The lottery of spermatogenesis
AbstractThe causes of male infertility are yet to be fully understood. Here, we propose that male infertility can be partly attributed to the insufficiency of cytoplasmically-inherited proteins in sperms. Using a simple stochastic model of spermatogenesis, we show that in a range of parameters, the proportion of viable sperms can be reduced simply due to stochastic transmission of proteins from spermatogonia to spermatids.
2019 ◽
Vol 17
(2)
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pp. 137-142
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1990 ◽
Vol 116
(2)
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pp. 220-232
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2011 ◽
Vol 411
(3-4)
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pp. 279-289
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1998 ◽
Vol 31
(1)
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pp. L19-L25
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