scholarly journals Frontoparietal connectivity correlates with working memory performance in multiple sclerosis

2019 ◽  
Author(s):  
Alejandra Figueroa-Vargas ◽  
Claudia Cárcamo ◽  
Rodrigo Henríquez-Ch ◽  
Francisco Zamorano ◽  
Ethel Ciampi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Working Memory ◽  
Cognitive Deficit ◽  
Memory Load ◽  
Memory Performance ◽  
Working Memory Capacity ◽  
Theta Activity ◽  
Therapeutic Interventions ◽  
Oscillatory Dynamics ◽  
Phase Amplitude

AbstractWorking Memory (WM) impairment is the most common cognitive deficit of Multiple Sclerosis (MS) patients. However, evidence of its neurobiological mechanisms is scarce. Here we recorded electroencephalographic activity of twenty patients with relapsing-remitting MS and minimal cognitive deficit, and 20 healthy control (HC) subjects while they solved a WM task. In spite of similar performance, the HC group demonstrated both a correlation between temporoparietal theta activity and memory load, and a correlation between medial frontal theta activity and successful memory performances. MS patients did not show theses correlations leading significant differences between groups. Moreover, cortical connectivity analyses using granger causality and phase-amplitude coupling between theta and gamma revealed that HC group, but not MS group, presented a load-modulated progression of the frontal-to-parietal connectivity. This connectivity correlated with working memory capacity in MS groups. This early alterations in the oscillatory dynamics underlaying working memory could be useful for plan therapeutic interventions

EXPRESS: Bored, distracted and forgetful – The impact of mind wandering and boredom on memory encoding

2021 ◽  
pp. 174702182110263
Author(s):  
Philippe Blondé ◽  
Marco Sperduti ◽  
Dominique Makowski ◽  
Pascale Piolino
Keyword(s):  
Working Memory ◽  
Memory Load ◽  
Memory Performance ◽  
Load Condition ◽  
Recognition Task ◽  
Mind Wandering ◽  
Memory Encoding ◽  
Working Memory Load ◽  
Thought Probes ◽  
The Impact

Mind wandering, defined as focusing attention toward task unrelated thoughts, is a common mental state known to impair memory encoding. This phenomenon is closely linked to boredom. Very few studies, however, have tested the potential impact of boredom on memory encoding. Thus, the present study aimed at manipulating mind wandering and boredom during an incidental memory encoding task, to test their differential impact on memory encoding. Thirty-two participants performed a variant of the n-back task in which they had to indicate if the current on-screen object was the same as the previous one (1-back; low working memory load) or the one presented three trials before (3-back; high working memory load). Moreover, thought probes assessing either mind wandering or boredom were randomly presented. Afterward, a surprise recognition task was delivered. Results showed that mind wandering and boredom were highly correlated, and both decreased in the high working memory load condition, while memory performance increased. Although both boredom and mind wandering predicted memory performance taken separately, we found that mind wandering was the only reliable predictor of memory performance when controlling for boredom and working memory load. Model comparisons also revealed that a model with boredom only was outperformed by a model with mind wandering only and a model with both mind wandering and boredom, suggesting that the predictive contribution of boredom in the complete model is minimal. The present results confirm the high correlation between mind wandering and boredom and suggest that the hindering effect of boredom on memory is subordinate to the effect of mind wandering.

Greater Visual Working Memory Capacity for Visually Matched Stimuli When They Are Perceived as Meaningful

2021 ◽  
Vol 33 (5) ◽  
pp. 902-918 ◽  
Author(s):  
Isabel E. Asp ◽  
Viola S. Störmer ◽  
Timothy F. Brady
Keyword(s):  
Working Memory ◽  
Visual Working Memory ◽  
Visual Information ◽  
Memory Performance ◽  
Working Memory Capacity ◽  
Visual Complexity ◽  
Memory Capacity ◽  
Subjective Perception ◽  
Neural Delay ◽  
Meaningful Stimuli

