and related pathologies. In addition, we highlight the diversity of PLAC8 in different tumors and its functional output beyond cancer cell growth. The comprehension of PLAC8’s molecular function might provide new target and lead to the development of novel anticancer therapies.


2016 ◽  
Vol 24 (2) ◽  
pp. 179
Author(s):  
Erni - Susanti

The impact of climate change on the outbreak plant pest and disease seems to be likely increased in the future. However, operational information system on the outbreak of pest and disease on horticulture crops which can provide an overview of outbreak and distribution pest both in space and time is still very limited. The objective of the study is to developed prototype information system for providing information regarding area of horticulture pest and disease outbreak both space and time punctually and accurately. SIOPTHor is the early stage study to meet information regarding distribution of pest and disease outbreak. SIOPTHor is developed to performed information system including storage, processing, and analysis of distribution of pest and disease of horticulture data both in space and time on spatial and temporal. Distribution pest and disease attack data on horticulture crops (onions, red peppers and potatoes) for main horticulture crop areas in sub district level of Java were provided by local plant protection stations (BPTPH).. SIOPTHor was developed using waterfall systems development methods. This method consist of five stages, namely requirements analysis, design, implementation/coding, testing/verification and deployment/ maintenance. The software platform used for developing the system includes: 1) operation system Microsoft Windows 7, 2) programming language C#, 3) integrated development environment Microsoft Visual Studio 2008, 4) database management system Microsoft Access 2007, 5) mapper MapWinGIS v.3, 6) and software utilities such as Collapsible Panel, Microsoft Chart for NET, and adobe photoshop portable. The results showed SIOPTHor information system display informations including:1) analysis of pest and disease distribution both in space and time, 2) the Top-k OPT analysis in sub district level, 3) The most severe pest outbreak, and 4) analysis of pest and disease vulnerable index.


Author(s):  
Peter A. Hall

Historical institutionalism embraces models of the polity that acknowledge the impact on political action of the social, economic and political structures in which actors are embedded at particular times and places. In addition to examining how events affect the immediate outcome of interest, it considers how they restructure the institutional or ideological setting so as to condition outcomes at later periods in time. Through a comparison with alternative modes of analysis, this chapter outlines what it means to see politics as a structured process. Taking up the problem of plasticity raised by a second wave of historical institutional analysis, it considers how institutions might be dependent on social coalitions but still factors structuring politics by virtue of how they sustain those coalitions.


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