Abstract Almost all models of visual working memory—the cognitive system that holds visual information in an active state—assume it has a fixed capacity: Some models propose a limit of three to four objects, where others propose there is a fixed pool of resources for each basic visual feature. Recent findings, however, suggest that memory performance is improved for real-world objects. What supports these increases in capacity? Here, we test whether the meaningfulness of a stimulus alone influences working memory capacity while controlling for visual complexity and directly assessing the active component of working memory using EEG. Participants remembered ambiguous stimuli that could either be perceived as a face or as meaningless shapes. Participants had higher performance and increased neural delay activity when the memory display consisted of more meaningful stimuli. Critically, by asking participants whether they perceived the stimuli as a face or not, we also show that these increases in visual working memory capacity and recruitment of additional neural resources are because of the subjective perception of the stimulus and thus cannot be driven by physical properties of the stimulus. Broadly, this suggests that the capacity for active storage in visual working memory is not fixed but that more meaningful stimuli recruit additional working memory resources, allowing them to be better remembered.

scholarly journals Contralateral Delay Activity Tracks Fluctuations in Working Memory Performance

2018 ◽  
Vol 30 (9) ◽  
pp. 1229-1240 ◽  
Author(s):  
Kirsten C. S. Adam ◽  
Matthew K. Robison ◽  
Edward K. Vogel
Keyword(s):  
Working Memory ◽  
Individual Differences ◽  
Memory Load ◽  
Memory Performance ◽  
Memory Task ◽  
Memory Storage ◽  
Alpha Power ◽  
Working Memory Load ◽  
Contralateral Delay Activity ◽  
Trial Performance

Neural measures of working memory storage, such as the contralateral delay activity (CDA), are powerful tools in working memory research. CDA amplitude is sensitive to working memory load, reaches an asymptote at known behavioral limits, and predicts individual differences in capacity. An open question, however, is whether neural measures of load also track trial-by-trial fluctuations in performance. Here, we used a whole-report working memory task to test the relationship between CDA amplitude and working memory performance. If working memory failures are due to decision-based errors and retrieval failures, CDA amplitude would not differentiate good and poor performance trials when load is held constant. If failures arise during storage, then CDA amplitude should track both working memory load and trial-by-trial performance. As expected, CDA amplitude tracked load (Experiment 1), reaching an asymptote at three items. In Experiment 2, we tracked fluctuations in trial-by-trial performance. CDA amplitude was larger (more negative) for high-performance trials compared with low-performance trials, suggesting that fluctuations in performance were related to the successful storage of items. During working memory failures, participants oriented their attention to the correct side of the screen (lateralized P1) and maintained covert attention to the correct side during the delay period (lateralized alpha power suppression). Despite the preservation of attentional orienting, we found impairments consistent with an executive attention theory of individual differences in working memory capacity; fluctuations in executive control (indexed by pretrial frontal theta power) may be to blame for storage failures.

Visuospatial Working Memory Capacity in the Brain After Working Memory Training in College Students With ADHD: A Randomized Controlled Trial

2019 ◽  
pp. 108705471987948 ◽  
Author(s):  
Steven Woltering ◽  
Chao Gu ◽  
Zhong-Xu Liu ◽  
Rosemary Tannock
Keyword(s):  
College Students ◽  
Working Memory ◽  
Controlled Trial ◽  
Memory Performance ◽  
Working Memory Capacity ◽  
Memory Training ◽  
Treatment Groups ◽  
Before And After ◽  
Students With Adhd ◽  
The Brain

Objective: ADHD has been associated with persistent problems of working memory. This study investigated the efficacy of an intensive and adaptive computerized working memory treatment (CWMT) at behavioral and neural levels. Method: College students ( n = 89; 40 females) with ADHD were randomized into a standard-length CWMT (45 min/session, 25 sessions, n = 29), shortened-length CWMT (15 min/session, 25 sessions, n = 32), and a waitlist group ( n = 28). Both CWMT groups received treatment for 5 days a week for 5 weeks. Lab sessions before and after CWMT assessed electroencephalography (EEG) indicators of working memory, behavioral indicators of working memory performance, and ADHD symptomatology. Results: No evidence was found for neural or any other behavioral transfer effects of improvement for the CWMT treatment groups over the active control or waitlist group. Conclusion: Our study does not provide evidence for the benefits of CWMT at neural or behavioral levels.

Cerebral Activation Patterns During Working Memory Performance in Multiple Sclerosis Using fMRI

2005 ◽  
Vol 27 (1) ◽  
pp. 33-54 ◽  
Author(s):  
Nancy D. Chiaravalloti ◽  
Frank G. Hillary ◽  
Joseph H. Ricker ◽  
Christopher Christodoulou ◽  
Andrew J. Kalnin ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Working Memory ◽  
Memory Performance ◽  
Cerebral Activation ◽  
Activation Patterns

Brain correlates of action word memory

2018 ◽  
Author(s):  
Zubaida Shebani ◽  
Francesca Carota ◽  
Olaf Hauk ◽  
James B. Rowe ◽  
Lawrence W. Barsalou ◽  
...  
Keyword(s):  
Working Memory ◽  
Motor Cortex ◽  
Verbal Memory ◽  
Memory Load ◽  
Memory Performance ◽  
Verbal Working Memory ◽  
The Body ◽  
Action Perception ◽  
Brain Correlates ◽  
Posterior Parietal

AbstractWhen understanding language semantically related to actions, the motor cortex is active and may be sensitive to semantic information, for example about the body-part-relationship of displayed action-related words. Conversely, movements of the hands or feet can impair memory performance for arm- and leg-related action words respectively, suggesting that the role of motor systems extends to verbal working memory. Here, we studied brain correlates of verbal memory load for action-related words using event-related fMRI during the encoding and memory maintenance of word lists. Seventeen participants saw either four identical or four different words from the same category, semantically related to actions typically performed either with the arms or with the legs. After a variable delay of 4-14 seconds, they performed a nonmatching-to-sample task. Hemodynamic activity related to the information load of words at presentation was most prominent in left temporo-occipital and bilateral posterior-parietal areas. In contrast, larger demand on verbal memory maintenance produced greater activation in left premotor and supplementary motor cortex, along with posterior-parietal areas, indicating that verbal memory circuits for action-related words include the cortical action system. Somatotopic memory load effects of arm- and leg-related words were not present at the typical precentral loci where earlier studies had found such word-category differences in reading tasks, although traces of somatotopic semantic mappings were observed at more anterior cortical regions. These results support a neurocomputational model of distributed action-perception circuits (APCs), according to which language understanding is manifest as full ignition of APCs, whereas working memory is realized as reverberant activity gradually receding to multimodal prefrontal and lateral temporal areas.

scholarly journals Frontoparietal connectivity correlates with working memory performance in multiple sclerosis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Alejandra Figueroa-Vargas ◽  
Claudia Cárcamo ◽  
Rodrigo Henríquez-Ch ◽  
Francisco Zamorano ◽  
Ethel Ciampi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Working Memory ◽  
Memory Performance

scholarly journals Learning to suppress a distractor is not affected by working memory load

2019 ◽  
Vol 27 (1) ◽  
pp. 96-104 ◽  
Author(s):  
Ya Gao ◽  
Jan Theeuwes
Keyword(s):  
Working Memory ◽  
High Probability ◽  
Spatial Working Memory ◽  
Memory Load ◽  
Working Memory Capacity ◽  
Memory Task ◽  
Automatic Process ◽  
Long Term Memory ◽  
Working Memory Load ◽  
Statistical Regularities

AbstractWhere and what we attend to is not only determined by our current goals but also by what we have encountered in the past. Recent studies have shown that people learn to extract statistical regularities in the environment resulting in attentional suppression of high-probability distractor locations, effectively reducing capture by a distractor. Here, we asked whether this statistical learning is dependent on working memory resources. The additional singleton task in which one location was more likely to contain a distractor was combined with a concurrent visual working memory task (Experiment 1) and a spatial working memory task (Experiment 2). The result showed that learning to suppress this high-probability location was not at all affected by working memory load. We conclude that learning to suppress a location is an implicit and automatic process that does not rely on visual or spatial working memory capacity, nor on executive control resources. We speculate that extracting regularities from the environment likely relies on long-term memory processes.

Sign in / Sign up

Export Citation Format

Share Document